Victor Valcour, MD, PhD

Professor of Medicine
Executive Director, GBHI
+1 415 476-3746
Fields of Interest

Dr. Valcour is a Professor of Medicine with a shared appointment in the Division of Geriatric Medicine and the Department of Neurology. His work crosses disciplines to research and care for cognitive disorders in aging populations and to understand brain injury in the setting of HIV among all ages, including funded pediatric HIV studies. His clinical work involves consultations for patients with cognitive disorders at the UCSF Memory and Aging Center.

While much of Dr. Valcour's research is completed at UCSF, he has a large international portfolio with many opportunities for junior investigators. Within Southeast Asia, he is Deputy Director of SEARCH/Thailand operating research in acute HIV (within days of infection), pediatric HIV, and markers of dementia in chronic HIV. In Africa, he has partnered with the US Military HIV Research Program to survey cognitive disorders among HIV-infected individuals in Nigeria, Uganda, Kenya, and Tanzania.

Dr. Valcour is broadly involved in mentoring individuals at all levels of training who are interested in clinical research related to cognitive disorders, particularly in association with HIV infection. He has extensive global health experience.

Dr. Valcour’s research interests have two major emphases. He is currently developing a research program that aims to understand optimal care strategies for elders who develop dementia. Nested within the Memory and Aging Center, the long-term goal of this program is to provide model care for elders with cognitive disorders.

Dr. Valcour is internationally recognized for research in cognitive disorders related to HIV. He currently operates 3 NIH R01 series grants within 3 novel cohorts: (1) a chronic HIV infected cohort followed since first initiation of cART; (2) an acute HIV cohort of individuals infected for less than one month at enrollment; (3) and a pediatric cohort in Thailand and Cambodia. He is the Deputy Director of SEARCH/Thailand (www.SEARCHThailand.org). He also operates the UCSF HIV Over 60 Cohort focused on understanding cognitive disorders in the older HIV population living in the San Francisco Bay area. New research will survey of cognitive disorders in HIV for individuals living in Uganda, Kenya, Tanzania and Nigeria.

Dr. Valcour is actively engaged in mentoring individuals wishing to become independent clinical researchers. His research portfolio provides a broad array of local and international projects that can serve as resources for mentored projects. Dr. Valcour serves as an Executive Committee member of the AIDS Research Institute (ARI).

Publications

Social exposome and brain health outcomes of dementia across Latin America.

Migeot J, Pina-Escudero SD, Hernandez H, Gonzalez-Gomez R, Legaz A, Fittipaldi S, Resende EPF, Duran-Aniotz C, Avila-Funes JA, Behrens MI, Bruno MA, Cardona JF, Custodio N, García AM, Godoy ME, Hu K, Lanata S, Lawlor B, Lopera F, Maito MA, Matallana DL, Miller B, Jaime Miranda J, de Oliveira MO, Reyes P, Santamaria-Garcia H, Slachevsky A, Sosa AL, Takada LT, Torres JM, Vanneste S, Valcour V, Wen O, Yokoyama JS, Possin KL, Ibanez A

Genetic Contributions to Alzheimer's Disease and Frontotemporal Dementia in Admixed Latin American Populations.

Acosta-Uribe J, Escudero SDP, Cochran JN, Taylor JW, Castruita A, Jonson C, Barinaga EA, Roberts K, Levine AR, George DS, AvilaFunes JA, Behrens MI, Bruno MA, Brusco LI, Custodio N, Duran-Aniotz C, Lopera F, Matallana DL, Slachevsky A, Takada LT, Zapata-Restrepo LM, Durón-Reyes DE, de Paula França Resende E, Gelvez N, Gómez LF, Godoy ME, Maito MA, Avandel S, Miller BL, Nalls MA, Leonard H, Vitale D, Bandres-Ciga S, Koretsky MJ, Singleton AB, Pantazis CB, Valcour V, Ibañez A, Kosik KS, Yokoyama JS, Bistue MB

Structural inequality linked to brain volume and network dynamics in aging and dementia across the Americas.

Legaz A, Altschuler F, Gonzalez-Gomez R, Hernández H, Baez S, Migeot J, Fittipaldi S, Medel V, Maito MA, Godoy ME, Moguilner S, Cruzat J, Coronel-Oliveros C, Tagliazuchi E, Santamaria Garcia H, Farina FR, Reyes P, Javandel S, García AM, Deleglise Á, Matallana DL, Avila-Funes JA, Slachevsky A, Behrens MI, Custodio N, Trujillo-Llano C, Cardona JF, Barttfeld P, Brusco IL, Bruno MA, Sosa Ortiz AL, Pina-Escudero SD, Takada LT, França Resende EP, Possin KL, Okada de Oliveira M, Hu K, Lopera F, Lawlor B, Valcour V, Yokoyama JS, Miller B, Ibañez A

Author Correction: Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations.

Moguilner S, Baez S, Hernandez H, Migeot J, Legaz A, Gonzalez-Gomez R, Farina FR, Prado P, Cuadros J, Tagliazucchi E, Altschuler F, Maito MA, Godoy ME, Cruzat J, Valdes-Sosa PA, Lopera F, Ochoa-Gómez JF, Hernandez AG, Bonilla-Santos J, Gonzalez-Montealegre RA, Anghinah R, d'Almeida Manfrinati LE, Fittipaldi S, Medel V, Olivares D, Yener GG, Escudero J, Babiloni C, Whelan R, Güntekin B, Yirikogullari H, Santamaria-Garcia H, Lucas AF, Huepe D, Di Caterina G, Soto-Añari M, Birba A, Sainz-Ballesteros A, Coronel-Oliveros C, Yigezu A, Herrera E, Abasolo D, Kilborn K, Rubido N, Clark RA, Herzog R, Yerlikaya D, Hu K, Parra MA, Reyes P, García AM, Matallana DL, Avila-Funes JA, Slachevsky A, Behrens MI, Custodio N, Cardona JF, Barttfeld P, Brusco IL, Bruno MA, Sosa Ortiz AL, Pina-Escudero SD, Takada LT, Resende E, Possin KL, de Oliveira MO, Lopez-Valdes A, Lawlor B, Robertson IH, Kosik KS, Duran-Aniotz C, Valcour V, Yokoyama JS, Miller B, Ibanez A

Dementia risk reduction in the African context: Multi-national implementation of multimodal strategies to promote healthy brain aging in Africa (the Africa-FINGERS project).

Udeh-Momoh CT, Maina R, Anazodo UC, Akinyemi R, Atwoli L, Baker L, Bassil D, Blackmon K, Bosire E, Chemutai G, Crivelli L, Eze LU, Ibanez A, Kafetsouli D, Karikari TK, Khakali L, Kumar M, Lengyel I, de Jager Loots CA, Mangialasche F, Mbugua S, Merali Z, Mielke M, Mostert C, Muthoni E, Nesic-Taylor O, Ngugi A, Nguku S, Ogunniyi A, Ogunyemi A, Okonkwo OC, Okubadejo N, Perneczky R, Peto T, Riang'a RM, Saleh M, Sayed S, Shah J, Shah S, Solomon A, Thesen T, Trepel D, Ucheagwu V, Valcour V, Waa S, Watermeyer T, Yokoyama J, Zetterberg H, Kivipelto M, Africa-FINGERS Study Team

Genetic Contributions to Alzheimer's Disease and Frontotemporal Dementia in Admixed Latin American Populations.

Acosta-Uribe J, Piña Escudero SD, Cochran JN, Taylor JW, Castruita PA, Jonson C, Barinaga EA, Roberts K, Levine AR, George DS, ÁvilaFunes JA, Behrens MI, Bruno MA, Brusco LI, Custodio N, Duran-Aniotz C, Lopera F, Matallana DL, Slachevsky A, Takada LT, Zapata-Restrepo LM, Durón-Reyes DE, de Paula França Resende E, Gelvez N, Godoy ME, Maito MA, Javandel S, Miller BL, Nalls MA, Leonard H, Vitale D, Bandres-Ciga S, Koretsky MJ, Singleton AB, Pantazis CB, Valcour V, Ibañez A, Kosik KS, Yokoyama JS, Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat)

Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations.

Moguilner S, Baez S, Hernandez H, Migeot J, Legaz A, Gonzalez-Gomez R, Farina FR, Prado P, Cuadros J, Tagliazucchi E, Altschuler F, Maito MA, Godoy ME, Cruzat J, Valdes-Sosa PA, Lopera F, Ochoa-Gómez JF, Hernandez AG, Bonilla-Santos J, Gonzalez-Montealegre RA, Anghinah R, d'Almeida Manfrinati LE, Fittipaldi S, Medel V, Olivares D, Yener GG, Escudero J, Babiloni C, Whelan R, Güntekin B, Yirikogullari H, Santamaria-Garcia H, Lucas AF, Huepe D, Di Caterina G, Soto-Añari M, Birba A, Sainz-Ballesteros A, Coronel-Oliveros C, Yigezu A, Herrera E, Abasolo D, Kilborn K, Rubido N, Clark RA, Herzog R, Yerlikaya D, Hu K, Parra MA, Reyes P, García AM, Matallana DL, Avila-Funes JA, Slachevsky A, Behrens MI, Custodio N, Cardona JF, Barttfeld P, Brusco IL, Bruno MA, Sosa Ortiz AL, Pina-Escudero SD, Takada LT, Resende E, Possin KL, de Oliveira MO, Lopez-Valdes A, Lawlor B, Robertson IH, Kosik KS, Duran-Aniotz C, Valcour V, Yokoyama JS, Miller B, Ibanez A

Educational disparities in brain health and dementia across Latin America and the United States.

Gonzalez-Gomez R, Legaz A, Moguilner S, Cruzat J, Hernández H, Baez S, Cocchi R, Coronel-Olivero C, Medel V, Tagliazuchi E, Migeot J, Ochoa-Rosales C, Maito MA, Reyes P, Santamaria Garcia H, Godoy ME, Javandel S, García AM, Matallana DL, Avila-Funes JA, Slachevsky A, Behrens MI, Custodio N, Cardona JF, Brusco IL, Bruno MA, Sosa Ortiz AL, Pina-Escudero SD, Takada LT, Resende EPF, Valcour V, Possin KL, Okada de Oliveira M, Lopera F, Lawlor B, Hu K, Miller B, Yokoyama JS, Gonzalez Campo C, Ibañez A

Brain clocks capture diversity and disparity in aging and dementia.

Moguilner S, Baez S, Hernandez H, Migeot J, Legaz A, Gonzalez-Gomez R, Farina FR, Prado P, Cuadros J, Tagliazucchi E, Altschuler F, Maito MA, Godoy ME, Cruzat J, Valdes-Sosa PA, Lopera F, Ochoa-Gómez JF, Hernandez AG, Bonilla-Santos J, Gonzalez-Montealegre RA, Anghinah R, d'Almeida Manfrinati LE, Fittipaldi S, Medel V, Olivares D, Yener GG, Escudero J, Babiloni C, Whelan R, Güntekin B, Yirikogullari H, Santamaria-Garcia H, Lucas AF, Huepe D, Di Caterina G, Soto-Añari M, Birba A, Sainz-Ballesteros A, Coronel-Oliveros C, Yigezu A, Herrera E, Abasolo D, Kilborn K, Rubido N, Clark RA, Herzog R, Yerlikaya D, Hu K, Parra MA, Reyes P, García AM, Matallana DL, Avila-Funes JA, Slachevsky A, Behrens MI, Custodio N, Cardona JF, Barttfeld P, Brusco IL, Bruno MA, Sosa Ortiz AL, Pina-Escudero SD, Takada LT, Resende E, Possin KL, de Oliveira MO, Lopez-Valdes A, Lawlor B, Robertson IH, Kosik KS, Duran-Aniotz C, Valcour V, Yokoyama JS, Miller BL, Ibanez A

Advancements in dementia research, diagnostics, and care in Latin America: Highlights from the 2023 Alzheimer's Association International conference satellite symposium in Mexico City.

Sosa AL, Brucki SM, Crivelli L, Lopera FJ, Acosta DM, Acosta-Uribe J, Aguilar D, Aguilar-Navarro SG, Allegri RF, Bertolucci PH, Calandri IL, Carrillo MC, Mendez PAC, Cornejo-Olivas M, Custodio N, Damian A, de Souza LC, Duran-Aniotz C, García AM, García-Peña C, Gonzales MM, Grinberg LT, Ibanez AM, Illanes-Manrique MZ, Jack CR, Leon-Salas JM, Llibre-Guerra JJ, Luna-Muñoz J, Matallana D, Miller BL, Naci L, Parra MA, Pericak-Vance M, Piña-Escudero SD, França Resende EP, Ringman JM, Sevlever G, Slachevsky A, Suemoto CK, Valcour V, Villegas-Lanau A, Yassuda MS, Mahinrad S, Sexton C

The 2022 symposium on dementia and brain aging in low- and middle-income countries: Highlights on research, diagnosis, care, and impact.

Kalaria R, Maestre G, Mahinrad S, Acosta DM, Akinyemi RO, Alladi S, Allegri RF, Arshad F, Babalola DO, Baiyewu O, Bak TH, Bellaj T, Brodie-Mends DK, Carrillo MC, Celestin KK, Damasceno A, de Silva RK, de Silva R, Djibuti M, Dreyer AJ, Ellajosyula R, Farombi TH, Friedland RP, Garza N, Gbessemehlan A, Georgiou EE, Govia I, Grinberg LT, Guerchet M, Gugssa SA, Gumikiriza-Onoria JL, Hogervorst E, Hornberger M, Ibanez A, Ihara M, Issac TG, Jönsson L, Karanja WM, Lee JH, Leroi I, Livingston G, Manes FF, Mbakile-Mahlanza L, Miller BL, Musyimi CW, Mutiso VN, Nakasujja N, Ndetei DM, Nightingale S, Novotni G, Nyamayaro P, Nyame S, Ogeng'o JA, Ogunniyi A, de Oliveira MO, Okubadejo NU, Orrell M, Paddick SM, Pericak-Vance MA, Pirtosek Z, Potocnik FCV, Raman R, Rizig M, Rosselli M, Salokhiddinov M, Satizabal CL, Sepulveda-Falla D, Seshadri S, Sexton CE, Skoog I, George-Hyslop PHS, Suemoto CK, Thapa P, Udeh-Momoh CT, Valcour V, Vance JM, Varghese M, Vera JH, Walker RW, Zetterberg H, Zewde YZ, Ismail O

Neuropsychiatric Symptoms and Microglial Activation in Patients with Alzheimer Disease.

Schaffer Aguzzoli C, Ferreira PCL, Povala G, Ferrari-Souza JP, Bellaver B, Soares Katz C, Zalzale H, Lussier FZ, Rohden F, Abbas S, Leffa DT, Scop Medeiros M, Therriault J, Benedet AL, Tissot C, Servaes S, Rahmouni N, Cassa Macedo A, Bezgin G, Kang MS, Stevenson J, Pallen V, Cohen A, Lopez OL, Tudorascu DL, Klunk WE, Villemagne VL, Soucy JP, Zimmer ER, Schilling LP, Karikari TK, Ashton NJ, Zetterberg H, Blennow K, Gauthier S, Valcour V, Miller BL, Rosa-Neto P, Pascoal TA

The Nairobi Declaration-Reducing the burden of dementia in low- and middle-income countries (LMICs): Declaration of the 2022�Symposium on Dementia and Brain Aging in LMICs.

Maestre G, Carrillo M, Kalaria R, Acosta D, Adams L, Adoukonou T, Akinwande K, Akinyemi J, Akinyemi R, Akpa O, Alladi S, Allegri R, Arizaga R, Arshad F, Arulogun O, Babalola D, Baiyewu O, Bak T, Bellaj T, Boshe J, Brayne C, Brodie-Mends D, Brown R, Cahn J, Cyrille N, Damasceno A, de Silva R, de Silva R, Djibuti M, Dreyer AJ, Ellajosyula R, Farombi T, Fongang B, Forner S, Friedland R, Garza N, Gbessemehlan A, Georgiou EE, Gouider R, Govia I, Grinberg L, Guerchet M, Gugssa S, Gumikiriza-Onoria JL, Gustafson D, Hogervorst E, Hornberger M, Ibanez A, Ihara M, Ismail O, Issac T, J?nsson L, Kaputu C, Karanja W, Karungi J, Tshala-Katumbay D, Kunkle B, Lee JH, Leroi I, Lewis R, Livingston G, Lopera F, Lwere K, Manes F, Mbakile-Mahlanza L, Mena P, Miller B, Millogo A, Mohamed A, Musyimi C, Mutiso V, Nakasujja N, Ndetei D, Nightingale S, Njamnshi AK, Novotni G, Nyamayaro P, Nyame S, Ogeng'o J, Ogunniyi A, Okada De Oliveira M, Okubadejo N, Orrell M, Orunmuyi A, Owolabi M, Paddick S, A Pericak-Vance M, Pirtosek Z, Potocnik F, Preston B, Raman R, Ranchod K, Rizig M, Rosselli M, Deepa R, Roy U, Salokhiddinov M, Sano M, Sarfo F, Satizabal CL, Sepulveda-Falla D, Seshadri S, Sexton C, Skoog I, St George-Hyslop P, Suemoto C, Tanner J, Thapa P, Toure K, Ucheagwu V, Udeh-Momoh C, Valcour V, Vance J, Varghese M, Vera J, Walker R, Weidner W, Sebastian W, Whitehead Gay P, Zetterberg H, Zewde Y, African Dementia Consortium

Classification of Alzheimer's disease and frontotemporal dementia using routine clinical and cognitive measures across multicentric underrepresented samples: A cross sectional observational study.

Maito MA, Santamar?a-Garc?a H, Moguilner S, Possin KL, Godoy ME, Avila-Funes JA, Behrens MI, Brusco IL, Bruno MA, Cardona JF, Custodio N, Garc?a AM, Javandel S, Lopera F, Matallana DL, Miller B, de Oliveira MO, Pina-Escudero SD, Slachevsky A, Ortiz ALS, Takada LT, Tagliazuchi E, Valcour V, Yokoyama JS, Iba?ez A

Long-term antiretroviral therapy initiated in acute HIV infection prevents residual dysfunction of HIV-specific CD8+ T cells.

Takata H, Kakazu JC, Mitchell JL, Kroon E, Colby DJ, Sacdalan C, Bai H, Ehrenberg PK, Geretz A, Buranapraditkun S, Pinyakorn S, Intasan J, Tipsuk S, Suttichom D, Prueksakaew P, Chalermchai T, Chomchey N, Phanuphak N, de Souza M, Michael NL, Robb ML, Haddad EK, Crowell TA, Vasan S, Valcour VG, Douek DC, Thomas R, Rolland M, Chomont N, Ananworanich J, Trautmann L, RV254/SEARCH010, RV304/ SEARCH013, and SEARCH011 study groups

Central nervous system safety during brief analytic treatment interruption of antiretroviral therapy within four HIV remission trials: an observational study in acutely treated people living with HIV.

Hellmuth J, Muccini C, Colby DJ, Kroon E, de Souza M, Crowell TA, Chan P, Sacdalan C, Intasan J, Benjapornpong K, Tipsuk S, Puttamaswin S, Chomchey N, Valcour V, Sarnecki M, Tomaka F, Krebs SJ, Slike BM, Jagodzinski LL, Dumrongpisutikul N, Sailasuta N, Samboju V, Michael NL, Robb ML, Vasan S, Ananworanich J, Phanuphak P, Phanuphak N, Paul R, Spudich S

Association of Immunosuppression and Viral Load With Subcortical Brain Volume in an International Sample of People Living With HIV.

Nir TM, Fouche JP, Ananworanich J, Ances BM, Boban J, Brew BJ, Chaganti JR, Chang L, Ching CRK, Cysique LA, Ernst T, Faskowitz J, Gupta V, Harezlak J, Heaps-Woodruff JM, Hinkin CH, Hoare J, Joska JA, Kallianpur KJ, Kuhn T, Lam HY, Law M, Lebrun-Frénay C, Levine AJ, Mondot L, Nakamoto BK, Navia BA, Pennec X, Porges EC, Salminen LE, Shikuma CM, Surento W, Thames AD, Valcour V, Vassallo M, Woods AJ, Thompson PM, Cohen RA, Paul R, Stein DJ, Jahanshad N

Abundant HIV-infected cells in blood and tissues are rapidly cleared upon ART initiation during acute HIV infection.

Leyre L, Kroon E, Vandergeeten C, Sacdalan C, Colby DJ, Buranapraditkun S, Schuetz A, Chomchey N, de Souza M, Bakeman W, Fromentin R, Pinyakorn S, Akapirat S, Trichavaroj R, Chottanapund S, Manasnayakorn S, Rerknimitr R, Wattanaboonyoungcharoen P, Kim JH, Tovanabutra S, Schacker TW, O'Connell R, Valcour VG, Phanuphak P, Robb ML, Michael N, Trautmann L, Phanuphak N, Ananworanich J, Chomont N

Deep Sequencing Reveals Central Nervous System Compartmentalization in Multiple Transmitted/Founder Virus Acute HIV-1 Infection.

Tovanabutra S, Sirijatuphat R, Pham PT, Bonar L, Harbolick EA, Bose M, Song H, Chang D, Oropeza C, O'Sullivan AM, Balinang J, Kroon E, Colby DJ, Sacdalan C, Hellmuth J, Chan P, Prueksakaew P, Pinyakorn S, Jagodzinski LL, Sutthichom D, Pattamaswin S, de Souza M, Gramzinski RA, Kim JH, Michael NL, Robb ML, Phanuphak N, Ananworanich J, Valcour V, Kijak GH, Sanders-Buell E, Spudich S

Acute Retroviral Syndrome is Associated with High Viral Burden, CD4 Depletion, and Immune Activation in Systemic and Tissue Compartments.

Crowell TA, Colby DJ, Pinyakorn S, Fletcher JLK, Kroon E, Schuetz A, Krebs SJ, Slike BM, Leyre L, Chomont N, Jagodzinski LL, Sereti I, Utay NS, Dewar R, Rerknimitr R, Chomchey N, Trichavaroj R, Valcour VG, Spudich S, Michael NL, Robb ML, Phanuphak N, Ananworanich J

Cognitive function and neurodevelopmental outcomes in HIV-infected Children older than 1 year of age randomized to early versus deferred antiretroviral therapy: the PREDICT neurodevelopmental study.

Puthanakit T, Ananworanich J, Vonthanak S, Kosalaraksa P, Hansudewechakul R, van der Lugt J, Kerr SJ, Kanjanavanit S, Ngampiyaskul C, Wongsawat J, Luesomboon W, Vibol U, Pruksakaew K, Suwarnlerk T, Apornpong T, Ratanadilok K, Paul R, Mofenson LM, Fox L, Valcour V, Brouwers P, Ruxrungtham K

Global NeuroAIDS roundtable.

Joseph J, Achim CL, Boivin MJ, Brew BJ, Clifford DB, Colosi DA, Ellis RJ, Heaton RK, Gallo-Diop A, Grant I, Kanmogne GD, Kumar M, Letendre S, Marcotte TD, Nath A, Pardo CA, Paul RH, Pulliam L, Robertson K, Royal W, Sacktor N, Sithinamsuwan P, Smith DM, Valcour V, Wigdahl B, Wood C