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Gabe Marx

Assistant Clinical Research Coordinator

Gabe grew up in the Bay Area before heading to Ohio to study neuroscience at Oberlin College, graduating in 2014. During his summers, Gabe garnered research experience by working in various neuroscience labs such as Dr. Sofia Vinogradov’s lab at the San Francisco VA researching cognitive training as a therapy for sensory deficits in schizophrenia as well as Dr. Rene Hen’s lab at Columbia University investigating hippocampal neurogenesis in rodent models. Gabe first began his work in neuroimaging while studying abroad in Budapest, Hungary. While working at the Budapest Center for Complex Systems and Computational Neuroscience, Gabe worked on advanced techniques in connectivity analysis of functional MRI data. This work was continued back at Oberlin with his advisor, Dr. Patrick Simen. There, Gabe investigated networks activated in two-point decision making paradigms through fMRI data.

Gabe joined the Memory and Aging Center in September 2014. He is an imaging core analyst and clinical research coordinator for Dr. Rosen’s Neuroimaging in Frontotemporal Dementia study—a longitudinal study aimed at determining which imaging modalities and biomarkers help predict the onset and monitor the progression of frontotemporal dementia.

Gabe currently lives in Oakland. In his free time, Gabe is an active musician and songwriter.

Gallery 190

The Memory and Aging Center has met individuals who never created art before becoming ill and are now making wonderful, intriguing artwork in the face of their illness. When the MAC moved to the UCSF Mission Bay Campus in 2012, we immediately imagined art hanging in the beautiful reception area of Suite 190.

Gallery 190, sponsored by the UCSF Memory and Aging Center (MAC), is located in the Sandler Neurosciences Building on the Mission Bay Campus of the University of California, San Francisco (UCSF).

Queena Lin

Postdoctoral Scholar

Queena (Li-Chun) Lin completed her PhD in neurobiology (Sibille Laboratory of Translational Neuroscience Program, University of Pittsburgh), with a focus on the selective vulnerability of GABAergic interneurons in human and mouse. She joined the Seeley Selective Vulnerability Research Laboratory in September 2014 and is studying the patterns of selective vulnerability in progressive supranuclear palsy and frontotemporal dementia by quantitative neuroanatomy and next generation sequencing.

Nagehan Ayakta

Research Associate

Nagehan graduated from University of California, Berkeley in May 2014 with honors and a bachelor's degree in Molecular and Cell Biology-Neurobiology. She completed her honors thesis at the Jagust laboratory under the guidance of Dr. William Jagust and Dr. Sylvia Villeneuve at the Helen Wills Neuroscience Institute. Her main focus was investigating the temporal and spatial pattern of beta-amyloid accumulation in healthy adults.

At the Memory and Aging Center, Nagehan is a research associate working with Dr. Gil Rabinovici and also continues to work with the Jagust laboratory at Berkeley. Currently she is working on a variety of PET imaging projects studying amyloid, hypometabolism, and tau.

Luke Bonham

Research Coordinator

Luke grew up in Southern California before attending UC Berkeley. Graduating with a degree in business administration, he joined the UC San Francisco Memory and Aging Center in 2013. Prior to joining the Memory and Aging Center, he worked in Dr. Dena Dubal’s lab at UCSF to study sex differences in mouse models of neurodegenerative diseases. He currently works with Jennifer Yokoyama, PhD, and Howard Rosen, MD, to study the genetics of healthy aging and neurodegenerative diseases.

In his free time, Luke likes to ski, camp and hike.

Joanna Hellmuth, MD, MHS

Behavioral Neurology Fellow

Joanna Hellmuth, MD, MHS, joined the UCSF Memory and Aging Center in July 2014 as a behavioral neurology fellow. She provides care to patients with various neurodegenerative disorders and collaborates in the evaluation of patients for the Alzheimer's Disease Research Center (ADRC) and frontotemporal dementia program project grant.

Julio C. Rojas, MD, PhD

Behavioral Neurology Fellow

Julio Rojas received his medical degree from the Tecnológico de Monterrey School of Medicine in Monterrey, Nuevo León, Mexico. He completed his doctoral studies in neuroscience at the University of Texas at Austin with a dissertation on Strategies of neuroprotection in an in vivo model of retinal degeneration induced by mitochondrial dysfunction. He completed neurology residency at UT Southwestern Medical Center in Dallas. In 2014, he joined the UCSF Memory and Aging Center where he is a behavioral neurology fellow. Dr. Rojas is part of the Clinical Trials team led by Dr. Adam Boxer in which he participates in patient evaluation and monitoring. He provides care to patients with various neurodegenerative disorders and collaborates in the evaluation of patients for the Alzheimer's Disease Research Center (ADRC), frontotemporal dementia program project grant and Rapidly Progressive Dementia Program. Dr. Rojas is interested in experimental neurotherapeutics, and his research focuses on biomarker development and cognitive enhancing interventions.

Noelle Ohanesian

Asst. Clinical Research Coordinator

Originally from upstate New York, Noelle graduated from Duke University in May 2014 with a Bachelor of Science degree in neuroscience and a history minor. While attending school, she worked as a research assistant in Duke's Center for Cognitive Neuroscience, running a study examining the effects of acute stress on memory retention. She also spent a summer working for the Behavioral Lab in the Duke University Fuqua School of Business studying social mimicry in anorexic subjects. Outside of her academic interests, she worked as the Program Director of Duke’s backpacking organization, Project WILD, in which she directed one- and two-week backpacking programs for the freshmen class. Noelle joined the UCSF Memory and Aging Center in June 2014 as a member of the clinical trials team under Dr. Adam Boxer. She is a research coordinator for the asymptomatic Alzheimer’s disease trial.

Caitlin Glennon

Analyst

Caitlin joined the Memory and Aging Center in March 2014. She is currently an analyst working on Dr. Boxer’s clinical trials and research studies. She previously worked in the Department of Neurology at UCSF with the Stroke Sciences Group on both industry and NIH-funded clinical trials.

Asymptomatic Alzheimer’s Disease Anti-Amyloid Trial

The purpose of this study is to test whether an investigational drug called solanezumab can slow the progression of memory problems associated with brain amyloid (the protein that forms plaques in the brains of people with Alzheimer’s disease) as compared with placebo in subjects with preclinical AD.

Summary

  • Study director: Adam Boxer, MD, PhD
  • Sponsor: Eli Lilly & Company and National Institute on Aging (NIA)
  • Recruiting?: Yes
  • Official study title: Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4 Study)
  • ClinicalTrials.gov identifier: NCT02008357
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