The LAVA Clinical Research Management System (CRMS) was developed by the UCSF Memory and Aging Center (MAC) to meet the data management needs of a research center with a dynamic and varied set of patient assessment measures and many interrelated research protocols. The system includes a query tool, LAVA Query, which allows principal investigators to create specialized cohorts and generate their own data sets. The system is web-based and can host data for multisite studies.