Ethan Geier, PhD

Postdoctoral Fellow
Neurology
+1 415 476-8101
Publications: 

Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study.

PLoS medicine

Steele NZ, Carr JS, Bonham LW, Geier EG, Damotte V, Miller ZA, Desikan RS, Boehme KL, Mukherjee S, Crane PK, Kauwe JS, Kramer JH, Miller BL, Coppola G, Hollenbach JA, Huang Y, Yokoyama JS

Expression and splicing of ABC and SLC transporters in the human blood-brain barrier measured with RNAseq.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Suhy AM, Webb A, Papp AC, Geier EG, Sadee W

Rare TREM2 variants associated with Alzheimer's disease display reduced cell surface expression.

Acta neuropathologica communications

Sirkis DW, Bonham LW, Aparicio RE, Geier EG, Ramos EM, Wang Q, Karydas A, Miller ZA, Miller BL, Coppola G, Yokoyama JS

Age-dependent effects of APOE e4 in preclinical Alzheimer's disease.

Annals of clinical and translational neurology

Bonham LW, Geier EG, Fan CC, Leong JK, Besser L, Kukull WA, Kornak J, Andreassen OA, Schellenberg GD, Rosen HJ, Dillon WP, Hess CP, Miller BL, Dale AM, Desikan RS, Yokoyama JS

Targeted disruption of organic cation transporter 3 attenuates the pharmacologic response to metformin.

Molecular pharmacology

Chen EC, Liang X, Yee SW, Geier EG, Stocker SL, Chen L, Giacomini KM

Phase I Study of Vorinostat as a Radiation Sensitizer with 131I-Metaiodobenzylguanidine (131I-MIBG) for Patients with Relapsed or Refractory Neuroblastoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

DuBois SG, Groshen S, Park JR, Haas-Kogan DA, Yang X, Geier E, Chen E, Giacomini K, Weiss B, Cohn SL, Granger MM, Yanik GA, Hawkins R, Courtier J, Jackson H, Goodarzian F, Shimada H, Czarnecki S, Tsao-Wei D, Villablanca JG, Marachelian A, Matthay KK

Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statins.

Drug metabolism and disposition: the biological fate of chemicals

Salphati L, Chu X, Chen L, Prasad B, Dallas S, Evers R, Mamaril-Fishman D, Geier EG, Kehler J, Kunta J, Mezler M, Laplanche L, Pang J, Rode A, Soars MG, Unadkat JD, van Waterschoot RA, Yabut J, Schinkel AH, Scheer N

Conservation of apolipoprotein A-I's central domain structural elements upon lipid association on different high-density lipoprotein subclasses.

Biochemistry

Oda MN, Budamagunta MS, Geier EG, Chandradas SH, Shao B, Heinecke JW, Voss JC, Cavigiolio G

Profiling solute carrier transporters in the human blood-brain barrier.

Clinical pharmacology and therapeutics

Geier EG, Chen EC, Webb A, Papp AC, Yee SW, Sadee W, Giacomini KM

Structure-based ligand discovery for the Large-neutral Amino Acid Transporter 1, LAT-1.

Proceedings of the National Academy of Sciences of the United States of America

Geier EG, Schlessinger A, Fan H, Gable JE, Irwin JJ, Sali A, Giacomini KM

Gene expression profiling of transporters in the solute carrier and ATP-binding cassette superfamilies in human eye substructures.

Molecular pharmaceutics

Dahlin A, Geier E, Stocker SL, Cropp CD, Grigorenko E, Bloomer M, Siegenthaler J, Xu L, Basile AS, Tang-Liu DD, Giacomini KM

Evaluation of Norepinephrine Transporter Expression and Metaiodobenzylguanidine Avidity in Neuroblastoma: A Report from the Children's Oncology Group.

International journal of molecular imaging

Dubois SG, Geier E, Batra V, Yee SW, Neuhaus J, Segal M, Martinez D, Pawel B, Yanik G, Naranjo A, London WB, Kreissman S, Baker D, Attiyeh E, Hogarty MD, Maris JM, Giacomini K, Matthay KK

Structure-based discovery of prescription drugs that interact with the norepinephrine transporter, NET.

Proceedings of the National Academy of Sciences of the United States of America

Schlessinger A, Geier E, Fan H, Irwin JJ, Shoichet BK, Giacomini KM, Sali A

Vorinostat increases expression of functional norepinephrine transporter in neuroblastoma in vitro and in vivo model systems.

Clinical cancer research : an official journal of the American Association for Cancer Research

More SS, Itsara M, Yang X, Geier EG, Tadano MK, Seo Y, Vanbrocklin HF, Weiss WA, Mueller S, Haas-Kogan DA, Dubois SG, Matthay KK, Giacomini KM

Role of the copper transporter, CTR1, in platinum-induced ototoxicity.

The Journal of neuroscience : the official journal of the Society for Neuroscience

More SS, Akil O, Ianculescu AG, Geier EG, Lustig LR, Giacomini KM

The interplay between size, morphology, stability, and functionality of high-density lipoprotein subclasses.

Biochemistry

Cavigiolio G, Shao B, Geier EG, Ren G, Heinecke JW, Oda MN