Assistant Clinical Research Coordinator

November 20, 2019
Neurology – Memory and Aging Center
Full Time
Req Number: 
Under the supervision of a Clinical Research Coordinator (CRC) or Principal Investigator (PI), the Assistant Clinical Research Coordinator will perform entry-level duties related to the support and coordination of multiple projects (e.g., The TabCAT Screen: New Tools to Evaluate Brain Health and Consortium for Detecting Cognitive Impairment, Including Dementia (DetectCID)); coordinate the data collection and operations of concurrent clinical research studies under the guidelines of research protocols, UCSF and regulating agency policies; administer consent forms and standardized test protocols under supervision by a CRC or PI. Any questions that arise during these clinical research visits that go beyond standardized protocol will be escalated to a CRC, Technical Project Manager, or PI.

May help design flow sheets, data forms and source documents; may apply understanding of inclusion/exclusion eligibility criteria for protocols; help recruit, enroll, register, schedule and retain study subjects; assist research personnel to keep patients on study schedules; collect, enter and clean data into study databases, maintaining data quality; assist with data analysis; assist with preparation of reports and tables; attend team meetings; and perform other duties as assigned.
(A) TabCAT Screen. The TabCAT Screen project will provide a decision tree to guide primary care physicians through the steps of the diagnostic and treatment process, not just for Alzheimer’s disease, but also for the non-Alzheimer’s disease dementias, rapidly progressive dementias, and potentially reversible autoimmune dementias. One component of the pathway will include tablet-based cognitive assessments that can be administered in a primary care setting and that include both a brief screen and a more comprehensive test battery. Current brief dementia screens suffer from high false negative rates for patients with mild cognitive impairment or mild dementia, particularly when patients present with a non-memory cognitive impairment as their first symptom (e.g., executive dysfunction, behavioral disturbance). Because of this, many patients who would benefit from a more comprehensive dementia workup are missed. A brief screen that is sensitive to mild neurobehavioral changes and that is easy to use in primary care clinics would help to identify many patients in need of further evaluation.

The intent of the neurobehavioral core is to develop and validate a tablet-based neurobehavioral tool: the Brain Health Assessment, and begin development of the Comprehensive Neurobehavioral Assessment. The aim will be that the tablet-based screen meets recommendations by the Alzheimer’s Association for the Medicare Annual Wellness Visit in primary care and is specifically tailored to be part of the Quest Dementia Care Pathway. Under direction of the PI, the incumbent will collaborate with an interdisciplinary team of neuropsychologists and neurologists; help obtain normative data and repeated cross-sectional administration to different clinical populations; prepare data and images for presentation. The candidate may have the opportunity to interface between the scientific team and a programming team to develop the cognitive tablet-based tests.

(B) DetectCID: The Consortium for Detecting Cognitive Impairment, Including Dementia, is a collaborative network of research programs that are performing cross-site validation of paradigms, tools, and protocols that will increase the frequency, and improve the quality of, patient evaluations for detecting cognitive impairment in primary care and other everyday clinical settings. Up to half of the funded consortium research focuses on paradigms specifically designed to address barriers to detecting cognitive impairment associated with health disparities. The Consortium consists of research teams at UCSF, Albert Einstein College of Medicine, and Northwestern University, with UCSF acting as the Cross-Consortium Coordinating Team (CCCT).
Under direction of the PI, the incumbent will collaborate with an interdisciplinary team of neuropsychologists and neurologists from various institutions, help to manage the Consortium activity, and facilitate Consortium communication. The candidate may have the opportunity to attend Committee meetings.

Throughout the Department of Neurology at UCSF, our mission is to deliver superb patient care, to apply state-of-the-art translational research methods to discover the causes of and treatments for human nervous system disorders, and to educate each generation of medical students, neurology residents and postdoctoral fellows. By fostering cross-disciplinary interactions among scientists around the world, we accelerate the pace of discovery and champion the University’s global health initiatives.

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences.