Collaboration between the UCSF Memory and Aging Center and Mayo Clinic identifies a new single gene cause of Lou Gehrig’s disease and frontotemporal dementia
Rumors started buzzing about five years ago when six different groups of scientists began narrowing in on a region of chromosome 9 to explain what they were seeing in the clinic. Frontotemporal dementia (FTD), a behavioral and cognitive neurodegenerative disease, and amyotrophic lateral sclerosis (ALS or Lou Gehrig’s disease), a neuromuscular degenerative disease, often run in the same family and may even appear in the same person. Narrowing down the right chromosome was a start, but chromosome 9 has 1534 genes on it. How do you find the right one? Read more