Supportive Care Trials
Supportive Care Trials help us evaluate ways to improve the health, care or quality of life for people, typically without using study drugs or devices.

Quality of Life Trials or Supportive Care Trials are research studies to evaluate improving the health, care or quality of life for people, typically without using study drugs or devices. UCSF's Memory and Aging Center (MAC) runs selected supportive trials for people with neurodegenerative disease. Your participation helps us evaluate these interventions. If one of these trials looks interesting to you, please talk with your doctor or contact the study team to see if it is appropriate for you.

Care Ecosystem: Navigating Patients and Families through Stages of Care

Enrollment in the Care Ecosystem study is currently closed for enrollment, but please check back for study updates. The Care Ecosystem is a proactive care model that emphasizes coordinated, continuous, and personalized care to improve the health and satisfaction of patients and their caregivers. The intervention tries to reduce avoidable emergency room visits and hospitalizations, as well as delay entry into a nursing home.

A paper in the scientific journal PLoS describes the trial: Possin, Merrilees, Bonasera, et al 2017.

If you are interested in developing the Care Ecosystem program at your institution, please see our page on Building a Care Ecosystem.

Life Enhancing Activities for Family Caregivers (LEAF)

The LEAF study is now closed for enrollment, and the results were published in May 2019. The purpose of this study is to learn more about how a behavioral intervention that aims to increase positive affect can affect stress level, improve mood, and lessen the perceived burden of family caregiving for those who care for a person with dementia.