Tag Archives: PSP

A new clinical trial for people with progressive supranuclear palsy may open the door for other treatments

Progressive supranuclear palsy (PSP) is a degenerative brain disease leading to difficulties with walking and balance, problems with eye movements, changes in behavior and executive control, difficulty with speech and swallowing, and dementia. PSP, corticobasal degeneration (CBD) and some of the frontotemporal dementias (FTD) are tauopathies—diseases associated with the abnormal accumulation of the protein tau. It is likely that whether one presents with PSP, CBD or FTD depends in part on the location in the brain of these microscopic changes, although individual differences may play an important role as well. Read more

Neurologists at UCSF have studied a group of people who suffer from two neurological disorders at the same time: Alzheimer’s disease and a movement disorder called progressive supranuclear palsy.

Their study assessed the cognitive impairments in this group and characterized their behavioral abnormalities. The clinical features of the two diseases together, the researchers say, are more than a simple combination of the two.
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One year ago, a consortium of just over 20 international clinician-scientists came together to understand, and ultimately treat and cure, tau-related disorders (tauopathies) including progressive supranuclear palsy (PSP), frontotemporal dementia with parkinsonism (FTD-P) and corticobasal degeneration (CBD). Read more