Raquel Gardner, MD

Assoc Professor in Residence

As a board-certified neurologist, Dr. Gardner evaluates and treats patients with various neurological disorders and provides them with follow-up care. As a fellowship-trained behavioral neurologist, Dr. Gardner has specific expertise in the evaluation and management of patients with neurodegenerative disorders such as dementia and mild cognitive impairment.

Her research program focuses on understanding the epidemiology and mechanisms of long-term sequelae of traumatic brain injury in older adults with the goal of improving outcomes in this vulnerable population. Her work is supported by the National Institutes of Neurological Disorders and Stroke, the Department of Defense, the American Federation for Aging Research, the Weill Institute for Neurosciences, and the UCSF Research Allocation Program.

Publications:

Traumatic Brain Injury and Risk of Neurodegenerative Disorder.

Biological psychiatry

Brett BL, Gardner RC, Godbout J, Dams-O'Connor K, Keene CD

Association of remote mild traumatic brain injury with cortical amyloid burden in clinically normal older adults.

Brain imaging and behavior

Asken BM, Mantyh WG, La Joie R, Strom A, Casaletto KB, Staffaroni AM, Apple AC, Lindbergh CA, Iaccarino L, You M, Grant H, Fonseca C, Windon C, Younes K, Tanner J, Rabinovici GD, Kramer JH, Gardner RC

Novel insights into risk of dementia after traumatic brain injury: A systematic review, meta-analysis, and heterogeneity analysis.

Alzheimer's & Dementia

Raquel C. Gardner, Amber L Bahorik, Paul Mangal, Isabel Elaine Allen, Kristine Yaffe

Feasibility and Utility of a Flexible Outcome Assessment Battery for Use in Longitudinal Traumatic Brain Injury Research.

Archives of physical medicine and rehabilitation

Yelena Bodien, Mark Sherer, Sabrina Taylor, Sureyya Dikmen, John Yue, Murray Stein, John Corrigan, Harvey Levin, Nancy Temkin, Joan Machamer, Kim Boase, Mary Vassar, Michael McCrea, Thomas McAllister, John Whyte, Jason Barber, Raquel Gardner, joel Kramer, Lindsay Nelson, Geoff Manley, Joseph Giacino

Prevalence of Lifetime History of Traumatic Brain Injury among Older Male Veterans Compared to Civilians: A Nationally Representative Study.

Journal of neurotrauma

Kornblith ES, Yaffe KC, Langa KM, Gardner RC

Physical and Functional Impairment Among Older Adults With a History of Traumatic Brain Injury.

The Journal of head trauma rehabilitation

Kornblith ES, Langa KM, Yaffe K, Gardner RC

Blood biomarkers of traumatic brain injury and cognitive impairment in older veterans.

Neurology

Peltz CB, Kenney K, Gill J, Diaz-Arrastia R, Gardner RC, Yaffe K

Screening for Lifetime History of Traumatic Brain Injury Among Older American and Irish Adults at Risk for Dementia: Development and Validation of a Web-Based Survey.

Journal of Alzheimer's disease : JAD

Gardner RC, Rivera E, O'Grady M, Doherty C, Yaffe K, Corrigan JD, Bogner J, Kramer J, Wilson F

Tau PET and multimodal brain imaging in patients at risk for chronic traumatic encephalopathy.

NeuroImage. Clinical

Lesman-Segev OH, La Joie R, Stephens ML, Sonni I, Tsai R, Bourakova V, Visani AV, Edwards L, O'Neil JP, Baker SL, Gardner RC, Janabi M, Chaudhary K, Perry DC, Kramer JH, Miller BL, Jagust WJ, Rabinovici GD

Linguistic and Cultural Acceptability of a Spanish Translation of the Ohio State University Traumatic Brain Injury Identification Method Among Community-Dwelling Spanish-Dominant Older Adults.

Archives of Rehabilitation Research and Clinical Translation

Hufstedler HC, Dorsman KA, Rivera EJ, Lanata SC, Bogner JA, Corrigan JD, Fuller SM, Borja XR, Wilson F, Gardner RC

AGENT ORANGE EXPOSURE AND DEMENTIA DIAGNOSIS IN VIETNAM VETERANS: A CHRONIC EFFECTS OF NEUROTRAUMA CONSORTIUM STUDY.

Alzheimer's & Dementia

Deborah E. Barnes, Yixia Li, Amy L. Byers, Raquel C. Gardner, Carrie Peltz, Kristine Yaffe

COGNITIVE DECLINE ONE YEAR AFTER MILD TRAUMATIC BRAIN INJURY: A TRACK-TBI STUDY.

Alzheimer's & Dementia

Raquel C. Gardner, Russell Huie, Adam Ferguson, Kristine Yaffe, Geoffrey T. Manley, TRACK-TBI Investigators

Neuropathological correlates of structural and functional imaging biomarkers in 4-repeat tauopathies.

Brain : a journal of neurology

Spina S, Brown JA, Deng J, Gardner RC, Nana AL, Hwang JL, Gaus SE, Huang EJ, Kramer JH, Rosen HJ, Kornak J, Neuhaus J, Miller BL, Grinberg LT, Boxer AL, Seeley WW

PRE-INJURY MILD COGNITIVE IMPAIRMENT IN OLDER ADULTS PRESENTING ACUTELY WITH TRAUMATIC BRAIN INJURY: THE TRANSFORMING RESEARCH AND CLINICAL KNOWLEDGE IN GERIATRIC TBI PILOT STUDY (TRACK-GERI PILOT).

Alzheimer's & Dementia

Michele Diaz, Chelsea Camara, Molly Rose Morrissey, Geoffrey T. Manley, Raquel C. Gardner

THE PREVALENCE AND ATTRIBUTABLE RISK OF COMMON IMPORTANT RISK FACTORS TO INFORM STRATEGIES FOR THE POPULATION-BASED PREVENTION OF DEMENTIA IN SOUTH AFRICA.

Alzheimer's & Dementia

Kirsten Bobrow, Raquel C. Gardner, Deborah E. Barnes, Kristine Yaffe

Divergent 6-Month Functional Recovery Trajectories and Predictors after Traumatic Brain Injury: Novel Insights from the COBRIT Study.

Journal of neurotrauma

Gardner RC, Cheng J, Ferguson AR, Boylan R, Boscardin WJ, Zafonte RD, Manley GT, Bagiella E, Ansel BM, Novack TA, Friedewald WT, Hesdorffer DC, Timmons S, Jallo J, Eisenberg H, Hart T, Ricker JH, Diaz-Arrastia R, Merchant R, Temkin NR, Melton S, Dikmen S, Okonkwo DO

Age and sex-mediated differences in six-month outcomes after mild traumatic brain injury in young adults: a TRACK-TBI study.

Neurological research

Yue JK, Levin HS, Suen CG, Morrissey MR, Runyon SJ, Winkler EA, Puffer RC, Deng H, Robinson CK, Rick JW, Phelps RRL, Sharma S, Taylor SR, Vassar MJ, Cnossen MC, Lingsma HF, Gardner RC, Temkin NR, Barber J, Dikmen SS, Yuh EL, Mukherjee P, Stein MB, Cage TA, Valadka AB, Okonkwo DO, Manley GT

Pre-injury Comorbidities Are Associated With Functional Impairment and Post-concussive Symptoms at 3- and 6-Months After Mild Traumatic Brain Injury: A TRACK-TBI Study.

Frontiers in neurology

Yue JK, Cnossen MC, Winkler EA, Deng H, Phelps RRL, Coss NA, Sharma S, Robinson CK, Suen CG, Vassar MJ, Schnyer DM, Puccio AM, Gardner RC, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Lingsma HF, Manley GT

Traumatic brain injury in older adults: do we need a different approach?

Concussion (London, England)

Peters ME, Gardner RC

Association of Mild Traumatic Brain Injury With and Without Loss of Consciousness With Dementia in US Military Veterans.

JAMA neurology

Barnes DE, Byers AL, Gardner RC, Seal KH, Boscardin WJ, Yaffe K

EARLY COGNITIVE DECLINE WITHIN ONE YEAR AFTER TRAUMATIC BRAIN INJURY: A TRACK-TBI STUDY.

Alzheimer's & Dementia

Raquel C. Gardner, Lindsay D. Nelson, John K. Yue, Alex B. Valadka, Michael A. McCrea, Joseph T. Giacino, Geoffrey T. Manley, TRACK-TBI Investigators

THE NATIONAL ALZHEIMER’S COORDINATING CENTER UNIFORM DATA SET TRAUMATIC BRAIN INJURY (TBI) EXPOSURE SCREEN MISSES MORE THAN HALF OF TBI EXPOSURES IDENTIFIED USING A COMPREHENSIVE TBI INTERVIEW.

Alzheimer's & Dementia

Raquel C. Gardner, Ernesto Rivera, Kristine Yaffe, Joel H. Kramer

THE ROLE OF TRAUMATIC BRAIN INJURY IN THE DEVELOPMENT OF DEMENTIA: VALIDATION OF A WEB-BASED SELF-ADMINISTERED TRAUMATIC BRAIN INJURY EXPOSURE SURVEY FOR USE IN COGNITIVE AGING RESEARCH.

Alzheimer's & Dementia

Raquel C. Gardner, Ernesto Rivera, Megan O'Grady, Colin Doherty, Kristine Yaffe, Joel H. Kramer, Fiona Wilson

Age-Related Differences in Diagnostic Accuracy of Plasma GFAP and Tau For Identifying Acute Intracranial Trauma on CT: A TRACK-TBI Study.

Journal of neurotrauma

Gardner RC, Rubenstein R, Wang KKW, Korley FK, Yue JK, Yuh EL, Mukherjee P, Valadka A, Okonkwo DO, Diaz-Arrastia R, Manley G

Concordance of common data elements for assessment of subjective cognitive complaints after mild-traumatic brain injury: a TRACK-TBI Pilot Study.

Brain injury

Ngwenya LB, Gardner RC, Yue JK, Burke JF, Ferguson AR, Huang MC, Winkler EA, Pirracchio R, Satris GG, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Manley GT

Mild TBI and risk of Parkinson disease: A Chronic Effects of Neurotrauma Consortium Study.

Neurology

Gardner RC, Byers AL, Barnes DE, Li Y, Boscardin J, Yaffe K

Geriatric Traumatic Brain Injury: Epidemiology, Outcomes, Knowledge Gaps, and Future Directions.

Journal of neurotrauma

Gardner RC, Dams-O'Connor K, Morrissey MR, Manley GT

Preinjury employment status as a risk factor for symptomatology and disability in mild traumatic brain injury: A TRACK-TBI analysis.

NeuroRehabilitation

Yue JK, Rick JW, Morrissey MR, Taylor SR, Deng H, Suen CG, Vassar MJ, Cnossen MC, Lingsma HF, Yuh EL, Mukherjee P, Gardner RC, Valadka AB, Okonkwo DO, Cage TA, Manley GT

Remote Traumatic Brain Injury Is Associated with Motor Dysfunction in Older Military Veterans.

The journals of gerontology. Series A, Biological sciences and medical sciences

Gardner RC, Peltz CB, Kenney K, Covinsky KE, Diaz-Arrastia R, Yaffe K

FUNCTIONAL STATUS OF NON-DEMENTED COMMUNITY-DWELLING OLDER ADULTS WITH PRIOR TRAUMATIC BRAIN INJURY.

Innovation in aging

R.C. Gardner, K.M. Langa, K. Yaffe

TRAUMATIC BRAIN INJURY (TBI) SEVERITY AND AGE OF DEMENTIA DIAGNOSIS AMONG VETERANS.

Alzheimer's & Dementia

Deborah E. Barnes, Raquel C. Gardner, Amy Byers, Karen Seal, W John Boscardin, Kristine Yaffe, Chronic Effects of Neurotrauma Consortium Study Group

The Traumatic Brain Injury Endpoints Development (TED) Initiative: Progress on a Public-Private Regulatory Collaboration to Accelerate Diagnosis and Treatment of Traumatic Brain Injury.

Journal of neurotrauma

Manley GT, MacDonald CL, Markowitz A, Stephenson D, Robbins A, Gardner RC, Winkler EA, Bodien Y, Taylor S, Yue JK, Kannan L, Kumar A, McCrea M, Wang KKW

Subjective and objective cognitive function among older adults with a history of traumatic brain injury: A population-based cohort study.

PLoS medicine

Gardner RC, Langa KM, Yaffe K

Chronic traumatic encephalopathy.

The Behavioral Neurology of Dementia

Raquel C. Gardner, David C. Perry

Neurobehavioral Characteristics of Older Veterans With Remote Traumatic Brain Injury.

The Journal of head trauma rehabilitation

Peltz CB, Gardner RC, Kenney K, Diaz-Arrastia R, Kramer JH, Yaffe K

Timing and significance of pathological features in C9orf72 expansion-associated frontotemporal dementia.

Brain : a journal of neurology

Vatsavayai SC, Yoon SJ, Gardner RC, Gendron TF, Vargas JN, Trujillo A, Pribadi M, Phillips JJ, Gaus SE, Hixson JD, Garcia PA, Rabinovici GD, Coppola G, Geschwind DH, Petrucelli L, Miller BL, Seeley WW

PRIOR TRAUMATIC BRAIN INJURY IS ASSOCIATED WITH SUBJECTIVE BUT NOT OBJECTIVE MEMORY IMPAIRMENT AMONG NON-DEMENTED OLDER ADULTS IN THE HEALTH AND RETIREMENT STUDY.

Alzheimer's & Dementia

Raquel C. Gardner, Kenneth M. Langa, Kristine Yaffe

COMT Val 158 Met polymorphism is associated with nonverbal cognition following mild traumatic brain injury.

Neurogenetics

Winkler EA, Yue JK, McAllister TW, Temkin NR, Oh SS, Burchard EG, Hu D, Ferguson AR, Lingsma HF, Burke JF, Sorani MD, Rosand J, Yuh EL, Barber J, Tarapore PE, Gardner RC, Sharma S, Satris GG, Eng C, Puccio AM, Wang KK, Mukherjee P, Valadka AB, Okonkwo DO, Diaz-Arrastia R, Manley GT

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Raquel Gardner, MD