Tag Archives: AD

Alzheimer’s Disease Spreads Through Linked Nerve Cells, Brain Imaging Studies Suggest

UCSF Finding Raises Hopes to Use MRI to Predict Disease Progression

Alzheimer’s disease and other forms of dementia may spread within nerve networks in the brain by moving directly between connected neurons, instead of in other ways proposed by scientists, such as by propagating in all directions, according to researchers who report the finding in the March 22 edition of the journal Neuron. Read more

Defining a Disease

The new diagnostic criteria for bvFTD and why they matter

For years, the medical and scientific community considered frontotemporal dementia (FTD) a rare disease that could not be distinguished from Alzheimer’s disease (AD) until after a patient’s death. As our technology and understanding have improved, so has our ability to diagnose disease. A correct diagnosis helps not only the patient and family put a name to their experience, but also helps physicians direct treatment and determine research opportunities. Doctors use specific, validated criteria to confirm a suspected diagnosis. Read more

Amyloid Imaging Accurately Differentiates AD and FTD

A new type of PET scan can accurately distinguish between Alzheimer’s disease and frontotemporal dementia

Plaques made of amyloid protein are a defining feature of Alzheimer’s disease (AD) but are not typically seen in frontotemporal dementia (FTD). Unfortunately these plaques have not been able to be definitively identified until after the death of a patient, when tissue collected during an autopsy is analyzed with a microscope. Scientists have been searching for a disease marker that can be seen in living people for both accurate diagnosis and tracking the effectiveness of potential therapies. New research shows a marker developed to detect plaque in the brain may help doctors make a more accurate diagnosis between Alzheimer’s and FTD. Read more