bioRxiv

Non-Coding and Loss-of-Function Coding Variants in TET2 are Associated with Multiple Neurodegenerative Diseases.

bioRxiv

J. Nicholas Cochran, Ethan G. Geier, Luke W. Bonham, J. Scott Newberry, Michelle D. Amaral, Michelle L. Thompson, Brittany N. Lasseigne, Anna M. Karydas, Erik D. Roberson, Gregory M. Cooper, Gil D. Rabinovici, Bruce L. Miller, Richard M. Myers, Jennifer S. Yokoyama

Genome sequencing for early-onset dementia: high diagnostic yield and frequent observation of multiple contributory alleles.

bioRxiv

J. Nicholas Cochran, Emily C. McKinley, Meagan Cochran, Michelle D. Amaral, Bryan A. Moyers, Brittany N. Lasseigne, David E. Gray, James M.J. Lawlor, Jeremy W. Prokop, Ethan G. Geier, James M. Holt, Michelle L. Thompson, J. Scott Newberry, Jennifer S. Yokoyama, Elizabeth A. Worthey, David S. Geldmacher, Marissa Natelson Love, Gregory M. Cooper, Richard M. Myers, Erik D. Roberson

State and trait characteristics of anterior insula time-varying functional connectivity.

bioRxiv

Lorenzo Pasquini, Gianina Toller, Adam Staffaroni, Jesse A. Brown, Jersey Deng, Alex Lee, Katarzyna Kurcyus, Suzanne M Shdo, Isabel Allen, Virginia E Sturm, Yann Cobigo, Valentina Borghesani, Giovanni Battistella, Maria Luisa Gorno-Tempini, Katherine P. Rankin, Joel Kramer, Howard H. Rosen, Bruce L. Miller, William W. Seeley

Salience network atrophy links neuron type-specific degeneration to loss of empathy in frontotemporal dementia.

bioRxiv

Lorenzo Pasquini, Alissa L. Nana, Gianina Toller, Jesse Brown, Jersey Deng, Adam Staffaroni, Eun-Joo Kim, Ji-Hye L. Hwang, Libo Li, Youngsoon Park, Stephanie E. Gaus, Isabel Allen, Virginia E. Sturm, Salvatore Spina, Lea T. Grinberg, Katherine P. Rankin, Joel Kramer, Howard H. Rosen, Bruce L. Miller, William W. Seeley

Endothelial-derived exosomes demonstrate a link between endothelial innate inflammation and brain dysfunction and injury in aging.

bioRxiv

Fanny M. Elahi, Danielle J. Harvey, Marie Altendahl, Kaitlin B. Casaletto, Nicole Fernandes, Adam M. Staffaroni, Pauline Maillard, Jason D. Hinman, Bruce L. Miller, Charles DeCarli, Joel H. Kramer, Edward J. Goetzl

Endothelial-derived exosomes demonstrate a link between endothelial innate inflammation and brain dysfunction and injury in aging.

bioRxiv

Fanny M. Elahi,Danielle J. Harvey,Marie Altendahl,Kaitlin B. Casaletto,Nicole Fernandes,Adam M. Staffaroni,Pauline Maillard,Jason D. Hinman,Bruce L. Miller,Charles DeCarli,Joel H. Kramer,Edward J. Goetzl

Human subsystems of medial temporal lobes extend locally to amygdala nuclei and globally to an allostatic-interoceptive system.

bioRxiv

Adriana L. Ruiz-Rizzo, Florian Beissner, Kathrin Finke, Hermann J. Müller, Claus Zimmer, Lorenzo Pasquini, Christian Sorg

Partitioning the genetic architecture of amyotrophic lateral sclerosis.

bioRxiv

Iris J Broce, Chun C Fan, Nicholas T Olney, Catherine Lomen-Hoerth, Steve Finkbeiner, Nazem Atassi, Merit E Cudkowicz, Sabrina Paganoni, Jennifer S Yokoyama, Aimee Kao, William P Dillon, Christine M Glastonbury, Christopher P Hess, Wouter van Rheenen, Jan H Veldink, Ammar Al-Chalabi, Ole A Andreassen, Anders M Dale, William W Seeley, Leo P Sugrue, Aaron Ofori-Kuragu, Celeste M Karch, Bruce L Miller, Rahul S Desikan

C. elegans granulins promote an age-associated decline in protein homeostasis via lysosomal protease inhibition.

bioRxiv

Victoria J Butler, Wilian Augusto Cortopassi, Andrea R Argouarch, Olivia M Pierce, Mihir Vohra, Juan A Oses-Prieto, Fuying Gao, Benjamin Caballero, Shreya Chand, William W Seeley, Bruce L Miller, Giovanni Coppola, Alma L Burlingame, Kaveh Ashrafi, Ana Maria Cuervo, Matt Jacobson, Aimee W Kao

Chronotopic Maps in Human Medial Premotor Cortex.

bioRxiv

Foteini Protopapa, Masamichi Hayashi, Shrikanth Kulashekhar, Wietske van der Zwaag, Giovanni Battistella, Micah M Murray, Ryota Kanai, Domenica Bueti

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