Sporadic

Sporadic Creutzfeldt-Jakob disease (sCJD)

The cause of "classic" or "sporadic" CJD is unknown, which means it occurs in people without any known risk factors or gene mutations. Typical symptoms include imbalance and incoordination, memory loss and impaired thinking, and psychiatric symptoms such as anxiety or depression. Once the symptoms do appear, CJD progresses very quickly and is usually fatal within a few months of symptom onset. sCJD typically affects people in their 60s and is rarely seen in people younger than 40 years old. Sporadic CJD is the most common form.

Sporadic Fatal Insomnia (sFI)

Like sCJD, sFI is caused by a misfolded protein, but also like sCJD, what causes that protein to misfold is unknown. Symptoms include difficulty falling asleep (insomnia), difficulty walking, weight loss and excessive tears in the eye. The symptoms rapidly progress to loss of consciousness and death.

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