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Pathology, diagnosis and discussion

Progressive supranuclear palsy (PSP) was seen at pathology.

This patient began with PNFA but soon afterward exhibited findings suggestive of PSP including falls, the inability to look up or down and axial rigidity. The association of PSP and corticobasal degeneration (CBD) with PNFA is now well recognized, and the majority of patients with PNFA show PSP or CBD on postmortem examination.