Rowan Saloner, PhD

Assistant Professor
Fields of Interest: 

Dr. Saloner is a scientist-practitioner and Assistant Professor at the UCSF Memory and Aging Center. His research integrates deep molecular screening tools, including large-scale proteomics platforms and targeted biomarker assays, with longitudinal clinical phenotyping to discover molecular pathways and biomarker candidates that drive the earliest clinical manifestations of neurodegenerative disease. Dr. Saloner obtained his PhD in Clinical Psychology from the UCSD/SDSU Joint Doctoral Program and completed his fellowship in Neuropsychology at UCSF.

Publications: 

Better cardiovascular health is associated with slowed clinical progression in autosomal dominant frontotemporal lobar degeneration variant carriers.

Alzheimer's & dementia : the journal of the Alzheimer's Association

VandeBunte AM, Lee H, Paolillo EW, Hsiung GR, Staffaroni AM, Saloner R, Tartaglia C, Yaffe K, Knopman DS, Ramos EM, Rascovsky K, Bozoki AC, Wong B, Domoto-Reilly K, Snyder A, Pressman P, Mendez MF, Litvan I, Fields JA, Galasko DR, Darby R, Masdeu JC, Pasqual MB, Honig LS, Ghoshal N, Appleby BS, Mackenzie IR, Heuer HW, Kramer JH, Boxer AL, Forsberg LK, Boeve B, Rosen HJ, Casaletto KB, ALLFTD Consortium

Predicting brain atrophy and cognitive aging trajectories with baseline subjective cognitive concerns in cognitively normal older adults.

Neurobiology of aging

You M, Lindbergh CA, La Joie R, Paolillo EW, Saloner R, Diaz V, Cotter DL, Walters S, Altendahl M, Staffaroni AM, Kramer JH, Gaynor LS, Casaletto KB

Examining Associations Between Smartphone Use and Clinical Severity in Frontotemporal Dementia: Proof-of-Concept Study.

JMIR aging

Paolillo EW, Casaletto KB, Clark AL, Taylor JC, Heuer HW, Wise AB, Dhanam S, Sanderson-Cimino M, Saloner R, Kramer JH, Kornak J, Kremers W, Forsberg L, Appleby B, Bayram E, Bozoki A, Brushaber D, Darby RR, Day GS, Dickerson BC, Domoto-Reilly K, Elahi F, Fields JA, Ghoshal N, Graff-Radford N, G H Hall M, Honig LS, Huey ED, Lapid MI, Litvan I, Mackenzie IR, Masdeu JC, Mendez MF, Mester C, Miyagawa T, Naasan G, Pascual B, Pressman P, Ramos EM, Rankin KP, Rexach J, Rojas JC, VandeVrede L, Wong B, Wszolek ZK, Boeve BF, Rosen HJ, Boxer AL, Staffaroni AM, ALLFTD Consortium

Associations of cerebrovascular disease and Alzheimer's disease pathology with cognitive decline: Analysis of the National Alzheimer's Coordinating Center Uniform Data Set.

Neurobiology of aging

Chatterjee A, Lee S, Diaz V, Saloner R, Sanderson-Cimino M, deCarli C, Maillard P, Hinman J, Vossel K, Casaletto KB, Staffaroni AM, Paolillo EW, Kramer JH

Unveiling the proteome-wide autoreactome enables enhanced evaluation of emerging CAR-T therapies in autoimmunity.

The Journal of clinical investigation

Bodansky A, Yu DJ, Rallistan AN, Kalaycioglu M, Boonyaratanakornkit J, Green DJ, Gauthier J, Turtle CJ, Zorn KC, O'Donovan B, Mandel-Brehm C, Asaki J, Kortbawi H, Kung AF, Rackaityte E, Wang CY, Saxena A, de Dios K, Masi G, Nowak RJ, O'Connor KC, Li H, Diaz VE, Saloner R, Casaletto KB, Gontrum EQ, Chan BJ, Kramer JH, Wilson MR, Utz PJ, Hill JA, Jackson SW, Anderson MS, DeRisi JL

Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration.

Research square

Saloner R, Staffaroni A, Dammer E, Johnson ECB, Paolillo E, Wise A, Heuer H, Forsberg L, Lago AL, Webb J, Vogel J, Santillo A, Hansson O, Kramer J, Miller B, Li J, Loureiro J, Sivasankaran R, Worringer K, Seyfried N, Yokoyama J, Seeley W, Spina S, Grinberg L, VandeVrede L, Ljubenkov P, Bayram E, Bozoki A, Brushaber D, Considine C, Day G, Dickerson B, Domoto-Reilly K, Faber K, Galasko D, Geschwind D, Ghoshal N, Graff-Radford N, Hales C, Honig L, Hsiung GY, Huey E, Kornak J, Kremers W, Lapid M, Lee S, Litvan I, McMillan C, Mendez M, Miyagawa T, Pantelyat A, Pascual B, Paulson H, Petrucelli L, Pressman P, Ramos E, Rascovsky K, Roberson E, Savica R, Snyder A, Sullivan AC, Tartaglia C, Vandebergh M, Boeve B, Rosen H, Rojas J, Boxer A, Casaletto K

Neuropsychiatric profiles and cerebral amyloid burden in adults without dementia.

Dementia and geriatric cognitive disorders

Gontrum EQ, Paolillo EW, Lee S, Diaz V, Ehrenberg A, Saloner R, Mundada NS, La Joie R, Rabinovici G, Kramer JH, Casaletto K

KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.

The Journal of clinical investigation

Kauwe G, Pareja-Navarro KA, Yao L, Chen JH, Wong I, Saloner R, Cifuentes H, Nana AL, Shah S, Li Y, Le D, Spina S, Grinberg LT, Seeley WW, Kramer JH, Sacktor TC, Schilling B, Gan L, Casaletto KB, Tracy TE

Latent Profile Analysis of Cognitive Performance and Depressive Symptoms Among People with HIV.

AIDS patient care and STDs

Kohli M, Ham L, Saloner R, Dung D, Iudicello J, Ellis RJ, Moore DJ

Multimodal lifestyle engagement patterns support cognitive stability beyond neuropathological burden.

Alzheimer's research & therapy

Paolillo EW, Saloner R, VandeBunte A, Lee S, Bennett DA, Casaletto KB

The clinical utility of three frailty measures in identifying HIV-associated neurocognitive disorders.

AIDS (London, England)

Moore DJ, Sun-Suslow N, Nichol AA, Paolillo EW, Saloner R, Letendre SL, Iudicello J, Morgan EE

Plasma phosphorylated tau-217 exhibits sex-specific prognostication of cognitive decline and brain atrophy in cognitively unimpaired adults.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Saloner R, VandeVrede L, Asken BM, Paolillo EW, Gontrum EQ, Wolf A, Lario-Lago A, Milà-Alomà M, Triana-Baltzer G, Kolb HC, Dubal DB, Rabinovici GD, Miller BL, Boxer AL, Casaletto KB, Kramer JH

Moderating role of physical activity on hippocampal iron deposition and memory outcomes in typically aging older adults.

Neurobiology of aging

Lee SY, Paolillo EW, Saloner R, Cobigo Y, Diaz VE, Gontrum EQ, VandeBunte A, Chatterjee A, Tucker M, Kramer JH, Casaletto KB

KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.

bioRxiv : the preprint server for biology

Kauwe G, Pareja-Navarro KA, Yao L, Chen JH, Wong I, Saloner R, Cifuentes H, Nana AL, Shah S, Li Y, Le D, Spina S, Grinberg LT, Seeley WW, Kramer JH, Sacktor TC, Schilling B, Gan L, Casaletto KB, Tracy TE

Data-driven physical actigraphy patterns relate to cognitive and vascular health in older adults.

Experimental gerontology

Paolillo EW, Lee SY, VandeBunte A, Saloner R, Gaynor LS, Djukic N, Tsuei T, Cobigo Y, Kramer JH, Casaletto KB

Sex-specific effects of SNAP-25 genotype on verbal memory and Alzheimer's disease biomarkers in clinically normal older adults.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Saloner R, Paolillo EW, Wojta KJ, Fonseca C, Gontrum EQ, Lario-Lago A, Rabinovici GD, Yokoyama JS, Rexach JE, Kramer JH, Casaletto KB

Sex Differences in the Relationship between Perceived Stress and Cognitive Trajectories.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Paolillo EW, You M, Gontrum E, Saloner R, Gaynor LS, Kramer JH, Casaletto KB

Combined Effects of Synaptic and Axonal Integrity on Longitudinal Gray Matter Atrophy in Cognitively Unimpaired Adults.

Neurology

Saloner R, Fonseca C, Paolillo EW, Asken BM, Djukic NA, Lee S, Nilsson J, Brinkmalm A, Blennow K, Zetterberg H, Kramer JH, Casaletto KB

Plasma biomarkers of vascular dysfunction uniquely relate to a vascular-risk profile of neurocognitive deficits in virally-suppressed adults with HIV.

Brain, behavior, & immunity - health

Saloner R, Sun-Suslow N, Morgan EE, Lobo J, Cherner M, Ellis RJ, Heaton RK, Grant I, Letendre SL, Iudicello JE, TMARC Group

Cognitive and Physiologic Reserve Independently Relate to Superior Neurocognitive Abilities in Adults Aging With HIV.

Journal of acquired immune deficiency syndromes (1999)

Saloner R, Lobo JD, Paolillo EW, Campbell LM, Letendre SL, Cherner M, Grant I, Heaton RK, Ellis RJ, Moore DJ, CHARTER Study Group

Higher Comorbidity Burden Predicts Worsening Neurocognitive Trajectories in People with Human Immunodeficiency Virus.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Ellis RJ, Paolillo E, Saloner R, Heaton RK

The association between benzodiazepine use and greater risk of neurocognitive impairment is moderated by medical burden in people with HIV.

Journal of neurovirology

Sundermann EE, Saloner R, Rubtsova A, Nguyen AL, Letendre S, Moore RC, Cherner M, Ma Q, Marquine MJ

Neopterin Relates to Lifetime Depression in Older Adults With HIV on Suppressive Antiretroviral Therapy.

Journal of acquired immune deficiency syndromes (1999)

Saloner R, Savini N, Letendre SL, Moore DJ, Montoya JL

Relationship of the balloon analog risk task to neurocognitive impairment differs by HIV serostatus and history of major depressive disorder.

Journal of neurovirology

Saloner R, Morgan EE, Hussain MA, Moore DJ, Heaton RK, Cherner M, Grant I, Iudicello JE, TMARC Group

Frailty Syndrome Is Associated with Poorer Self-Reported Sleep Quality Among Older Persons with Human Immunodeficiency Virus.

AIDS research and human retroviruses

Sun-Suslow N, Balon E, Montoya JL, Saloner R, Campbell LM, Serrano V, Ellis RJ, Moore DJ

Identification of Youthful Neurocognitive Trajectories in Adults Aging with HIV: A Latent Growth Mixture Model.

AIDS and behavior

Saloner R, Lobo JD, Paolillo EW, Campbell LM, Letendre SL, Cherner M, Grant I, Heaton RK, Ellis RJ, Roesch SC, Moore DJ, CHARTER Study Group

Binge Drinking Relates to Worse Neurocognitive Functioning Among Adults Aging with HIV.

Journal of the International Neuropsychological Society : JINS

Paolillo EW, Saloner R, Kohli M, Watson CW, Moore RC, Heaton RK, Moore DJ

A Cross-Sectional Study to Evaluate the Effects of Age and Duration of HIV Infection on Anxiety and Depression in Cisgender Men.

AIDS and behavior

Gianella S, Saloner R, Curtin G, Little SJ, Heaton A, Montoya JL, Letendre SL, Marquine MJ, Jeste DV, Moore DJ

The utility of olfactory function in distinguishing early-stage Alzheimer's disease from HIV-associated neurocognitive disorders.

AIDS (London, England)

Sundermann EE, Fields A, Saloner R, Gouaux B, Bharti A, Murphy C, Moore DJ

Telomere length is associated with HIV infection, methamphetamine use, inflammation, and comorbid disease risk.

Drug and alcohol dependence

Mehta SR, Iudicello JE, Lin J, Ellis RJ, Morgan E, Okwuegbuna O, Cookson D, Karris M, Saloner R, Heaton R, Grant I, Letendre S, TMARC Group

Metabolic Risk Factors as Differential Predictors of Profiles of Neurocognitive Impairment Among Older HIV+ and HIV- Adults: An Observational Study.

Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

Pasipanodya EC, Montoya JL, Campbell LM, Hussain MA, Saloner R, Paolillo EM, Jeste DV, Letendre SL, McCutchan JA, Heaton RK, Moore DJ

Chronically elevated depressive symptoms interact with acute increases in inflammation to predict worse neurocognition among people with HIV.

Journal of neurovirology

Saloner R, Paolillo EW, Heaton RK, Grelotti DJ, Stein MB, Miller AH, Atkinson JH, Letendre SL, Ellis RJ, Grant I, Iudicello JE, Moore DJ

Lifetime Methamphetamine Use Disorder and Reported Sleep Quality in Adults Living with HIV.

AIDS and behavior

Sun-Suslow N, Saloner R, Serrano V, Umlauf A, Morgan EE, Ellis RJ, Letendre S, Grant I, Heaton RK

Cerebrospinal Fluid Norepinephrine and Neurocognition in HIV and Methamphetamine Dependence.

Journal of acquired immune deficiency syndromes (1999)

Saloner R, Cherner M, Iudicello JE, Heaton RK, Letendre SL, Ellis RJ

Lower CSF homovanillic acid relates to higher burden of neuroinflammation and depression in people with HIV disease.

Brain, behavior, and immunity

Saloner R, Cherner M, Grelotti DJ, Paolillo EW, Moore DJ, Heaton RK, Letendre SL, Kumar A, Grant I, Ellis RJ

Methamphetamine and Cannabis: A Tale of Two Drugs and their Effects on HIV, Brain, and Behavior.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

Saloner R, Fields JA, Marcondes MCG, Iudicello JE, von Känel S, Cherner M, Letendre SL, Kaul M, Grant I, Translational Methamphetamine AIDS Research Center (TMARC) Group

REM sleep is associated with white matter integrity in cognitively healthy, older adults.

PloS one

Altendahl M, Cotter DL, Staffaroni AM, Wolf A, Mumford P, Cobigo Y, Casaletto K, Elahi F, Ruoff L, Javed S, Bettcher BM, Fox E, You M, Saloner R, Neylan TC, Kramer JH, Walsh CM

COMT val158met genotype alters the effects of methamphetamine dependence on dopamine and dopamine-related executive function: preliminary findings.

Psychiatry research

Saloner R, Cherner M, Sundermann EE, Watson CW, Iudicello JE, Letendre SL, Kumar A, Ellis RJ

The Effects of Low-Risk Drinking on Neurocognition Among Older Persons Living With HIV as Compared to Those Without HIV.

Alcoholism, clinical and experimental research

Kohli M, Paolillo EW, Saloner R, Umlauf A, Ellis R, Moore DJ

Benzodiazepine Use Is Associated With an Increased Risk of Neurocognitive Impairment in People Living With HIV.

Journal of acquired immune deficiency syndromes (1999)

Saloner R, Grelotti DJ, Tyree G, Sundermann EE, Ma Q, Letendre S, Heaton RK, Cherner M

Use of Neuroimaging to Inform Optimal Neurocognitive Criteria for Detecting HIV-Associated Brain Abnormalities.

Journal of the International Neuropsychological Society : JINS

Campbell LM, Fennema-Notestine C, Saloner R, Hussain M, Chen A, Franklin D, Umlauf A, Ellis RJ, Collier AC, Marra CM, Clifford DB, Gelman BB, Sacktor N, Morgello S, McCutchan JA, Letendre S, Grant I, Heaton RK, CHARTER Group

COMT Val158Met Polymorphism, Cardiometabolic Risk, and Nadir CD4 Synergistically Increase Risk of Neurocognitive Impairment in Men Living With HIV.

Journal of acquired immune deficiency syndromes (1999)

Saloner R, Marquine MJ, Sundermann EE, Hong S, McCutchan JA, Ellis RJ, Heaton RK, Grant I, Cherner M

Frailty in Comorbid HIV and Lifetime Methamphetamine Use Disorder: Associations with Neurocognitive and Everyday Functioning.

AIDS research and human retroviruses

Paolillo EW, Saloner R, Montoya JL, Campbell LM, Pasipanodya EC, Iudicello JE, Moore RC, Letendre SL, Jeste DV, Moore DJ

Adverse effect of catechol-O-methyltransferase (COMT) Val158Met met/met genotype in methamphetamine-related executive dysfunction.

Addictive behaviors

Cherner M, Watson CW, Saloner R, Halpin LE, Minassian A, Murray SS, Vaida F, Bousman C, Everall I, TMARC Group

Conditional Effects of Lifetime Alcohol Consumption on Methamphetamine-Associated Neurocognitive Performance.

Journal of the International Neuropsychological Society : JINS

Saloner R, Paolillo EW, Umlauf A, Moore DJ, Heaton RK, Grant I, Cherner M, TMARC Group

Effects of comorbidity burden and age on brain integrity in HIV.

AIDS (London, England)

Saloner R, Heaton RK, Campbell LM, Chen A, Franklin D, Ellis RJ, Collier AC, Marra C, Clifford DB, Gelman B, Sacktor N, Morgello S, McCutchan JA, Letendre S, Grant I, Fennema-Notestine C, CHARTER Study Group

Neurocognitive SuperAging in Older Adults Living With HIV: Demographic, Neuromedical and Everyday Functioning Correlates.

Journal of the International Neuropsychological Society : JINS

Saloner R, Campbell LM, Serrano V, Montoya JL, Pasipanodya E, Paolillo EW, Franklin D, Ellis RJ, Letendre SL, Collier AC, Clifford DB, Gelman BB, Marra CM, McCutchan JA, Morgello S, Sacktor N, Jeste DV, Grant I, Heaton RK, Moore DJ, CHARTER and HNRP Groups

Age of Last Alcohol Use Disorder Relates to Processing Speed Among Older Adults Living with HIV.

Alcohol and alcoholism (Oxford, Oxfordshire)

Paolillo EW, Inkelis SM, Heaton A, Saloner R, Moore RC, Moore DJ

Increases in a Pro-inflammatory Chemokine, MCP-1, Are Related to Decreases in Memory Over Time.

Frontiers in aging neuroscience

Bettcher BM, Neuhaus J, Wynn MJ, Elahi FM, Casaletto KB, Saloner R, Fitch R, Karydas A, Kramer JH

Neurocognitive impairment with hepatitis C and HIV co-infection in Southern Brazil.

Journal of neurovirology

de Almeida SM, de Pereira AP, Pedroso MLA, Ribeiro CE, Rotta I, Tang B, Umlauf A, Franklin D, Saloner RG, Batista MGR, Letendre S, Heaton RK, Ellis RJ, Cherner M, HNRC Group

The Longitudinal Trajectory of Default Mode Network Connectivity in Healthy Older Adults Varies As a Function of Age and Is Associated with Changes in Episodic Memory and Processing Speed.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Staffaroni AM, Brown JA, Casaletto KB, Elahi FM, Deng J, Neuhaus J, Cobigo Y, Mumford PS, Walters S, Saloner R, Karydas A, Coppola G, Rosen HJ, Miller BL, Seeley WW, Kramer JH

HIV-Associated Neurocognitive Disorders: A Global Perspective.

Journal of the International Neuropsychological Society : JINS

Saloner R, Cysique LA

Performance on a 1-week delayed recall task is associated with medial temporal lobe structures in neurologically normal older adults.

The Clinical neuropsychologist

Saloner R, Casaletto KB, Marx G, Dutt S, Vanden Bussche AB, You M, Fox E, Stiver J, Kramer JH

Long-term test-retest reliability of the California Verbal Learning Test - second edition.

The Clinical neuropsychologist

Alioto AG, Kramer JH, Borish S, Neuhaus J, Saloner R, Wynn M, Foley JM