About the article
Most Recent
- Prion disease: Thorough w......Sporadic Creutzfeldt–Jakob disease (sCJD), the prototypical rapidly progressive dementia (RPD), is......read the complete article
- Diffusion-weighted MRI hy......Background: Diffusion-weighted imaging (DWI) and fluid-attenuated inversion recovery (FLAIR) ......read the complete article
- PrionsThe discovery of infectious proteins, denoted prions, was unexpected. After much debate over the che......read the complete article
- Pathologic evidence that ......Human prion diseases can be caused by mutations in the prion protein gene PRNP. Prion disease with m......read the complete article
- Variably protease-sensiti......Objective: The objective of the study is to report 2 new genotypic forms of protease-sensitiv......read the complete article
News & Articles
Scientists sniff out prion secret
The brain protein which has a hand, when defective, in the lethal disease CJD may also be involved in aiding our sense of smell.
Mice bred to lack the prion protein could not find buried food or choose between smells.
Columbia University scientists said some symptoms of prion disease might be due to the loss of the protein's original role.
The study was published in the journal Nature Neuroscience.
The prion protein has historically received something of a bad press, being blamed in its misshapen form for degenerative brain diseases in humans and other animals.
However, many scientists have been trying to uncover what it actually does when it is behaving correctly.
Dr Stuart Firestein's team believe that one of these roles is to help us smell.