Winston Chiong, MD, PhD

Associate Professor
Neurology
+1 415 502-7326
Fields of Interest: 

Dr. Winston Chiong is an Associate Professor in the UCSF Department of Neurology Memory and Aging Center, and is principal investigator of the UCSF Decision Lab. His clinical practice focuses on Alzheimer’s disease, frontotemporal dementia and other cognitive disorders of aging. His research has two main themes:

  1. the neural bases of decision-making in the aging brain, focusing on how brain systems involved in financial and medical decisions are influenced by health and disease; and
  2. the ethical and policy implications of alterations to brain function, informed by the experiences of patients with brain diseases and those undergoing new brain-based therapies.

He is Co-Chair of the UCSF Department of Neurology Diversity Committee, is a member of the UCSF Medical Center Ethics Committee, and co-directs the Ethics, Law and Society Curriculum of the Global Brain Health Institute. Nationally, he serves on the Neuroethics Working Group of the National Institutes of Health BRAIN (Brain Research through Advancing Innovative Neurotechnologies) Multi-Council Working Group and the American Academy of Neurology’s Ethics, Law and Humanities Committee.

His work is informed by his interdisciplinary training in clinical medicine, philosophy and cognitive neuroscience. He received his PhD degree in philosophy from New York University and his MD degree from UCSF. He completed an internship in internal medicine at Stanford University and a residency in neurology at UCSF. He then underwent postdoctoral research training in cognitive neuroscience and neuroimaging at UC Berkeley and clinical training in dementia at the UCSF Memory and Aging Center.

Publications: 

Commentary 1: Researcher Integrity and Contrasting Obligations in Interdisciplinary Research.

Journal of empirical research on human research ethics : JERHRE

Chiong W, Haeusermann T

Ethical Challenges of Risk, Informed Consent, and Posttrial Responsibilities in Human Research With Neural Devices: A Review.

JAMA neurology

Hendriks S, Grady C, Ramos KM, Chiong W, Fins JJ, Ford P, Goering S, Greely HT, Hutchison K, Kelly ML, Kim SYH, Klein E, Lisanby SH, Mayberg H, Maslen H, Miller FG, Rommelfanger K, Sheth SA, Wexler A

Effect of Collaborative Dementia Care via Telephone and Internet on Quality of Life, Caregiver Well-being, and Health Care Use: The Care Ecosystem Randomized Clinical Trial.

JAMA internal medicine

Possin KL, Merrilees JJ, Dulaney S, Bonasera SJ, Chiong W, Lee K, Hooper SM, Allen IE, Braley T, Bernstein A, Rosa TD, Harrison K, Begert-Hellings H, Kornak J, Kahn JG, Naasan G, Lanata S, Clark AM, Chodos A, Gearhart R, Ritchie C, Miller BL

Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics.

Frontiers in neuroscience

Ramirez-Zamora A, Giordano J, Boyden ES, Gradinaru V, Gunduz A, Starr PA, Sheth SA, McIntyre CC, Fox MD, Vitek J, Vedam-Mai V, Akbar U, Almeida L, Bronte-Stewart HM, Mayberg HS, Pouratian N, Gittis AH, Singer AC, Creed MC, Lazaro-Munoz G, Richardson M, Rossi MA, Cendejas-Zaragoza L, D'Haese PF, Chiong W, Gilron R, Chizeck H, Ko A, Baker KB, Wagenaar J, Harel N, Deeb W, Foote KD, Okun MS

Variations in Costs of a Collaborative Care Model for Dementia.

Journal of the American Geriatrics Society

Rosa TD, Possin KL, Bernstein A, Merrilees J, Dulaney S, Matuoka J, Lee KP, Chiong W, Bonasera SJ, Harrison KL, Kahn JG

Association Between Caregiver Depression and Emergency Department Use Among Patients With Dementia.

JAMA neurology

Guterman EL, Allen IE, Josephson SA, Merrilees JJ, Dulaney S, Chiong W, Lee K, Bonasera SJ, Miller BL, Possin KL

The costs of dementia subtypes to California Medicare fee-for-service, 2015.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Chen Y, Wilson L, Kornak J, Dudley RA, Merrilees J, Bonasera SJ, Byrne CM, Lee K, Chiong W, Miller BL, Possin KL

Individual differences in level of wisdom are associated with brain activation during a moral decision-making task.

Brain and behavior

Thomas ML, Martin AS, Eyler L, Lee EE, Macagno E, Devereaux M, Chiong W, Jeste DV

Dopamine receptor D4 (DRD4) polymorphisms with reduced functional potency intensify atrophy in syndrome-specific sites of frontotemporal dementia.

NeuroImage. Clinical

Butler PM, Chiong W, Perry DC, Miller ZA, Gennatas ED, Brown JA, Pasquini L, Karydas A, Dokuru D, Coppola G, Sturm VE, Boxer AL, Gorno-Tempini ML, Rosen HJ, Kramer JH, Miller BL, Seeley WW

The NIH BRAIN Initiative: Integrating Neuroethics and Neuroscience.

Neuron

Ramos KM, Grady C, Greely HT, Chiong W, Eberwine J, Farahany NA, Johnson LSM, Hyman BT, Hyman SE, Rommelfanger KS, Serrano EE, Churchill JD, Gordon JA, Koroshetz WJ

Neurodegenerative disorders of the human frontal lobes.

Handbook of clinical neurology

Butler PM, Chiong W

The Role of Care Navigators Working with People with Dementia and Their Caregivers.

Journal of Alzheimer's disease : JAD

Bernstein A, Harrison KL, Dulaney S, Merrilees J, Bowhay A, Heunis J, Choi J, Feuer JE, Clark AM, Chiong W, Lee K, Braley TL, Bonasera SJ, Ritchie C, Dohan D, Miller BL, Possin KL

Neuroethics Guiding Principles for the NIH BRAIN Initiative.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Greely HT, Grady C, Ramos KM, Chiong W, Eberwine J, Farahany NA, Johnson LSM, Hyman BT, Hyman SE, Rommelfanger KS, Serrano EE

The Care Ecosystem: Promoting self-efficacy among dementia family caregivers.

Dementia (London, England)

Merrilees JJ, Bernstein A, Dulaney S, Heunis J, Walker R, Rah E, Choi J, Gawlas K, Carroll S, Ong P, Feuer J, Braley T, Clark AM, Lee K, Chiong W, Bonasera SJ, Miller BL, Possin KL

Head Positioning in Acute Stroke.

The New England journal of medicine

Feldman WB, Chiong W, Kim SYH

Development of an adaptive, personalized, and scalable dementia care program: Early findings from the Care Ecosystem.

PLoS medicine

Possin KL, Merrilees J, Bonasera SJ, Bernstein A, Chiong W, Lee K, Wilson L, Hooper SM, Dulaney S, Braley T, Laohavanich S, Feuer JE, Clark AM, Schaffer MW, Schenk AK, Heunis J, Ong P, Cook KM, Bowhay AD, Gearhart R, Chodos A, Naasan G, Bindman AB, Dohan D, Ritchie C, Miller BL

Distinct Subtypes of Behavioral Variant Frontotemporal Dementia Based on Patterns of Network Degeneration.

JAMA neurology

Ranasinghe KG, Rankin KP, Pressman PS, Perry DC, Lobach IV, Seeley WW, Coppola G, Karydas AM, Grinberg LT, Shany-Ur T, Lee SE, Rabinovici GD, Rosen HJ, Gorno-Tempini ML, Boxer AL, Miller ZA, Chiong W, DeMay M, Kramer JH, Possin KL, Sturm VE, Bettcher BM, Neylan M, Zackey DD, Nguyen LA, Ketelle R, Block N, Wu TQ, Dallich A, Russek N, Caplan A, Geschwind DH, Vossel KA, Miller BL

Effect of waivers of consent on recruitment in acute stroke trials: A systematic review.

Neurology

Feldman WB, Kim AS, Josephson SA, Lowenstein DH, Chiong W

Neuroeconomic dissociation of semantic dementia and behavioural variant frontotemporal dementia.

Brain : a journal of neurology

Chiong W, Wood KA, Beagle AJ, Hsu M, Kayser AS, Miller BL, Kramer JH

Inability to consent does not diminish the desirability of stroke thrombolysis.

Annals of neurology

Chiong W, Kim AS, Huang IA, Farahany NA, Josephson SA

Testing the presumption of consent to emergency treatment for acute ischemic stroke.

JAMA

Chiong W, Kim AS, Huang IA, Farahany NA, Josephson SA

The salience network causally influences default mode network activity during moral reasoning.

Brain : a journal of neurology

Chiong W, Wilson SM, D'Esposito M, Kayser AS, Grossman SN, Poorzand P, Seeley WW, Miller BL, Rankin KP

Financial errors in dementia: testing a neuroeconomic conceptual framework.

Neurocase

Chiong W, Hsu M, Wudka D, Miller BL, Rosen HJ

Equipoise and the dilemma of randomized clinical trials.

The New England journal of medicine

Chiong W

The real problem with equipoise.

The American journal of bioethics : AJOB

Chiong W

Brain death without definitions.

The Hastings Center report

Chiong W

Industry-to-physician marketing and the cost of prescription drugs.

The American journal of bioethics : AJOB

Chiong W

PHOG, a candidate gene for involvement in the short stature of Turner syndrome.

Human molecular genetics

Ellison JW, Wardak Z, Young MF, Gehron Robey P, Laig-Webster M, Chiong W