Sevinc Jakab, PhD

Sevinc Jakab, PhD
Postdoctoral Fellow in Neuropathology
Fields of Interest

Sevinç joined the Seeley Lab as a postdoctoral scholar in October 2023. She earned a BSc degree in molecular biology and genetics from Boğaziçi University in Turkey. She then moved to Germany, where she completed an MSc degree in developmental and stem cell biology at Heidelberg University. For her master’s thesis, she focused on establishing culture conditions for circulating tumor cells from breast cancer patients in the lab of Andreas Trumpp at the German Cancer Research Center.

Driven by an interest in neuroscience, Sevinç pursued a PhD degree in the laboratory of Joachim Wittbrodt at Heidelberg University, where she investigated the role of glycosylation during retinal development. Her doctoral thesis demonstrated that hypomorphic mutations in the N-glycosylation machinery lead to selective cell death in the vertebrate retina.

Currently, her research focuses on elucidating the mechanisms of TDP-43 pathology in the brains of patients with FTD and ALS who carry the C9orf72 hexanucleotide repeat expansion.