Maryana Alegro Ribeiro, PhD

Postdoctoral Fellow
+1 415 502-7174
Fields of Interest: 

Dr. Alegro joined the Grinberg lab in 2015, where she uses her knowledge in image and signal processing for building computational tools to help improve the understanding of neurodegenerative diseases. She also works in building and testing prototype imaging equipment for the lab. Her major experience is in MRI and histological image processing and, more recently, polarized light imaging. Dr. Alegro received her MSc in electrical engineering from the University of São Paulo Polytechnic School in 2009, where she focused on MRI brain tumor segmentation using machine learning. In 2014 she completed her PhD degree at the University of São Paulo Polytechnic School, her research focused on MRI and histology image registration. Dr. Alegro also has a long experience as enterprise software developer, having worked on the development of several medical systems for the Brazilian government.


High thickness histological sections as alternative to study the three-dimensional microscopic human sub-cortical neuroanatomy.

Brain structure & function

Alho EJL, Alho ATDL, Grinberg L, Amaro E, Dos Santos GAB, da Silva RE, Neves RC, Alegro M, Coelho DB, Teixeira MJ, Fonoff ET, Heinsen H

Proceedings of the Practice and Experience in Advanced Research Computing 2017 on Sustainability, Success and Impact

Portable Learning Environments for Hands-On Computational Instruction: Using Container- and Cloud-Based Technology to Teach Data Science

Holdgraf, C; Culich, A; Rokem, A; Deniz, F; Alegro, M; Ushuzima, D;

Magnetic resonance diffusion tensor imaging for the pedunculopontine nucleus: proof of concept and histological correlation.

Brain structure & function

Alho ATDL, Hamani C, Alho EJL, da Silva RE, Santos GAB, Neves RC, Carreira LL, Araújo CMM, Magalhães G, Coelho DB, Alegro MC, Martin MGM, Grinberg LT, Pasqualucci CA, Heinsen H, Fonoff ET, Amaro E

Automating cell detection and classification in human brain fluorescent microscopy images using dictionary learning and sparse coding.

Journal of neuroscience methods

Alegro M, Theofilas P, Nguy A, Castruita PA, Seeley W, Heinsen H, Ushizima DM, Grinberg LT

Multimodal Whole Brain Registration: MRI and High Resolution Histology

IEEE Conference on Computer Vision and Pattern Recognition (CVPR) WBIR

Alegro, M; Amaro-Jr, E; Loring B; Heinsen, H; Alho, E; Zollei, L; Ushizima, Daniela; Grinberg, LT

A computational pipeline for full brain histology to mri registration


Alegro MC, Alho E, Lopes RD, Zollei L, Amaro-Jr E

Neuropathological biomarkers of human refractory temporal lobe epilepsy associated with hippocampal sclerosis: Clinical and neuroimaging correlations

Epilepsy & Behavior

Pimentel-Silva LR; Alegro MC; Bando SY; Caetano NC; Santos PF; Rosa FO; Hatano VY; Toma MA; Castro LHM; Hung-Tzu W; Amaro E; Moreira-Filho CA; Silva AV

Cognition and cerebral neurovascular coupling in the elderly with metabolic syndrome

Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Shigaeff N; Jacinto A; Chiochetta G; Cendoroglo MS; Amaro E; Ikeda M; Alegro M; Gazelato F; Citero V

Texture analysis of high resolution MRI allows discrimination between febrile and afebrile initial precipitating injury in mesial temporal sclerosis.

Magnetic resonance in medicine

de Carvalho Alegro M, Valotta Silva A, Yumi Bando S, de Deus Lopes R, Martins de Castro LH, Hungtsu W, Moreira-Filho CA, Amaro E

Hippocampal CA3 transcriptome signature correlates with initial precipitating injury in refractory mesial temporal lobe epilepsy.

PloS one

Bando SY, Alegro MC, Amaro E, Silva AV, Castro LH, Wen HT, Lima Lde A, Brentani H, Moreira-Filho CA


Cytoarchitectural abnormalities of the dentate gyrus in refractory medial temporal lobe epilepsy

Silva AV; Silva LRP; Bando SY; Alegro MC; Amaro E; Castro LHM; Hung-Tzu W; Moreira CA


High resolution mri texture analysis of hippocampal tissue: histopathological correlations in mesial temporal lobe epilepsy

Alegro MC; Amaro E; Silva AV; Bando SY; Lopes RD; Moreira-Filho CA


Hippocampal CA3 transcriptome signature and dentate gyrus MRI features correlate with initial precipitating injury in refractory temporal lobe epilepsy

Bando SY; Alegro MC; Amaro-Jr E; Silva AV; Castro LH; Wen HT; Lima LA; Brentani, Helena, Moreira-Filho CA

Texture Analysis of Hippocampal Sclerosis in High Resolution MRI: Preliminary Results


Alegro MC, Lopes RD, Medeiros BC, Gonçalves AS, Silva AV, Amaro-Jr E

A Web-based system for the consolidation of hospital-based cancer registries in Brazil

Journal of Telemedicine and Telecare

Moretto EG, Alegro MC, Mello AN, Kondo MNS, Camanho PA, Zuffo MK