Eligibility

Inclusion criteria: Subjects must be enrolled in the Frontotemporal Dementia: Genes, Images and Emotions [1], Larry L. Hillblom study of Healthy Aging [2], UCSF Alzheimer’s Disease Research Center [3], or Aging Brain - Vasculature, Ischemia and Behavior [4]. Subjects must meet criteria for one of the neurodegenerative diseases studied (behavioral variant frontotemporal dementia (bvFTD) [5], Alzheimer's disease (AD) [6], semantic dementia (SD) [7], progressive nonfluent aphasia (PNFA) [8], corticobasal degeneration (CBD) [9], dementia with Lewy bodies (DLB) [10], progressive supranuclear palsy (PSP) [11] and cerebrovascular disease (VaD) [12]), unless participating as a healthy volunteer [13]. Subjects must also have a Mini Mental State Exam (MMSE) score above 15 and be able to understand testing procedures.
Exclusion criteria: Subjects who do not have an informant who has known the subject for more than 5 years and is willing to participate in the questionnaire portion of the evaluation, have a Clinical Dementia Rating Scale of more than 2.0, are unable to cooperate with testing procedures, or have neurologic findings that suggest a prominent non-neurodegenerative cause for cognitive/functional changes will be excluded.

Links:
[1] http://memory.ucsf.edu/ftd/research/clinical/ppg/multiple
[2] http://memory.ucsf.edu/ftd/research/clinical/aging/multiple
[3] http://memory.ucsf.edu/ftd/research/clinical/heterogeneity/multiple
[4] http://memory.ucsf.edu/Research/Studies/OS_Miller_AgingBrain.htm
[5] http://memory.ucsf.edu/ftd/overview/forms/multiple
[6] http://memory.ucsf.edu/Education/Disease/ad.html
[7] http://memory.ucsf.edu/ftd/overview/forms/multiple/multiple/sd
[8] http://memory.ucsf.edu/ftd/overview/forms/multiple/pnfa
[9] http://memory.ucsf.edu/Education/Disease/cbd.html
[10] http://memory.ucsf.edu/Education/Disease/dlb.html
[11] http://memory.ucsf.edu/Education/Disease/psp.html
[12] http://memory.ucsf.edu/Education/Disease/vad.html
[13] http://memory.ucsf.edu/Education/Topics/normalaging.html