Gowoon Son

Gowoon Son, PhD

Postdoctoral Scholar
[email protected]
Fields of Interest: 
Pathology

Dr. Gowoon Son is a molecular and cellular neuroscientist and received her PhD degree from Maastricht University in the Netherlands and DGIST in South Korea in 2021. Her doctoral work focused on the neuropathology of Alzheimer’s disease in the olfactory system. She identified the olfactory sensory neurons that generate amyloid-beta protein, which causes anosmia in Alzheimer’s disease, by using both genetically modified mouse models and human tissues. In addition, she discovered a potential non-invasive biomarker using human nasal fluid. Her previous exploration of the early symptoms and onset mechanism of Alzheimer’s disease inspired Gowoon to join the Grinberg Lab in September 2021, where she is investigating a mechanism of sleep disturbances in tau-driven pathology in subcortical and brainstem nuclei in Alzheimer’s and other neurodegenerative diseases.

Publications: 

Priorities for research on neuromodulatory subcortical systems in Alzheimer's disease: Position paper from the NSS PIA of ISTAART.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Ehrenberg AJ, Kelberman MA, Liu KY, Dahl MJ, Weinshenker D, Falgàs N, Dutt S, Mather M, Ludwig M, Betts MJ, Winer JR, Teipel S, Weigand AJ, Eschenko O, Hämmerer D, Leiman M, Counts SE, Shine JM, Robertson IH, Levey AI, Lancini E, Son G, Schneider C, Egroo MV, Liguori C, Wang Q, Vazey EM, Rodriguez-Porcel F, Haag L, Bondi MW, Vanneste S, Freeze WM, Yi YJ, Maldinov M, Gatchel J, Satpati A, Babiloni C, Kremen WS, Howard R, Jacobs HIL, Grinberg LT

Refined prefrontal working memory network as a neuromarker for Alzheimer's disease.

Biomedical optics express

Kim E, Yu JW, Kim B, Lim SH, Lee SH, Kim K, Son G, Jeon HA, Moon C, Sakong J, Choi JW

Severe histomorphological alterations in post-mortem olfactory glomeruli in Alzheimer's disease.

Brain pathology (Zurich, Switzerland)

Son G, Steinbusch HWM, López-Iglesias C, Moon C, Jahanshahi A

Olfactory neuropathology in Alzheimer's disease: a sign of ongoing neurodegeneration.

BMB reports

Son G, Jahanshahi A, Yoo SJ, Boonstra JT, Hopkins DA, Steinbusch HWM, Moon C

Region-specific amyloid-β accumulation in the olfactory system influences olfactory sensory neuronal dysfunction in 5xFAD mice.

Alzheimer's research & therapy

Son G, Yoo SJ, Kang S, Rasheed A, Jung DH, Park H, Cho B, Steinbusch HWM, Chang KA, Suh YH, Moon C

Longitudinal profiling of oligomeric Aβ in human nasal discharge reflecting cognitive decline in probable Alzheimer's disease.

Scientific reports

Yoo SJ, Son G, Bae J, Kim SY, Yoo YK, Park D, Baek SY, Chang KA, Suh YH, Lee YB, Hwang KS, Kim Y, Moon C

Distinct amyloid precursor protein processing machineries of the olfactory system.

Biochemical and biophysical research communications

Kim JY, Rasheed A, Yoo SJ, Kim SY, Cho B, Son G, Yu SW, Chang KA, Suh YH, Moon C

The erythropoietin-derived peptide MK-X and erythropoietin have neuroprotective effects against ischemic brain damage.

Cell death & disease

Yoo SJ, Cho B, Lee D, Son G, Lee YB, Soo Han H, Kim E, Moon C, Moon C