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Human growth hormone
Hormones derived from the pituitary glands in the brains of cadaver donors were administered between 1963 and 1985 to infertile women and children with pituitary insufficiency. Most countries abandoned human-derived pituitary hormones in 1985 once the risk of CJD was recognized and a synthetic version was developed. New cases of iatrogenic CJD from human-derived growth hormone have sharply declined in recent years.
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