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MAC Research

There are two types of research studies at the MAC:

What are Observational Studies?
In observational studies, researchers study specific areas or topics related to a particular disease or symptom. No medications or treatment are given. Instead, participants are interviewed, observed, or complete questionnaires. The information helps doctors understand diseases better and make more accurate diagnoses.

The MAC conducts several observational studies on how certain causes of dementia affect the brain. Depending on the study, individuals may enroll in several studies simultaneously. In some studies at the MAC, data from healthy volunteers is compared to data from patients.

What are Clinical Trials?
Clinical trials study the safety and effectiveness of new treatments such as drugs or medical devices. Research staff must follow protocols and rules set by the federal government. The rules ensure that clinical trial participants are treated as safely as possible.

The MAC conducts several clinical trials studying new drugs for Alzheimer disease, frontotemporal dementia, Huntington disease, and Creutzfeldt-Jakob disease.

Observational Studies

Chinese Population: Understanding Dementia in Chinese Individuals

Alzheimer's Disease (AD)

Corticobasal Degeneration (CBD)

Frontotemporal Dementia (FTD), Primary Progressive Aphasia (PPA), Semantic Dementia (SD)

Frontotemporal Dementia (FTD) with Amytrophic Lateral Sclerosis (ALS)

Huntington's Disease (HD)

Mild Cognitive Impairment (MCI)

Progressive Supranuclear Palsy (PSP)

Rapidly Progressive Dementias

Transmissible Spongiform Encephalopathies

Vascular Dementia (VaD)

Healthy Adults

Treatment Studies (or “Clinical Trials”)

Alzheimer's Disease (AD)


Creutzfeldt-Jakob Disease (CJD)


Frontotemporal Dementia (FTD) or Semantic Dementia (SD)


Mild Cognitive Impairment (MCI)

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