Peter Ljubenkov, MD

Assistant Professor
+1 415 476-6880
Fields of Interest: 
Clinical Trials
Professional Education

Dr. Peter A. Ljubenkov is a behavioral neurologist at the UCSF Memory and Aging Center and specializes in caring for patients experiencing memory, language and behavioral changes due to neurological conditions, such as Alzheimer’s disease, Lewy body dementia, and other causes of dementia. He has special expertise in diagnosing and treating frontotemporal dementia (a group of neurodegenerative diseases that affect the frontal and temporal lobes) and related conditions, including progressive supranuclear palsy and corticobasal degeneration. Ljubenkov also serves as the associate fellowship director of the UCSF Memory and Aging Center's Behavioral Neurology Training Program Fellowship (BNTP), a program that trains doctors for careers in research and clinical care involving patients with dementia. In research, Ljubenkov is active in clinical therapeutic trials, studies enrolling human participants to explore new potential treatments for patients with dementia. His current research focuses on biomarkers of frontotemporal dementia pathogenesis and progression, with a particular emphasis on measures of immune system dysregulation.

Ljubenkov earned his medical degree at the Lewis Katz School of Medicine at Temple University. He completed a residency in neurology at the University of California, San Diego, followed by a fellowship in behavioral neurology at UCSF. Dr. Ljubenkov has been a member of the Boxer lab since 2015 and was the 2017–2018 Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL) research fellow.

Publications: 

[18F]PI-2620 Binding Patterns in Patients with Suspected Alzheimer Disease and Frontotemporal Lobar Degeneration.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Blazhenets G, Soleimani-Meigooni DN, Thomas W, Mundada N, Brendel M, Vento S, VandeVrede L, Heuer HW, Ljubenkov P, Rojas JC, Chen MK, Amuiri AN, Miller Z, Gorno-Tempini ML, Miller BL, Rosen HJ, Litvan I, Grossman M, Boeve B, Pantelyat A, Tartaglia MC, Irwin DJ, Dickerson BC, Baker SL, Boxer AL, Rabinovici GD, La Joie R

Co-pathology may impact outcomes of amyloid-targeting treatments: clinicopathological results from two patients treated with aducanumab.

Acta neuropathologica

VandeVrede L, La Joie R, Horiki S, Mundada NS, Koestler M, Hwang JH, Ljubenkov PA, Rojas JC, Rabinovici GD, Boxer AL, Seeley WW

Silencing tau to treat early Alzheimer's disease.

Nature medicine

Ljubenkov PA, Rabinovici GD

Evaluation of Plasma Phosphorylated Tau217 for Differentiation Between Alzheimer Disease and Frontotemporal Lobar Degeneration Subtypes Among Patients With Corticobasal Syndrome.

JAMA neurology

VandeVrede L, La Joie R, Thijssen EH, Asken BM, Vento SA, Tsuei T, Baker SL, Cobigo Y, Fonseca C, Heuer HW, Kramer JH, Ljubenkov PA, Rabinovici GD, Rojas JC, Rosen HJ, Staffaroni AM, Boeve BF, Dickerson BC, Grossman M, Huey ED, Irwin DJ, Litvan I, Pantelyat AY, Tartaglia MC, Dage JL, Boxer AL

Plasma inflammation for predicting phenotypic conversion and clinical progression of autosomal dominant frontotemporal lobar degeneration.

Journal of neurology, neurosurgery, and psychiatry

Asken BM, Ljubenkov PA, Staffaroni AM, Casaletto KB, Vandevrede L, Cobigo Y, Rojas-Rodriguez JC, Rankin KP, Kornak J, Heuer H, Shigenaga J, Appleby BS, Bozoki AC, Domoto-Reilly K, Ghoshal N, Huey E, Litvan I, Masdeu JC, Mendez MF, Pascual B, Pressman P, Tartaglia MC, Kremers W, Forsberg LK, Boeve BF, Boxer AL, Rosen HJ, Kramer JH, ALLFTD Consortium Investigators

Autopsy Results from the ENGAGE Trial of Aducanumab: Lessons from Co-pathology.

Alzheimer's & Dementia

Sheena Horiki, Lawren VandeVrede, Renaud La Joie, Peter A. Ljubenkov, Mary Koestler, Julio C. Rojas, Gil D. Rabinovici, Adam L. Boxer, William W. Seeley

Introduction to Veri-T: A Phase 1 Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of Verdiperstat in Patients with svPPA Due to FTLD-TDP.

Alzheimer's & Dementia

Peter A. Ljubenkov, Adam M. Staffaroni, Julio C. Rojas, Lawren VandeVrede, Mary Koestler, Tayler A Sulse, Julia Moreton, Sheena Horiki, Hilary W. Heuer, Ian Grant, David J. Irwin, Bradley F. Boeve, Howard J. Rosen, David S. Knopman, Robert Bowser, Murray Grossman, Irfan Qureshi, Adam L. Boxer

The Neurofilament Surveillance Project (NSP): A biomarker study to sample blood quarterly in familial frontotemporal lobar degeneration.

Alzheimer's & Dementia

Rachel Acuna-Narvaez, Hilary W. Heuer, Leah K. Forsberg, Anne Alward, Danielle Graham, Ann Fishman, Kevin M Nelson, Tyler Kolander, Howard M Fillit, Wendy R Galpern, Serena Hung, Chris Mason, Laurence Mignon, Yan G Ni, Arthur Simen, Ina Tesseur, Richard Tsai, Felix L Yeh, Carly T. Mester, Peter A. Ljubenkov, Howard J. Rosen, Bradley F. Boeve, Adam L. Boxer, Rodney Pearlman, Laura L Mitic, NSP Site Investigators

[18F]PI-2620 PET in four-repeat tauopathies: a preliminary study.

Alzheimer's & Dementia

David N. Soleimani-Meigooni, Wesley P. Thomas, Matthias Brendel, Stephanie Vento, Hilary W. Heuer, Peter A. Ljubenkov, Julio C. Rojas, Miranda Chen, Leonardo Iaccarino, Renaud La Joie, Nidhi S. Mundada, Bradley F. Boeve, Murray Grossman, Bradford C. Dickerson, David J. Irwin, Irene Litvan, Alex Pantelyat, Carmela Tartaglia, Gil D. Rabinovici, Suzanne L. Baker, Adam L. Boxer

Temporal order of clinical and biomarker changes in familial frontotemporal dementia.

Nature medicine

Staffaroni AM, Quintana M, Wendelberger B, Heuer HW, Russell LL, Cobigo Y, Wolf A, Goh SM, Petrucelli L, Gendron TF, Heller C, Clark AL, Taylor JC, Wise A, Ong E, Forsberg L, Brushaber D, Rojas JC, VandeVrede L, Ljubenkov P, Kramer J, Casaletto KB, Appleby B, Bordelon Y, Botha H, Dickerson BC, Domoto-Reilly K, Fields JA, Foroud T, Gavrilova R, Geschwind D, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grossman M, Hall MGH, Hsiung GY, Huey ED, Irwin D, Jones DT, Kantarci K, Kaufer D, Knopman D, Kremers W, Lago AL, Lapid MI, Litvan I, Lucente D, Mackenzie IR, Mendez MF, Mester C, Miller BL, Onyike CU, Rademakers R, Ramanan VK, Ramos EM, Rao M, Rascovsky K, Rankin KP, Roberson ED, Savica R, Tartaglia MC, Weintraub S, Wong B, Cash DM, Bouzigues A, Swift IJ, Peakman G, Bocchetta M, Todd EG, Convery RS, Rowe JB, Borroni B, Galimberti D, Tiraboschi P, Masellis M, Finger E, van Swieten JC, Seelaar H, Jiskoot LC, Sorbi S, Butler CR, Graff C, Gerhard A, Langheinrich T, Laforce R, Sanchez-Valle R, de Mendonça A, Moreno F, Synofzik M, Vandenberghe R, Ducharme S, Le Ber I, Levin J, Danek A, Otto M, Pasquier F, Santana I, Kornak J, Boeve BF, Rosen HJ, Rohrer JD, Boxer AL, Frontotemporal Dementia Prevention Initiative (FPI) Investigators

Case Report: Novel CSF1R Variant in a Patient With Behavioral Variant Frontotemporal Dementia Syndrome With Prodromal Repetitive Scratching Behavior.

Frontiers in neurology

Friedberg A, Ramos EM, Yang Z, Bonham LW, Yokoyama JS, Ljubenkov PA, Younes K, Geschwind DH, Miller BL

Sensitivity of the Social Behavior Observer Checklist to Early Symptoms of Patients With Frontotemporal Dementia.

Neurology

Toller G, Cobigo Y, Ljubenkov PA, Appleby BS, Dickerson BC, Domoto-Reilly K, Fong JC, Forsberg LK, Gavrilova RH, Ghoshal N, Heuer HW, Knopman DS, Kornak J, Lapid MI, Litvan I, Lucente DE, Mckenzie IR, McGinnis SM, Miller BL, Pedraza O, Rojas JC, Staffaroni AM, Wong B, Wszolek ZK, Boeve BF, Boxer AL, Rosen HJ, Rankin KP, ALLFTD research consortium

Cerebrospinal Fluid Biomarkers in Autopsy-Confirmed Alzheimer Disease and Frontotemporal Lobar Degeneration.

Neurology

Mattsson-Carlgren N, Grinberg LT, Boxer A, Ossenkoppele R, Jonsson M, Seeley W, Ehrenberg A, Spina S, Janelidze S, Rojas-Martinex J, Rosen H, La Joie R, Lesman-Segev O, Iaccarino L, Kollmorgen G, Ljubenkov P, Eichenlaub U, Gorno-Tempini ML, Miller B, Hansson O, Rabinovici GD

Clinical value of CSF tau, p-tau181, neurogranin and neurofilaments in familial frontotemporal lobar degeneration.

Alzheimer's & Dementia

Julio C. Rojas, Hilary W. Heuer, Weiping Chen, Julie Czerkowicz, Danielle Graham, Leah K. Forsberg, Danielle Brushaber, Brian Appleby, Eliana Marisa Ramos, Giovanni Coppolla, Yvette M. Bordelon, Hugo Botha, Brad C. Dickerson, Dennis W. Dickson, Kimiko Domoto-Reilly, Anne M. Fagan, Julie A. Fields, Jamie C. Fong, Tatiana M. Foroud, Doug R. Galasko, Ralitza H. Gavrilova, Daniel H. Geschwind, Nupur Ghoshal, Jill Goldman, Neill R. Graff-Radford, Jonathan Graff-Radford, Ian Grant, Murray Grossman, Ging-Yuek Robin Hsiung, Eric J. Huang, Edward D. Huey, David J. Irwin, David T. Jones, Kejal Kantarci, David S. Knopman, John Kornak, Walter K. Kremers, Maria I. Lapid, Gabriel C. Leger, Irene Litvan, Peter A. Ljubenkov, Diane E. Lucente, Ian R Mackenzie, Joseph C. Masdeu, Corey T. McMillan, Mario F. Mendez, Bruce L. Miller, Toji Miyagawa, Chiadi U. Onyike, Belen Pascual, Otto Pedraza, Leonard Petrucelli, Rosa Rademakers, Katherine P. Rankin, Katya Rascovsky, Jessica E. Rexach, Aaron Ritter, Erik D. Roberson, Rodolfo Savica, William W. Seeley, Adam M. Staffaroni, Maria Carmela Tartaglia, Arthur W. Toga, Sandra Weintraub, Bonnie Wong, Zbigniew Wszolek, Lawren Vandevrede, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer

Demographic and psychosocial factors associated with the decision to learn mutation status in familial frontotemporal dementia and the impact of disclosure on mood.

Alzheimer's & Dementia

Lynn P. Bajorek, Rachel Kiekhofer, Matthew Hall, Joanne Taylor, Diane E Lucente, Danielle Brushaber, Brian Appleby, Giovanni Coppolla, Yvette M Bordelon, Hugo Botha, Brad C Dickerson, Dennis W Dickson, Kimiko Domoto-Reilly, Anne M Fagan, Julie A Fields, Jamie C Fong, Tatiana M Foroud, Leah K Forsberg, Doug R Galasko, Ralitza H Gavrilova, Daniel H Geschwind, Nupur Ghoshal, Jill Goldman, Neill R Graff-Radford, Jonathan Graff-Radford, Ian Grant, Murray Grossman, Hilary W Heuer, Ging-Yuek Robin Hsiung, Eric J Huang, Edward D Huey, David J Irwin, David T Jones, Kejal Kantarci, John Kornak, Walter K Kremers, Maria I Lapid, Gabriel C Leger, Irene Litvan, Peter A Ljubenkov, Ian R Mackenzie, Joseph C Masdeu, Corey McMillan, Mario Mendez, Bruce L Miller, Toji Miyagawa, Chiadi U Onyike, Belen Pascual, Otto Pedraza, Leonard Petrucelli, Rosa Rademakers, Eliana Marisa Ramos, Katherine P Rankin, Katya Rascovsky, Jessica E Rexach, Aaron Ritter, Erik D. Roberson, Rodolfo Savica, Julio C Rojas, William W Seeley, Maria Carmela Tartaglia, Arthur W Toga, Sandra Weintraub, Bonnie Wong, Zbigniew Wszolek, Lawren Vandevrede, Bradley F Boeve, Adam L Boxer, Howard J Rosen, Adam M Staffaroni, ALLFTD Consortium

Diagnostic value of plasma P-tau217 in frontotemporal dementia spectrum disorders.

Alzheimer's & Dementia

Julio C. Rojas, Lawren Vandevrede, Hilary W. Heuer, Gianina Toller, Elisabeth H. Thijssen, Nicholas Proctor, Leah K. Forsberg, Danielle Brushaber, Eliana Marisa Ramos, Giovanni Coppola, Brian Appleby, Yvette M. Bordelon, Hugo Botha, Brad C. Dickerson, Dennis W. Dickson, Kimiko Domoto-Reilly, Anne M. Fagan, Julie A. Fields, Jamie C. Fong, Tatiana M. Foroud, Doug R. Galasko, Ralitza H. Gavrilova, Daniel H. Geschwind, Nupur Ghoshal, Jill Goldman, Neill R. Graff-Radford, Jonathan Graff-Radford, Ian Grant, Murray Grossman, Ging-Yuek Robin Hsiung, Eric J. Huang, Edward D. Huey, David J. Irwin, David T. Jones, Kejal Kantarci, David S. Knopman, John Kornak, Walter K. Kremers, Maria I. Lapid, Gabriel C. Leger, Irene Litvan, Peter A. Ljubenkov, Diane E. Lucente, Ian R. Mackenzie, Joseph C. Masdeu, Corey T. McMillan, Mario Mendez, Bruce L. Miller, Toji Miyagawa, Chiadi U. Onyike, Belen Pascual, Otto Pedraza, Leonard Petrucelli, Rosa Rademakers, Katherine P. Rankin, Katya Rascovsky, Jessica E. Rexach, Aaron Ritter, Erik D. Roberson, Rodolfo Savica, William W. Seeley, Adam M. Staffaroni, Maria Carmela Trataglia, Arthur W. Toga, Sandra Weintraub, Bonnie Wong, Zbigniew Wszolek, Jeffrey L. Dage, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer

Gearing up for the future: Exploring facilitators and barriers to inform clinical trial design in frontotemporal lobar degeneration.

Alzheimer's & Dementia

Yasmin B Banga, Yujung Lai, Priscilla Kim, Bradley F Boeve, Adam L Boxer, Howard J Rosen, Leah K Forsberg, Hilary W Heuer, Danielle Brushaber, Brian Appleby, Joanna M Biernacka, Yvette M Bordelon, Hugo Botha, Andrea C Bozoki, Patrick Brannelly, Brad C Dickerson, Susan Dickinson, Dennis W Dickson, Kimiko Domoto-Reilly, Kelley Faber, Anne M Fagan, Julie A Fields, Ann Fishman, Tatiana M Foroud, Doug R Galasko, Ralitza H Gavrilova, Tania F Gendron, Daniel H Geschwind, Nupur Ghoshal, Jill Goldman, Jonathan Graff-Radford, Neill R Graff-Radford, Ian Grant, Murray Grossman, Ging-Yuek Robin Hsiung, Eric J Huang, Edward D Huey, David J Irwin, David T Jones, Kejal Kantarci, Anna M Karydas, Daniel Kaufer, David S Knopman, Joel H Kramer, Walter K Kremers, John Kornak, Walter A Kukull, Emma Lagone, Gabriel C Leger, Irene Litvan, Peter A Ljubenkov, Diane E Lucente, Ian R Mackenzie, Masood Manoochehri, Joseph C Masdeu, Scott McGinnis, Mario F Mendez, Bruce L Miller, Toji Miyagawa, Kevin M Nelson, Chiadi U Onyike, Alex Pantelyat, Belen Pascual, Rodney Pearlman, Leonard Petrucelli, Cyril P Pottier, Rosa Rademakers, Eliana Marisa Ramos, Katherine P Rankin, Katya Rascovsky, Jessica E Rexach, Aaron Ritter, Erik D Roberson, Julio C Rojas, Marwan N Sabbagh, David P Salmon, Rodolfo Savica, William W Seeley, Adam M Staffaroni, Jeremy A Syrjanen, Maria Carmela Tartaglia, Nadine Tatton, Jack C Taylor, Arthur W Toga, Sandra Weintraub, Diana Wheaton, Benjamin Wong, Zbigniew Wszolek, ALLFTD Consortium

Effect of the Histone Deacetylase Inhibitor FRM-0334 on Progranulin Levels in Patients With Progranulin Gene Haploinsufficiency: A Randomized Clinical Trial.

JAMA network open

Ljubenkov PA, Edwards L, Iaccarino L, La Joie R, Rojas JC, Koestler M, Harris B, Boeve BF, Borroni B, van Swieten JC, Grossman M, Pasquier F, Frisoni GB, Mummery CJ, Vandenberghe R, Le Ber I, Hannequin D, McGinnis SM, Auriacombe S, Onofrj M, Goodman IJ, Riordan HJ, Wisniewski G, Hesterman J, Marek K, Haynes BA, Patzke H, Koenig G, Hilt D, Moebius H, Boxer AL

Best Practices in the Clinical Management of Progressive Supranuclear Palsy and Corticobasal Syndrome: A Consensus Statement of the CurePSP Centers of Care.

Frontiers in neurology

Bluett B, Pantelyat AY, Litvan I, Ali F, Apetauerova D, Bega D, Bloom L, Bower J, Boxer AL, Dale ML, Dhall R, Duquette A, Fernandez HH, Fleisher JE, Grossman M, Howell M, Kerwin DR, Leegwater-Kim J, Lepage C, Ljubenkov PA, Mancini M, McFarland NR, Moretti P, Myrick E, Patel P, Plummer LS, Rodriguez-Porcel F, Rojas J, Sidiropoulos C, Sklerov M, Sokol LL, Tuite PJ, VandeVrede L, Wilhelm J, Wills AA, Xie T, Golbe LI

Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration.

Neurology

Rojas JC, Wang P, Staffaroni AM, Heller C, Cobigo Y, Wolf A, Goh SM, Ljubenkov PA, Heuer HW, Fong JC, Taylor JB, Veras E, Song L, Jeromin A, Hanlon D, Yu L, Khinikar A, Sivasankaran R, Kieloch A, Valentin MA, Karydas AM, Mitic LL, Pearlman R, Kornak J, Kramer JH, Miller BL, Kantarci K, Knopman DS, Graff-Radford N, Petrucelli L, Rademakers R, Irwin DJ, Grossman M, Ramos EM, Coppola G, Mendez MF, Bordelon Y, Dickerson BC, Ghoshal N, Huey ED, Mackenzie IR, Appleby BS, Domoto-Reilly K, Hsiung GR, Toga AW, Weintraub S, Kaufer DI, Kerwin D, Litvan I, Onyike CU, Pantelyat A, Roberson ED, Tartaglia MC, Foroud T, Chen W, Czerkowicz J, Graham DL, van Swieten JC, Borroni B, Sanchez-Valle R, Moreno F, Laforce R, Graff C, Synofzik M, Galimberti D, Rowe JB, Masellis M, Finger E, Vandenberghe R, de Mendonça A, Tagliavini F, Santana I, Ducharme S, Butler CR, Gerhard A, Levin J, Danek A, Otto M, Sorbi S, Cash DM, Convery RS, Bocchetta M, Foiani M, Caroline V G, Peakman G, Russell L, Swift I, Todd E, Rohrer JD, Boeve BF, Rosen HJ, Boxer AL

FTLD Treatment: Current Practice and Future Possibilities.

Advances in experimental medicine and biology

Ljubenkov PA, Boxer AL

Lipid metabolism dysfunction in progranulin mutation carriers: Unbiased metabolomics reveals strong relationship to clinical status in FTLD.

Alzheimer's & Dementia

Lawren Vandevrede, Julio C. Rojas, Ping Wang, Hilary W. Heuer, Anna M. Karydas, Peter A. Ljubenkov, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer, ARTFL and LEFFTDS Consortia Investigators

Neuropsychiatric abnormalities in familial frontotemporal dementia: Findings from the LEFFTDS Cohort.

Alzheimer's & Dementia

Leah K. Forsberg, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer, Jeremy Syrjanen, Danielle Brushaber, Giovanni Coppolla, Brad C. Dickerson, Julie A. Fields, Jamie Fong, Ralitza H. Gavrilova, Nupur Ghoshal, Jill Goldman, Jonathan Graff-Radford, Neill R. Graff-Radford, Murray Grossman, Hilary W. Heuer, Ging-Yuek Robin Hsiung, Edward Huey, David J. Irwin, David T. Jones, Kejal Kantarci, Anna M. Karydas, David S. Knopman, John Kornak, Joel H. Kramer, Walter K. Kremers, Walter A. Kukull, Peter A. Ljubenkov, Ian R. Mackenzie, Scott McGinnis, Bruce L. Miller, Rosa Rademakers, Eliana Marisa Ramos, Katherine Rankin, Katya Rascovsky, Virginia Sturm, Adam M. Staffaroni, Joanne Taylor, Bonnie Wong, Zbigniew Wszolek

Plasma biomarkers of inflammation reflect disease state in autosomal dominant forms of familial frontotemporal dementia.

Alzheimer's & Dementia

Peter A. Ljubenkov, Adam M. Staffaroni, Kaitlin B. Casaletto, Julio C. Rojas, Lawren Vandevrede, Hilary W. Heuer, Fanny M. Elahi, Danielle Brushaber, Tatiana M. Foroud, Leah K. Forsberg, Anna M. Karydas, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer, Joel H. Kramer, ARTFL and LEFFTDS Consortium Investigators

Plasma neurofilament light chain levels reflect caregiver burden and social cognition measures in familial frontotemporal lobar degeneration (FTLD).

Alzheimer's & Dementia

Hilary W. Heuer, Julio C. Rojas, Gianina Toller, Katherine Rankin, Danielle Brushaber, Brian Appleby, Yvette M. Bordelon, Brad C. Dickerson, Domoto-Reilly Kimiko, Kelley Faber, Tatiana M. Foroud, Leah K Forsberg, Nupur Ghoshal, Ian Grant, Neill R. Graff-Radford, Murray Grossman, Ging-Yuek Robin Hsiung, Edward D. Huey, Anna M. Karydas, Daniel Kaufer, Diana R. Kerwin, Emma Lagone, Irene Litvan, Peter A. Ljubenkov, Ian R. Mackenzie, Mario F. Mendez, Bruce L. Miller, Chiadi U. Onyike, Eliana Marisa Ramos, Katya Rascovsky, Erik D. Roberson, Carmela Tartaglia, Sandra Weintraub, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer, ARTFL/LEFFTDS Investigators

Studying the natural history of frontotemporal lobar degeneration (FTLD): The ARTFL LEFFTDS longitudinal FTLD (ALLFTD) protocol.

Alzheimer's & Dementia

Bradley F. Boeve, Adam L. Boxer, Howard J. Rosen, Leah K. Forsberg, Hilary W. Heuer, Danielle Brushaber, Brian Appleby, Joanna M. Biernacka, Yvette M. Bordelon, Hugo Botha, Patrick Brannelly, Brad C. Dickerson, Dennis W. Dickson, Domoto-Reilly Kimiko, Kelley Faber, Anne Fagan, Julie A. Fields, Ann Fishman, Tatiana M. Foroud, Doug R. Galasko, Ralitza H. Gavrilova, Tania F. Gendron, Daniel H. Geschwind, Nupur Ghoshal, Jill Goldman, Jonathan Graff-Radford, Neill R. Graff-Radford, Ian Grant, Murray Grossman, Ging-Yuek Robin Hsiung, Eric J. Huang, Edward Huey, David J. Irwin, David T. Jones, Kejal Kantarci, Anna M. Karydas, Daniel Kaufer, David S. Knopman, Joel H. Kramer, Walter K. Kremers, John Kornak, Walter A. Kukull, Emma Lagone, Gabriel C. Leger, Irene Litvan, Peter A. Ljubenkov, Diane E Lucente, Ian R Mackenzie, Masood Manoochehri, Joseph C. Masdeu, Scott McGinnis, Mario F. Mendez, Bruce L. Miller, Toji Miyagawa, Kevin M. Nelson, Chiadi U Onyike, Alex Pantelyat, Belen Pascual, Rodney Pearlman, Leonard Petrucelli, Rosa Rademakers, Eliana Marisa Ramos, Katherine Rankin, Katya Rascovsky, Jessica E. Rexach, Aaron Ritter, Erik D. Roberson, Julio C. Rojas, Marwan N. Sabbagh, David P. Salmon, Rodolfo Savica, William W. Seeley, Adam M. Staffaroni, Jeremy Syrjanen, Carmela Tartaglia, Nadine Tatton, Joanne Taylor, Arthur W. Toga, Sandra Weintraub, Diana Wheaton, Bonnie Wong, Zbigniew Wszolek

Symptomatic amyloid-related imaging abnormalities in an APOE e4/e4 patient treated with aducanumab.

Alzheimer's & dementia (Amsterdam, Netherlands)

VandeVrede L, Gibbs DM, Koestler M, La Joie R, Ljubenkov PA, Provost K, Soleimani-Meigooni D, Strom A, Tsoy E, Rabinovici GD, Boxer AL

Four-Repeat Tauopathies: Current Management and Future Treatments.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

VandeVrede L, Ljubenkov PA, Rojas JC, Welch AE, Boxer AL

Open-Label Phase 1 Futility Studies of Salsalate and Young Plasma in Progressive Supranuclear Palsy.

Movement disorders clinical practice

VandeVrede L, Dale ML, Fields S, Frank M, Hare E, Heuer HW, Keith K, Koestler M, Ljubenkov PA, McDermott D, Ohanesian N, Richards J, Rojas JC, Thijssen EH, Walsh C, Wang P, Wolf A, Quinn JF, Tsai R, Boxer AL

Association of Cognitive and Behavioral Features Between Adults With Tuberous Sclerosis and Frontotemporal Dementia.

JAMA neurology

Liu AJ, Staffaroni AM, Rojas-Martinez JC, Olney NT, Alquezar-Burillo C, Ljubenkov PA, La Joie R, Fong JC, Taylor J, Karydas A, Ramos EM, Coppola G, Boxer AL, Rabinovici GD, Miller BL, Kao AW

Reactions to Multiple Ascending Doses of the Microtubule Stabilizer TPI-287 in Patients With Alzheimer Disease, Progressive Supranuclear Palsy, and Corticobasal Syndrome: A Randomized Clinical Trial.

JAMA neurology

Tsai RM, Miller Z, Koestler M, Rojas JC, Ljubenkov PA, Rosen HJ, Rabinovici GD, Fagan AM, Cobigo Y, Brown JA, Jung JI, Hare E, Geldmacher DS, Natelson-Love M, McKinley EC, Luong PN, Chuu EL, Powers R, Mumford P, Wolf A, Wang P, Shamloo M, Miller BL, Roberson ED, Boxer AL

Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Olney NT, Ong E, Goh SM, Bajorek L, Dever R, Staffaroni AM, Cobigo Y, Bock M, Chiang K, Ljubenkov P, Kornak J, Heuer HW, Wang P, Rascovsky K, Wolf A, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dickerson BC, Dickinson S, Domoto-Reilly K, Faber K, Ferrall J, Fields J, Fishman A, Fong J, Foroud T, Forsberg LK, Gearhart DJ, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford NR, Grant I, Grossman M, Haley D, Hsiung G, Huey ED, Irwin DJ, Jones DT, Kantarci K, Karydas AM, Kaufer D, Kerwin D, Knopman DS, Kramer JH, Kraft R, Kremers W, Kukull W, Lapid MI, Litvan I, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley EC, Mendez MF, Miller BL, Onyike C, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wong B, Wszolek Z, Boxer AL, Boeve BF, Rosen HJ

Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Staffaroni AM, Cobigo Y, Goh SM, Kornak J, Bajorek L, Chiang K, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dever R, Dheel C, Dickerson BC, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fields JA, Fishman A, Fong J, Foroud T, Forsberg LK, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Heuer HW, Hsiung GY, Huey ED, Irwin DJ, Jones DT, Jones L, Kantarci K, Karydas A, Kaufer DI, Kerwin DR, Knopman DS, Kraft R, Kramer JH, Kremers WK, Kukull WA, Litvan I, Ljubenkov PA, Lucente D, Lungu C, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley E, Mendez MF, Miller BL, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wang P, Wong B, Wszolek Z, Boxer AL, Boeve BF, Rosen HJ

Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Staffaroni AM, Bajorek L, Casaletto KB, Cobigo Y, Goh SM, Wolf A, Heuer HW, Elahi FM, Ljubenkov PA, Dever R, Kornak J, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dheel C, Dickerson BC, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fields JA, Fishman A, Fong J, Foroud T, Forsberg LK, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Hsiung GY, Huey ED, Irwin DJ, Jones DT, Jones L, Kantarci K, Karydas A, Kaufer DI, Kerwin DR, Knopman DS, Kraft R, Kremers WK, Kukull WA, Litvan I, Lucente D, Lungu C, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley E, Mendez MF, Miller BL, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wang P, Wong B, Wszolek Z, Boxer AL, Boeve BF, Kramer JH, Rosen HJ

Comparison of sporadic and familial behavioral variant frontotemporal dementia (FTD) in a North American cohort.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Heuer HW, Wang P, Rascovsky K, Wolf A, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber DE, Caso C, Coppola G, Dickerson B, Dickinson S, Domoto-Reilly K, Faber K, Ferrall J, Fields J, Fishman A, Fong J, Foroud T, Forsberg LK, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Hsiung GY, Huey E, Irwin D, Jones D, Kantarci K, Karydas A, Kaufer D, Kerwin D, Knopman D, Kornak J, Kramer JH, Kraft R, Kremers WK, Kukull W, Litvan I, Ljubenkov P, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis S, McKinley E, Mendez MF, Miller BL, Onyike C, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Roberson ED, Rogalski E, Sengdy P, Shaw L, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski J, Weintraub S, Wong B, Wszolek Z, Boeve BF, Rosen HJ, Boxer AL

Genetic screening of a large series of North American sporadic and familial frontotemporal dementia cases.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Ramos EM, Dokuru DR, Van Berlo V, Wojta K, Wang Q, Huang AY, Deverasetty S, Qin Y, van Blitterswijk M, Jackson J, Appleby B, Bordelon Y, Brannelly P, Brushaber DE, Dickerson B, Dickinson S, Domoto-Reilly K, Faber K, Fields J, Fong J, Foroud T, Forsberg LK, Gavrilova R, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Heuer HW, Hsiung GR, Huey E, Irwin D, Kantarci K, Karydas A, Kaufer D, Kerwin D, Knopman D, Kornak J, Kramer JH, Kremers W, Kukull W, Litvan I, Ljubenkov P, Lungu C, Mackenzie I, Mendez MF, Miller BL, Onyike C, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Shaw L, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wong B, Wszolek Z, Rademakers R, Boeve BF, Rosen HJ, Boxer AL, Coppola G

Nonlinear Z-score modeling for improved detection of cognitive abnormality.

Alzheimer's & dementia (Amsterdam, Netherlands)

Kornak J, Fields J, Kremers W, Farmer S, Heuer HW, Forsberg L, Brushaber D, Rindels A, Dodge H, Weintraub S, Besser L, Appleby B, Bordelon Y, Bove J, Brannelly P, Caso C, Coppola G, Dever R, Dheel C, Dickerson B, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fishman A, Fong J, Foroud T, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant IM, Grossman M, Haley D, Hsiao J, Hsiung R, Huey ED, Irwin D, Jones D, Jones L, Kantarci K, Karydas A, Kaufer D, Kerwin D, Knopman D, Kraft R, Kramer J, Kukull W, Lapid M, Litvan I, Ljubenkov P, Lucente D, Lungu C, Mackenzie I, Maldonado M, Manoochehri M, McGinnis S, McKinley E, Mendez M, Miller B, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin K, Rascovsky K, Roberson ED, Rogalski-Miller E, Sengdy P, Shaw L, Staffaroni AM, Sutherland M, Syrjanen J, Tartaglia C, Tatton N, Taylor J, Toga A, Trojanowski J, Wang P, Wong B, Wszolek Z, Boeve B, Boxer A, Rosen H

Peripheral Innate Immune Activation Correlates With Disease Severity in GRN Haploinsufficiency.

Frontiers in neurology

Ljubenkov PA, Miller Z, Mumford P, Zhang J, Allen IE, Mitic L, Staffaroni A, Heuer H, Rojas JC, Cobigo Y, Karydas A, Pearlman R, Miller B, Kramer JH, McGrath MS, Rosen HJ, Boxer AL

FRONTOTEMPORAL LOBAR DEGENERATION RESEARCH IN NORTH AMERICA: PROGRESS IN THE ARTFL/LEFFTDS CONSORTIA.

Alzheimer's & Dementia

Hilary W. Heuer, Adam L. Boxer, Bradley F. Boeve, Howard J. Rosen, Leah K. Forsberg, Danielle Brushaber, Brian Appleby, Yvette M. Bordelon, Patrick Brannelly, Giovanni Coppola, Brad C. Dickerson, Susan Dickinson, Domoto-Reilly Kimiko, Kelley Faber, Julie A. Fields, Jamie Fong, Tatiana M. Foroud, Ralitza H. Gavrilova, Nupur Ghoshal, Jill Goldman, Jonathan Graff-Radford, Neil R. Graff-Radford, Ian Grant, Murray Grossman, John Hsiao, Ging-Yuek Robin Hsiung, Edward Huey, David Irwin, Kejal Kantarci, Anna M. Karydas, Daniel Kaufer, Diana R. Kerwin, David S. Knopman, Joel H. Kramer, Walter K. Kremers, Walter A. Kukull, Irene Litvan, Peter A. Ljubenkov, Diane E. Lucente, Codrin Lungu, Ian R. Mackenzie, Scott M. McGinnis, Mario F. Mendez, Bruce L. Miller, Chiadi U. Onyike, Alex Pantelyat, Rodney Pearlman, Leonard Petrucelli, Rosa Rademakers, Eliana Marisa Ramos, Katherine Rankin, Katya Rascovsky, Erik D. Roberson, Emily J. Rogalski, Leslie M. Shaw, Margaret Sutherland, Jeremy Syrjanen, Carmela Tartaglia, Nadine Tatton, Joanne Taylor, Arthur W. Toga, Sandra Weintraub, Bonnie Wong, Zbigniew Wszolek, ARTFL and LEFFTDS Consortia

THE MULTIDOMAIN IMPAIRMENT RATING (MIR) SCALE: INITIAL RELIABILITY DATA ON A MULTIDIMENSIONAL SCALE DESIGNED FOR FTLD SPECTRUM DISORDERS.

Alzheimer's & Dementia

Leah K. Forsberg, Bradley F. Boeve, Adam L. Boxer, Howard J. Rosen, John Kornak, Hilary W. Heuer, Julie A. Fields, Danielle Brushaber, Mary M. Machulda, Virginia Sturm, Adam M. Staffaroni, Peter A. Ljubenkov, Reilly Denver, Elise Ong, Brian Appleby, Yvette M. Bordelon, Patrick Brannelly, Giovanni Coppola, Brad C. Dickerson, Susan Dickinson, Domoto-Reilly Kimiko, Kelley Faber, Jamie Fong, Tatiana M. Foroud, Ralitza H. Gavrilova, Debra Gearhart, Nupur Ghoshal, Jill Goldman, Jonathan Graff-Radford, Neil R. Graff-Radford, Murray Grossman, Ging-Yuek Robin Hsiung, Edward D. Huey, David Irwin, David T. Jones, Kejal Kantarci, Anna M. Karydas, Daniel Kaufer, Diana R. Kerwin, David S. Knopman, Ruth A. Kraft, Joel H. Kramer, Walter K. Kremers, Walter A. Kukull, Irene Litvan, Diane E. Lucente, Codrin Lungu, Ian R. Mackenzie, Scott M. McGinnis, Mario F. Mendez, Bruce L. Miller, Chiadi U. Onyike, Alex Pantelyat, Rodney Pearlman, Leonard Petrucelli, Madeline Potter, Rosa Rademakers, Eliana Marisa Ramos, Katherine Rankin, Katya Rascovsky, Erik D. Roberson, Emily J. Rogalski, Leslie M. Shaw, Marg Sutherland, Jeremy Syrjanen, Carmela Tartaglia, Nadine Tatton, Joanne Taylor, Arthur W. Toga, John Q. Trojanowski, Sandra Weintraub, Bonnie Wong, Zbigniew Wszolek

Longitudinal multimodal imaging and clinical endpoints for frontotemporal dementia clinical trials.

Brain : a journal of neurology

Staffaroni AM, Ljubenkov PA, Kornak J, Cobigo Y, Datta S, Marx G, Walters SM, Chiang K, Olney N, Elahi FM, Knopman DS, Dickerson BC, Boeve BF, Gorno-Tempini ML, Spina S, Grinberg LT, Seeley WW, Miller BL, Kramer JH, Boxer AL, Rosen HJ

Cerebrospinal fluid biomarkers predict frontotemporal dementia trajectory.

Annals of clinical and translational neurology

Ljubenkov PA, Staffaroni AM, Rojas JC, Allen IE, Wang P, Heuer H, Karydas A, Kornak J, Cobigo Y, Seeley WW, Grinberg LT, Spina S, Fagan AM, Jerome G, Knopman D, Boeve BF, Dickerson BC, Kramer J, Miller B, Boxer AL, Rosen HJ

THE NIH-EXAMINER IS SENSITIVE TO COGNITIVE CHANGES IN ASYMPTOMATIC AND MILDLY SYMPTOMATIC FAMILIAL FRONTOTEMPORAL DEMENTIA.

Alzheimer's & Dementia

Adam M. Staffaroni, Lynn Bajorek, Peter Ljubenkov, Kaitlin Casaletto, Fanny Elahi, Katya Rascovsky, Bradley F. Boeve, Adam L. Boxer, Jessica Bove, Danielle Brushaber, Giovanni Coppola, Christina Dheel, Brad C. Dickerson, Julie A. Fields, Jamie Fong, Leah K. Forsberg, Ralitza H. Gavrilova, Debra Gearhart, Nupur Ghoshal, Jill Goldman, Jonathan Graff Radford, Neill R. Graff-Radford, Murray Grossman, Dana Haley, Hilary W. Heuer, John Hsiao, Ging-Yuek Robin Hsiung, Edward Huey, David J. Irwin, David T. Jones, Lynne Jones, Kejal Kantarci, Anna M. Karydas, David S. Knopman, John Kornak, Walter K. Kremers, Walter A. Kukull, Maria I. Lapid, Diane Lucente, Ian R. Mackenzie, Masood Manoochehri, Bruce L. Miller, Madeline Potter, Rosa Rademakers, Katherine Rankin, Margaret Sutherland, Jeremy Syrjanen, Joanne Taylor, Sandra Weintraub, Bonnie Wong, Zbigniew Wszolek, Howard J. Rosen, Joel H. Kramer, ARTFL/LEFFTDS Consortium

A Clinical Guide to Frontotemporal Dementias.

Focus (American Psychiatric Publishing)

Ljubenkov PA, Miller BL

Dementia.

Seminars in neurology

Ljubenkov PA, Geschwind MD