What is involved?

• Testing: Neurological and physical examinations; interview with study partner; MRIs; cognitive testing; detailed family history; blood specimen collection for genetic testing and cell line generation; behavioral, emotional and personality testing; questionnaires for participant and study partner; pre-consent to obtain a brain autopsy. Participants will be asked to participate in additional studies affiliated with this project.
• Frequency of visits: Depending on the individual, there will be 4 to 6 visits over a three month period of time, each year for up to five years. Participants may choose to participate as an inpatient, staying in Moffitt Hospital in the Clinical & Translational Science Institute (CTSI) Clinical Research Center, and complete the visits in one week or as an outpatient and spread the visits out over three months.
• Materials needed prior to evaluation: MRI scan and medical records
• Costs: No costs will be charged for any of the study procedures. For those who choose to stay in the hospital, there are no costs associated with the stay. Parking will be validated for Millberry Parking Garage for study visit. Participants are responsible for their travel and hotel, should they choose to stay in one.