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UCSF Over 80 Clinic

The staff of the UCSF Over 80 Clinic seek to address the complex dementia care issues commonly seen when caring for the oldest old. This care often requires an in-depth understanding of co-existing non-dementia medical illnesses, medication interactions, and the integrated living environment encountered in care of elders.

The staff of the UCSF Over 80 Clinic seek to address the complex dementia care issues commonly seen when caring for the oldest old. This care often requires an in-depth understanding of co-existing non-dementia medical illnesses, medication interactions, and the integrated living environment encountered in care of elders. In contrast to the clinical priorities for younger patients with cognitive decline, diagnosis is often only a small factor in maximizing outcomes.

Christine Walsh, PhD

Postdoctoral Fellow

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Christine M. Walsh, PhD, received her BA degree in physiology from Trinity College Dublin, University of Dublin in Ireland. Dr. Walsh did her doctoral work at the University of Michigan studying the effects of REM sleep modulation on learning and memory. She also studied the neural correlates of cognitive aging. In 2011 Dr. Walsh joined the UCSF Memory and Aging Center where she has been studying sleep in both healthy older adults and in individuals with neurodegenerative diseases. Dr. Walsh is particularly interested in the contribution of sleep disturbance to cognitive decline.

Iryna V. Lobach, PhD

Assistant Professor

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Iryna earned her PhD degree in statistics under the direction of Raymond J. Carroll at the Texas A&M University where she wrote a dissertation on the interaction of haplotypes and diet. In 2006–2008 she attended Yale University for postdoctoral training in statistical genetics. After spending four years as an Assistant Professor of Biostatistics at the New York University, Iryna joined the UCSF Memory and Aging Center (MAC) to support the biostatistics component of research conducted by MAC investigators.

In addition to collaborative research with MAС principal investigators, Iryna enjoys research in applied statistics. She works on advancing existing and developing novel methodologies for analysis of gene-environment interactions in situations when the environmental variable is difficult to measure at the individual level and when the genetic influence is of complex multivariate nature.

Make a Referral

Thank you for considering a referral to the UCSF Memory and Aging Center. We appreciate the opportunity to provide consultation services to you and your patients. The clinical services at the Memory and Aging Center are focused on providing a diagnostic evaluation and treatment recommendations for neurodegenerative diseases. This includes diagnoses such as Alzheimer’s disease, vascular dementia and dementia with Lewy bodies as well as less common disorders such as frontotemporal dementia, Huntington’s disease and Creutzfeldt-Jakob disease. We also have a specialty clinic for patients with cognitive complaints that may be associated with movement disorders or genetic conditions. If you have questions about the process or would like to speak with someone about a referral, please call 415-353-2057.

Thank you for considering a referral to the UCSF Memory and Aging Center. We appreciate the opportunity to provide consultation services to you and your patients. The clinical services at the Memory and Aging Center are focused on providing a diagnostic evaluation and treatment recommendations for neurodegenerative diseases.

Kelly Hitchner

Administrative Manager

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Kelly completed her Bachelor of Science degree in molecular biology at the University of California, San Diego in 2011. Kelly has four years of research experience at the Dorris Neuroscience Center at The Scripps Research Institute and the Institute of Regenerative Medicine at UCSF. She joined the UCSF Memory and Aging Center in 2013 and works with Dr. William Seeley to manage the Neurodegenerative Disease Brain Bank.

Contact Us

For more information about the Neurodegenerative Disease Brain Bank (NDBB) and its tissue sharing procedure, please contact the administrative manager. For questions about the Autopsy Program, please contact the autopsy coordinator.

For more information about the Neurodegenerative Disease Brain Bank (NDBB) and its tissue sharing procedure, please contact the administrative manager at 415-502-7459.

For questions about the Autopsy Program, please contact the autopsy coordinator at 415-476-1681 or autopsy@memory.ucsf.edu.

Neurodegenerative Disease Brain Bank (NDBB) Director
William Seeley, MD
Associate Professor of Neurology
UCSF Memory and Aging Center
415-476-2793
wseeley@memory.ucsf.edu

What We're Learning

Many new discoveries have been published in peer-reviewed papers using data from the Neurodegenerative Disease Brain Bank (NDBB).

Recent publications using data from the Neurodegenerative Disease Brain Bank (NDBB) include:

  1. Boxer AL, Garbutt S, Seeley WW, Jafari A, Heuer HW, Mirsky J, Hellmuth J, Trojanowski JQ, Huang E, Dearmond S, Neuhaus J, Miller BL. Saccade abnormalities in autopsy-confirmed frontotemporal lobar degeneration and Alzheimer disease. Arch Neurol. 2012;69:509-17.

Request Tissue

Tissue is shared with investigators whose research is of superb scientific quality and occurs under the provision of a Material Transfer Agreement (MTA).

Tissue is shared with investigators whose research is of superb scientific quality and occurs under the provision of a Material Transfer Agreement (MTA). The MTA restricts the use of tissue to one study, prohibits the transfer of tissue to anyone outside the recipient organization without prior written approval of the NDBB, and requires the recipient organization to cite the contribution of the NDBB in any publications resulting from the use of the tissue. MTA request applications are reviewed by the UCSF Memory and Aging Center Resource Request Committee.

Brain Donation

Brain donation provides individuals the opportunity to help others affected by dementia by advancing our scientific understanding of neurodegenerative diseases and healthy aging. We honor the gift of donation and treat donors, their bereaved families, and all tissue with care and respect.

Why donate?

Brain donation provides individuals the opportunity to help others affected by dementia by advancing our scientific understanding of neurodegenerative diseases and healthy aging. We honor the gift of donation and treat donors, their bereaved families, and all tissue with care and respect.

Examining the brain after death is currently the only way to obtain a definitive diagnosis of the underlying causes of dementia. A diagnosis of absolute certainty cannot be made by clinical evaluation alone.

About Us

The Neurodegenerative Disease Brain Bank (NDBB) was established in 2008 and serves as a repository for nervous system tissue donated for research purposes. The NDBB is committed to advancing the understanding of neurodegenerative disease by performing comprehensive neuropathological characterization of patients who participated in clinical research during life and by providing tissue to leading investigators worldwide.

The Neurodegenerative Disease Brain Bank (NDBB) was established in 2008 and serves as a repository for nervous system tissue donated for research purposes. The NDBB is committed to advancing the understanding of neurodegenerative disease by performing comprehensive neuropathological characterization of patients who participated in clinical research during life and by providing tissue to leading investigators worldwide.

Neurodegenerative Disease Brain Bank Code of Ethics

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