Sevinc Jakab, PhD

Sevinç joined the Seeley Lab as a postdoctoral scholar in October 2023. She completed her BSc degree in Molecular Biology and Genetics at Boğaziçi University in Turkey. She then moved to Germany, where she earned her MSc degree in Developmental and Stem Cell Biology from Heidelberg University. Her Master's thesis focused on establishing culture conditions for circulating tumor cells from breast cancer patients in the lab of Andreas Trumpp at the German Cancer Research Center. Driven by an interest in neuroscience, Sevinç pursued a PhD degree in the laboratory of Joachim Wittbrodt at Heidelberg University, concentrating on the role of glycosylation during retinal development. Her PhD thesis demonstrated that hypomorphic mutations in the N-glycosylation machinery lead to selective cell death in the vertebrate retina. Currently, her research aims to elucidate the mechanisms of TDP-43 pathology in the brains of FTD and ALS patients carrying the C9orf72 hexanucleotide repeat expansion.