Creation of Stem Cells from Patients with FTD

Purpose of the Study

The purpose of this study is to study the disease-causing mechanisms of frontotemporal dementia (FTD) and create models to study neurological diseases for which there are not adequate human or animal models.

Eligibility

Inclusion Criteria: Participants must have a diagnosis of frontotemporal dementia (FTD) and a known or potential genetic alteration causing the disease. Patients with other closely related neurological disorders, healthy unaffected relatives and other healthy controls may also be included.

Exclusion Criteria: Subjects carrying infectious diseases (e.g., HIV, HCV, HBV, syphilis) will be excluded for laboratory safety reasons. Subjects with known wound-healing problems will be excluded.

What to Expect

Testing: A skin biopsy and virus testing for HIV, hepatitis B and C, and syphilis

The Frequency of Visits: One visit

Materials Needed Before Evaluation: None

Costs: No costs will be charged for any of the study procedures. Participants are responsible for their travel and hotel, should they choose to stay in one.

Contact information

If you are interested in participating in this study or have any questions, please contact the study coordinator, Anna Karydas, at Anna.Karydas@ucsf.edu or 415.476.3377.