Christine Walsh, PhD

Associate Professor
+1 415 476-8676
Fields of Interest

Christine M. Walsh, PhD, is an associate professor in the Department of Neurology at UCSF and a leading researcher in sleep and circadian rhythms, with a focus on aging and neurodegenerative diseases. She investigates the effects of changes in sleep and circadian rhythms on cognitive health, neurological function, and overall well-being in older adults.

Dr. Walsh earned her bachelor’s degree in human physiology from Trinity College Dublin, University of Dublin in Ireland, and her PhD in neuroscience from the University of Michigan. During her doctoral studies, she examined the effects of REM sleep modulation on learning and memory, as well as the neural correlates of cognitive aging. In 2011, she joined the UCSF Edward and Pearl Fein Memory and Aging Center, where she established a sleep research program to study sleep disturbances in healthy aging and individuals with neurodegenerative diseases.

An expert in using advanced techniques such as EEG, polysomnography, actigraphy, and wearable devices, Dr. Walsh has extensive experience in designing and conducting clinical trials. She currently oversees multiple trials stemming from observational research, aiming to improve sleep quality and overall health in aging populations.

Dr. Walsh is passionate about mentoring the next generation of scientists and clinicians. She has taught neuroscience courses at the University of Michigan and San Francisco State University, and her outreach efforts include community programs to educate the public about sleep health in aging populations. She is also the co-founder and COO of the Advanced Science Exploratory Program, a nonprofit organization that works with individuals and schools to mentor, educate, and support future researchers, therapists, and doctors.

Publications

Are noradrenergic and orexinergic systems contributing to sleep-wake patterns in early and late-onset Alzheimer’s Disease?.

Neus Falgàs Martínez, Emma Muñoz-Moreno, Gerard Mayà, Amaia Muñoz-Lopetegui, Paula Marrero-González, Andrea Val-Guardiola, Núria Guillén, Jordi Sarto, Beatriz Bosch, Mircea Balasa, Guadalupe Fernandez-Villullas, Anna Antonell, Christine M Walsh, Leslie Ruoff, Santamaria Joan, Núria Bargalló, Albert Lladó, Manuel Morales-Ruiz, Álex Iranzo, Lea T. Grinberg, Raquel Sanchez-Valle

Deciphering the molecular signature of selective neuronal vulnerability in the wake-promoting lateral hypothalamic area in Alzheimer’s disease: A digital multiplexed gene expression study across Braak stages.

Abhijit Satpati, Felipe Luiz Pereira, Alexander Soloviev, Mihovil Mladinov, Renata Elaine Paraizo Leite, Claudia Kimie Suemoto, Roberta Diehl Rodriguez, Vitor Ribeiro Paes, Christine M Walsh, Salvatore Spina, William W. Seeley, Carlos Augusto Pasquallucci, Wilson Jacob-Filho, Thomas C. Neylan, Lea T. Grinberg

Patient-Derived Cancer Organoid Cultures to Predict Sensitivity to Chemotherapy and Radiation.

Pasch CA, Favreau PF, Yueh AE, Babiarz CP, Gillette AA, Sharick JT, Karim MR, Nickel KP, DeZeeuw AK, Sprackling CM, Emmerich PB, DeStefanis RA, Pitera RT, Payne SN, Korkos DP, Clipson L, Walsh CM, Miller D, Carchman EH, Burkard ME, Lemmon KK, Matkowskyj KA, Newton MA, Ong IM, Bassetti MF, Kimple RJ, Skala MC, Deming DA

ABCA transporter gene expression and poor outcome in epithelial ovarian cancer.

Hedditch EL, Gao B, Russell AJ, Lu Y, Emmanuel C, Beesley J, Johnatty SE, Chen X, Harnett P, George J, Australian Ovarian Cancer Study Group, Williams RT, Flemming C, Lambrechts D, Despierre E, Lambrechts S, Vergote I, Karlan B, Lester J, Orsulic S, Walsh C, Fasching P, Beckmann MW, Ekici AB, Hein A, Matsuo K, Hosono S, Nakanishi T, Yatabe Y, Pejovic T, Bean Y, Heitz F, Harter P, du Bois A, Schwaab I, Hogdall E, Kjaer SK, Jensen A, Hogdall C, Lundvall L, Engelholm SA, Brown B, Flanagan J, Metcalf MD, Siddiqui N, Sellers T, Fridley B, Cunningham J, Schildkraut J, Iversen E, Weber RP, Berchuck A, Goode E, Bowtell DD, Chenevix-Trench G, deFazio A, Norris MD, MacGregor S, Haber M, Henderson MJ