Tag Archives: tau

The Lost Wife

She stares at me, owl-eyed, empty. There is no embarrassment when time ticks on. She stares. A sound breaks her gaze and her eyes lock on to a new target. She is nowhere to be found. The old her, that is. The woman who showed such immense joy and love as a mother is gone. Her husband moves her around the streets of their city like he is pulling a 100-pound weight on wheels in his hand. She goes with the flow. He and the children have built a life around this new woman – this wife and mother who is lost to a genetic disease that has stolen everything human about her. She is only 38 years old. She no longer speaks. She stares. She is led to the bathroom, to the shower, to the table where they put a fork or spoon in her hand for her to eat. Read more

Q&A from 2015 Research Education Event

On Saturday, March 21, 2015, the UCSF Memory and Aging Center hosted our annual Research Education Event. After a series of presentations and a lively Q&A, there were still some unanswered questions. We tried to address them here for you, but please feel free to post more questions in the comments, if we didn’t quite answer it for you.

Videos of the talks will be posted on our YouTube channel shortly.

We hope you find these answers helpful.

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Finding Treatments, One at a Time

A new clinical trial for people with progressive supranuclear palsy may open the door for other treatments

Progressive supranuclear palsy (PSP) is a degenerative brain disease leading to difficulties with walking and balance, problems with eye movements, changes in behavior and executive control, difficulty with speech and swallowing, and dementia. PSP, corticobasal degeneration (CBD) and some of the frontotemporal dementias (FTD) are tauopathies—diseases associated with the abnormal accumulation of the protein tau. It is likely that whether one presents with PSP, CBD or FTD depends in part on the location in the brain of these microscopic changes, although individual differences may play an important role as well. Read more