One year ago, a consortium of just over 20 international clinician-scientists came together to understand, and ultimately treat and cure, tau-related disorders (tauopathies) including progressive supranuclear palsy (PSP), frontotemporal dementia with parkinsonism (FTD-P) and corticobasal degeneration (CBD). Read more
Tag Archives: protein
The pathological hallmark of tauopathies still holds mysteries
Normal tau protein is found in the axons of healthy neurons and is critical to the healthy functioning of a normal nervous system. It stabilizes the microtubules that form the supportive framework of the neuron and provide the tracks for oxygen proteins and glucose to move within the neuron. Changes in the tau protein can lead to instability in the microtubules, which makes it difficult for neurons to survive.