Kaitlin Casaletto, PhD

Associate Professor
[email protected]
+1 415 476-1883
Fields of Interest: 
Healthy Aging
Neuroinflammation
Neuropsychology

Dr. Kaitlin Casaletto is a scientist-practitioner, board-certified neuropsychologist, and Associate Professor at the UC San Francisco Memory and Aging Center (MAC). She leads a research program identifying novel biobehavioral targets of dementia prevention. Her work has a particular lens towards sex differences and translational study designs that leverage proteomic and digital health approaches to identify targets of cognitive resilience to aging.

Dr. Casaletto obtained her Ph.D. in Clinical Psychology from the UCSD/SDSU Joint Doctoral Program and completed her fellowship in Neuropsychology at the UCSF Memory and Aging Center in the Department of Neurology.

Publications: 

Better cardiovascular health is associated with slowed clinical progression in autosomal dominant frontotemporal lobar degeneration variant carriers.

Alzheimer's & dementia : the journal of the Alzheimer's Association

VandeBunte AM, Lee H, Paolillo EW, Hsiung GR, Staffaroni AM, Saloner R, Tartaglia C, Yaffe K, Knopman DS, Ramos EM, Rascovsky K, Bozoki AC, Wong B, Domoto-Reilly K, Snyder A, Pressman P, Mendez MF, Litvan I, Fields JA, Galasko DR, Darby R, Masdeu JC, Pasqual MB, Honig LS, Ghoshal N, Appleby BS, Mackenzie IR, Heuer HW, Kramer JH, Boxer AL, Forsberg LK, Boeve B, Rosen HJ, Casaletto KB, ALLFTD Consortium

Clinical implications of head trauma in frontotemporal dementia and primary progressive aphasia.

Alzheimer's research & therapy

Asken BM, Bove JM, Bauer RM, Tanner JA, Casaletto KB, Staffaroni AM, VandeVrede L, Alosco ML, Mez JB, Stern RA, Miller BL, Grinberg LT, Boxer AL, Gorno-Tempini ML, Rosen HJ, Rabinovici GD, Kramer JH

Predicting brain atrophy and cognitive aging trajectories with baseline subjective cognitive concerns in cognitively normal older adults.

Neurobiology of aging

You M, Lindbergh CA, La Joie R, Paolillo EW, Saloner R, Diaz V, Cotter DL, Walters S, Altendahl M, Staffaroni AM, Kramer JH, Gaynor LS, Casaletto KB

Sex and gender differences in cognitive resilience to aging and Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Arenaza-Urquijo EM, Boyle R, Casaletto K, Anstey KJ, Vila-Castelar C, Colverson A, Palpatzis E, Eissman JM, Kheng Siang Ng T, Raghavan S, Akinci M, Vonk JMJ, Machado LS, Zanwar PP, Shrestha HL, Wagner M, Tamburin S, Sohrabi HR, Loi S, Bartrés-Faz D, Dubal DB, Prashanthi V, Okonkwo O, Hohman TJ, Ewers M, Buckley RF, Reserve, Resilience and Protective Factors Professional Interest Area, Sex and Gender Professional I

Visual Impairment, Eye Conditions, and Diagnoses of Neurodegeneration and Dementia.

JAMA network open

Ferguson EL, Thoma M, Buto PT, Wang J, Glymour MM, Hoffmann TJ, Choquet H, Andrews SJ, Yaffe K, Casaletto K, Brenowitz WD

Examining Associations Between Smartphone Use and Clinical Severity in Frontotemporal Dementia: Proof-of-Concept Study.

JMIR aging

Paolillo EW, Casaletto KB, Clark AL, Taylor JC, Heuer HW, Wise AB, Dhanam S, Sanderson-Cimino M, Saloner R, Kramer JH, Kornak J, Kremers W, Forsberg L, Appleby B, Bayram E, Bozoki A, Brushaber D, Darby RR, Day GS, Dickerson BC, Domoto-Reilly K, Elahi F, Fields JA, Ghoshal N, Graff-Radford N, G H Hall M, Honig LS, Huey ED, Lapid MI, Litvan I, Mackenzie IR, Masdeu JC, Mendez MF, Mester C, Miyagawa T, Naasan G, Pascual B, Pressman P, Ramos EM, Rankin KP, Rexach J, Rojas JC, VandeVrede L, Wong B, Wszolek ZK, Boeve BF, Rosen HJ, Boxer AL, Staffaroni AM, ALLFTD Consortium

Associations of cerebrovascular disease and Alzheimer's disease pathology with cognitive decline: Analysis of the National Alzheimer's Coordinating Center Uniform Data Set.

Neurobiology of aging

Chatterjee A, Lee S, Diaz V, Saloner R, Sanderson-Cimino M, deCarli C, Maillard P, Hinman J, Vossel K, Casaletto KB, Staffaroni AM, Paolillo EW, Kramer JH

Targeting complement C3a receptor resolves mitochondrial hyperfusion and subretinal microglial activation in progranulin-deficient frontotemporal dementia.

bioRxiv : the preprint server for biology

Tan LX, Oertel FC, Cheng A, Cobigo Y, Keihani A, Bennett DJ, Abdelhak A, Montes SC, Chapman M, Chen RY, Cordano C, Ward ME, Casaletto K, Kramer JH, Rosen HJ, Boxer A, Miller BL, Green AJ, Elahi FM, Lakkaraju A

Unveiling the proteome-wide autoreactome enables enhanced evaluation of emerging CAR-T therapies in autoimmunity.

The Journal of clinical investigation

Bodansky A, Yu DJ, Rallistan AN, Kalaycioglu M, Boonyaratanakornkit J, Green DJ, Gauthier J, Turtle CJ, Zorn KC, O'Donovan B, Mandel-Brehm C, Asaki J, Kortbawi H, Kung AF, Rackaityte E, Wang CY, Saxena A, de Dios K, Masi G, Nowak RJ, O'Connor KC, Li H, Diaz VE, Saloner R, Casaletto KB, Gontrum EQ, Chan BJ, Kramer JH, Wilson MR, Utz PJ, Hill JA, Jackson SW, Anderson MS, DeRisi JL

Development and validation of a nonverbal consensus-based semantic memory paradigm in patients with epilepsy.

Journal of the International Neuropsychological Society : JINS

Tran EB, Vonk JMJ, Casaletto K, Zhang D, Christin R, Marathe S, Gorno-Tempini ML, Chang EF, Kleen JK

Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration.

Research square

Saloner R, Staffaroni A, Dammer E, Johnson ECB, Paolillo E, Wise A, Heuer H, Forsberg L, Lago AL, Webb J, Vogel J, Santillo A, Hansson O, Kramer J, Miller B, Li J, Loureiro J, Sivasankaran R, Worringer K, Seyfried N, Yokoyama J, Seeley W, Spina S, Grinberg L, VandeVrede L, Ljubenkov P, Bayram E, Bozoki A, Brushaber D, Considine C, Day G, Dickerson B, Domoto-Reilly K, Faber K, Galasko D, Geschwind D, Ghoshal N, Graff-Radford N, Hales C, Honig L, Hsiung GY, Huey E, Kornak J, Kremers W, Lapid M, Lee S, Litvan I, McMillan C, Mendez M, Miyagawa T, Pantelyat A, Pascual B, Paulson H, Petrucelli L, Pressman P, Ramos E, Rascovsky K, Roberson E, Savica R, Snyder A, Sullivan AC, Tartaglia C, Vandebergh M, Boeve B, Rosen H, Rojas J, Boxer A, Casaletto K

Neuropsychiatric profiles and cerebral amyloid burden in adults without dementia.

Dementia and geriatric cognitive disorders

Gontrum EQ, Paolillo EW, Lee S, Diaz V, Ehrenberg A, Saloner R, Mundada NS, La Joie R, Rabinovici G, Kramer JH, Casaletto K

Linking Type and Extent of Head Trauma to Cavum Septum Pellucidum in Older Adults With and Without Alzheimer Disease and Related Dementias.

Neurology

Asken BM, Tanner JA, Vandevrede L, Apple A, Chapleau M, Gaynor LS, Lane-Donovan C, Lenio S, Yadollahikhales G, Lee S, Gontrum E, Knudtson M, Iaccarino L, La Joie R, Cobigo Y, Staffaroni AM, Casaletto KB, Gardner RC, Grinberg LT, Gorno-Tempini ML, Rosen HJ, Seeley WW, Miller BL, Kramer J, Rabinovici GD

Sex Differences in Association of Physical Activity With All-Cause and Cardiovascular Mortality.

Journal of the American College of Cardiology

Ji H, Gulati M, Huang TY, Kwan AC, Ouyang D, Ebinger JE, Casaletto K, Moreau KL, Skali H, Cheng S

KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.

The Journal of clinical investigation

Kauwe G, Pareja-Navarro KA, Yao L, Chen JH, Wong I, Saloner R, Cifuentes H, Nana AL, Shah S, Li Y, Le D, Spina S, Grinberg LT, Seeley WW, Kramer JH, Sacktor TC, Schilling B, Gan L, Casaletto KB, Tracy TE

Non-REM stage 3 sleep disruption across the spectrum of AD severity: from cognitively unimpaired to dementia.

Sleep medicine

L. Yack, C.M. Walsh, N. Falgàs, N. Pandher, Q. Coppola, F. Song, A.J. Simon, M. Tucker, R. Saloner, K. Casaletto, J.H. Kramer, M. Gorno Tempini, H. Rosen, G.D. Rabinovici, L.T. Grinberg, T.C. Neylan

Associations of Polycystic Ovary Syndrome With Indicators of Brain Health at Midlife in the CARDIA Cohort.

Neurology

Huddleston HG, Jaswa EG, Casaletto KB, Neuhaus J, Kim C, Wellons M, Launer LJ, Yaffe K

Cataracts are associated with smaller gray matter brain volume among participants in the UK Biobank.

Alzheimer's & Dementia

Erin L Ferguson, Peter Buto, Mary Thoma, Jingxuan Wang, M. Maria Glymour, Thomas J. Hoffmann, Hélène Choquet, Shea J Andrews, Kristine Yaffe, Kaitlin B. Casaletto, Willa D Brenowitz

Leveraging Large-scale CSF Proteomics to identify Disease Progression Biomarkers in Autosomal Dominant Frontotemporal Lobar Degeneration.

Alzheimer's & Dementia

Rowan Saloner, Adam M. Staffaroni, Eric B. Dammer, Erik C.B. Johnson, Emily W. Paolillo, Hilary W. Heuer, Amy B. Wise, Leah K. Forsberg, Joel H. Kramer, Bruce L Miller, Jingyao Li, Joseph Loureiro, Rajeev Sivasankaran, Katie Worringer, Brad F. Boeve, Howard J. Rosen, Adam L. Boxer, Julio C. Rojas, Kaitlin B. Casaletto

Life’s Simple 7 Relates to Better Cognitive and Brain Health in Individuals with Autosomal Dominant Frontotemporal Dementia.

Alzheimer's & Dementia

Anna M VandeBunte, Joel H. Kramer, Kaitlin B. Casaletto, Emily W. Paolillo, Rowan Saloner, Hyunwoo Lee, Ging-Yuek Robin Hsiung, Adam M. Staffaroni, Shannon Y. Lee, Carmela Tartaglia, Hilary W. Heuer, Brad F. Boeve, Adam L. Boxer, Howard J. Rosen

Neurophysiological changes associated with plasma p-tau represent functional effects of amyloid accumulation and are modulated by APOE.

Alzheimer's & Dementia

Kamalini G Ranasinghe, Julio C. Rojas, Kaitlin B. Casaletto, Kiwamu Kudo, Faatimah Syed, Renaud La Joie, Brandon Chan, Argentina Lario Lago, Bruce L Miller, Keith Vossel, Joel H. Kramer, Adam L. Boxer, Katherine P Rankin, Gil D. Rabinovici, Srikantan S Nagarajan

Passively monitored smartphone battery percentage relates to disease severity in frontotemporal dementia: A proof-of-concept study.

Alzheimer's & Dementia

Emily W. Paolillo, Kaitlin B. Casaletto, Annie L Clark, Jack C Taylor, Hilary W. Heuer, Amy B. Wise, Sreya Dhanam, Mark E. Sanderson-Cimino, Rowan Saloner, Joel H. Kramer, John Kornak, Walter K. Kremers, Leah K. Forsberg, Brad F. Boeve, Howard J. Rosen, Adam L. Boxer, Adam M. Staffaroni, the ALLFTD Consortium

Plasma rejuvenation factor GDF11 associates with amyloid-related cognitive decline in older adults across the Alzheimer’s Disease spectrum.

Alzheimer's & Dementia

Shannon Y. Lee, Emily W. Paolillo, Rowan Saloner, Anna M VandeBunte, Gil D. Rabinovici, Renaud La Joie, Joel H. Kramer, Saul Villeda, Kaitlin B. Casaletto

The Role of Alzheimer’s Disease Pathology in Cognition, Brain Volume, and Plasma Biomarker Concentrations in Traumatic Encephalopathy Syndrome.

Alzheimer's & Dementia

Breton M. Asken, Jeremy A. Tanner, Lawren VandeVrede, William G Mantyh, Kaitlin B. Casaletto, Adam M. Staffaroni, David N. soleimani-Meigooni, Leslie S Gaynor, Corrina S. Fonseca, Ranjani Shankar, Harli E. Grant, Karen Smith, Argentina Lario Lago, Haiyan Xu, Renaud La Joie, Yann Cobigo, Howard J. Rosen, David C. Perry, Julio C. Rojas, Lea T. Grinberg, Bruce L Miller, Raquel C. Gardner, Kevin K.W. Wang, Joel H. Kramer, Gil D. Rabinovici

Unveiling the autoreactome: Proteome-wide immunological fingerprints reveal the promise of plasma cell depleting therapy.

medRxiv : the preprint server for health sciences

Bodansky A, Yu DJ, Rallistan A, Kalaycioglu M, Boonyaratanakornkit J, Green DJ, Gauthier J, Turtle CJ, Zorn K, O'Donovan B, Mandel-Brehm C, Asaki J, Kortbawi H, Kung AF, Rackaityte E, Wang CY, Saxena A, de Dios K, Masi G, Nowak RJ, O'Connor KC, Li H, Diaz VE, Casaletto KB, Gontrum EQ, Chan B, Kramer JH, Wilson MR, Utz PJ, Hill JA, Jackson SW, Anderson MS, DeRisi JL

Multimodal lifestyle engagement patterns support cognitive stability beyond neuropathological burden.

Alzheimer's research & therapy

Paolillo EW, Saloner R, VandeBunte A, Lee S, Bennett DA, Casaletto KB

1 Sex Differences in Associations Between APOE e2 and Longitudinal Cognitive Decline.

Journal of the International Neuropsychological Society

Madeline Wood, Lisa Xiong, Yuen Yan Wong, Rachel F Buckley, Walter Swardfager, Mario Masellis, Andrew Lim, Emma Nichols, Renaud La Joie, Kaitlin Casaletto, Raj Kumar, Kristen Dams-O’Connor, Priya Palta, Kristen George, Claudia Satizabal, Lisa L Barnes, Julie A Schneider, Judy Pa, Adam Brickman, Sandra Black, Jennifer Rabin

5 Rejuvenating Blood Factor TIMP2 Relates to Physical Activity and Cognitive Functioning in Older Adults on The Alzheimer’s Disease Continuum.

Journal of the International Neuropsychological Society

Emily W Paolillo, Shannon Y Lee, Anna M Vandebunte, Rowan Saloner, Leslie S Gaynor, Joel H Kramer, Kaitlin B Casaletto

50 Effects of Cerebrovascular Risk Factors and Alzheimer’s Disease Pathology on Executive Function and Memory Changes: Analysis of the National Alzheimer’s Coordinating Center Cohort.

Journal of the International Neuropsychological Society

Ankita Chatterjee, Shannon Lee, Valentina Diaz, Kaitlin B Casaletto, Adam M Staffaroni, Joel H Kramer

57 Validation of a List Learning Task for Monolingual Spanish Speaking Older Adults.

Journal of the International Neuropsychological Society

Valentina E Diaz, Lucia Lopez, Gloria Aguirre, Karen A Dorsman, Anne-Marie Rodriguez, Jorge Archila Puac, Shannon Lee, Stefanie D Pina-Escudero, Serggio Lanata, Kaitlin Casaletto, Joel H Kramer

6 The Moderating Role of Physical Activity on Hippocampal Iron Deposition and Memory Outcomes in Typically Aging Older Adults.

Journal of the International Neuropsychological Society

Shannon Y Lee, Emily W Paolillo, Rowan Saloner, Torie Tsuei, Anna VandeBunte, Joel H Kramer, Kaitlin B Casaletto

73 Sex Differences in Verbal Memory and Alzheimer’s Disease Biomarkers in Clinically Normal Older Adults: Role of SNAP-25 Genetics.

Journal of the International Neuropsychological Society

Rowan Saloner, Emily W Paolillo, Kevin J Wojta, Corrina Fonseca, Eva Q Gontrum, Argentina Lario-Lago, Gil D Rabinovici, Jennifer S Yokoyama, Jessica E Rexach, Joel H Kramer, Kaitlin B Casaletto

93 Impact of Cardiovascular Risk on Cognitive and Brain Aging in Autosomal Dominant Frontotemporal Dementia.

Journal of the International Neuropsychological Society

Anna M VandeBunte, Emily W Paolillo, Hyunwoo Lee, Ging-Yuek Robin Hsiung, Adam Staffaroni, Shannon Y Lee, Carmela Tartaglia, Hilary Heur, Joel H Kramer, Brad Boeve, Adam Boxer, Howie Rosen, Kaitlin B Casaletto

Plasma phosphorylated tau-217 exhibits sex-specific prognostication of cognitive decline and brain atrophy in cognitively unimpaired adults.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Saloner R, VandeVrede L, Asken BM, Paolillo EW, Gontrum EQ, Wolf A, Lario-Lago A, Milà-Alomà M, Triana-Baltzer G, Kolb HC, Dubal DB, Rabinovici GD, Miller BL, Boxer AL, Casaletto KB, Kramer JH

Moderating role of physical activity on hippocampal iron deposition and memory outcomes in typically aging older adults.

Neurobiology of aging

Lee SY, Paolillo EW, Saloner R, Cobigo Y, Diaz VE, Gontrum EQ, VandeBunte A, Chatterjee A, Tucker M, Kramer JH, Casaletto KB

Alzheimer's pathology is associated with altered cognition, brain volume, and plasma biomarker patterns in traumatic encephalopathy syndrome.

Alzheimer's research & therapy

Asken BM, Tanner JA, Gaynor LS, VandeVrede L, Mantyh WG, Casaletto KB, Staffaroni AM, Fonseca C, Shankar R, Grant H, Smith K, Lago AL, Xu H, La Joie R, Cobigo Y, Rosen H, Perry DC, Rojas JC, Miller BL, Gardner RC, Wang KKW, Kramer JH, Rabinovici GD

Sexually dimorphic differences in angiogenesis markers predict brain aging trajectories.

bioRxiv : the preprint server for biology

Torres-Espin A, Rabadaugh H, Fitzsimons S, Harvey D, Chou A, Lindberg C, Casaletto KB, Goldberger L, Staffaroni AM, Maillard P, Miller BL, DeCarli C, Hinman JD, Ferguson AR, Kramer JH, Elahi FM

Independent associations of plasma Aß42 and plasma neurofilament light with white matter hyperintensity volume in non-demented older individuals.

Alzheimer's & Dementia

Ankita Chatterjee, Rowan Saloner, Breton M. Asken, Brandon Chan, Argentina Lario Lago, Kaitlin B. Casaletto, Fanny M Elahi, Torie Tsuei, Julio C. Rojas, Joel H. Kramer

Sex differences in plasma phosphorylated-tau181 vary between older adults with and without mild cognitive impairment.

Alzheimer's & Dementia

Miwa Tucker, Joel H. Kramer, Kaitlin B. Casaletto, Eva Q. Gontrum, Argentina Lario Lago, Julio C. Rojas, Rowan Saloner, Brandon Chan

KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.

bioRxiv : the preprint server for biology

Kauwe G, Pareja-Navarro KA, Yao L, Chen JH, Wong I, Saloner R, Cifuentes H, Nana AL, Shah S, Li Y, Le D, Spina S, Grinberg LT, Seeley WW, Kramer JH, Sacktor TC, Schilling B, Gan L, Casaletto KB, Tracy TE

Data-driven physical actigraphy patterns relate to cognitive and vascular health in older adults.

Experimental gerontology

Paolillo EW, Lee SY, VandeBunte A, Saloner R, Gaynor LS, Djukic N, Tsuei T, Cobigo Y, Kramer JH, Casaletto KB

Sex differences in associations between APOE e2 and longitudinal cognitive decline.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Wood ME, Xiong LY, Wong YY, Buckley RF, Swardfager W, Masellis M, Lim ASP, Nichols E, Joie R, Casaletto KB, Kumar RG, Dams-O'Connor K, Palta P, George KM, Satizabal CL, Barnes LL, Schneider JA, Binet AP, Villeneuve S, Pa J, Brickman AM, Black SE, Rabin JS, ADNI and Prevent-AD Research Groups

Plasma inflammation for predicting phenotypic conversion and clinical progression of autosomal dominant frontotemporal lobar degeneration.

Journal of neurology, neurosurgery, and psychiatry

Asken BM, Ljubenkov PA, Staffaroni AM, Casaletto KB, Vandevrede L, Cobigo Y, Rojas-Rodriguez JC, Rankin KP, Kornak J, Heuer H, Shigenaga J, Appleby BS, Bozoki AC, Domoto-Reilly K, Ghoshal N, Huey E, Litvan I, Masdeu JC, Mendez MF, Pascual B, Pressman P, Tartaglia MC, Kremers W, Forsberg LK, Boeve BF, Boxer AL, Rosen HJ, Kramer JH, ALLFTD Consortium Investigators

Sex-specific effects of SNAP-25 genotype on verbal memory and Alzheimer's disease biomarkers in clinically normal older adults.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Saloner R, Paolillo EW, Wojta KJ, Fonseca C, Gontrum EQ, Lario-Lago A, Rabinovici GD, Yokoyama JS, Rexach JE, Kramer JH, Casaletto KB

Regional Vulnerability of the Corpus Callosum in the Context of Cardiovascular Risk.

Journal of geriatric psychiatry and neurology

VandeBunte AM, Fonseca C, Paolillo EW, Gontrum E, Lee SY, Kramer JH, Casaletto KB

Association of Physical Activity With Neurofilament Light Chain Trajectories in Autosomal Dominant Frontotemporal Lobar Degeneration Variant Carriers.

JAMA neurology

Casaletto KB, Kornack J, Paolillo EW, Rojas JC, VandeBunte A, Staffaroni AS, Lee S, Heuer H, Forsberg L, Ramos EM, Miller BL, Kramer JH, Yaffe K, Petrucelli L, Boxer A, Boeve B, Gendron TF, Rosen H, ALLFTD Consortium

APOE Genotype Moderates the Relationship Between Plasma Phosphorylated-tau181 and Pattern Separation Performance in Non-demented Adults.

Alzheimer's & Dementia

Valentina E Diaz, Molly B Memel, Leslie S Gaynor, Eva Q. Gontrum, Brandon Chan, Argentina Lario Lago, Michael A. Yassa, Julio C. Rojas, Kaitlin B Casaletto, Joel H. Kramer, Rowan Saloner

Alzheimer’s Disease Proteinopathy and Synaptic Integrity: The Protective Role of Physical Activity.

Alzheimer's & Dementia

Shannon Y. Lee, Emily W Paolillo, Anna M. VandeBunte, Ann Brinkmalm, Kaj Blennow, Henrik Zetterberg, Joel H. Kramer, Kaitlin B Casaletto

Blood-brain barrier dysfunction is associated with A/T/N biomarkers and cognition in the aging brain.

Alzheimer's & Dementia

Yasmine Tabdili, Krystal Courtney D Belmonte, Nivetha Brathaban, Emma Iorio, Ryan Park, Anna M VandeBunte, Kaitlin B Casaletto, Joel H. Kramer, Katerina Akassoglou, Fanny M Elahi

Cerebral amyloid angiopathy interacts with parenchymal beta-amyloid to promote tau and cognitive decline.

Alzheimer's & Dementia

Jennifer S. Rabin, Emma Nichols, Renaud La Joie, Kaitlin B Casaletto, Priya Palta, Kristen Dams-O'Connor, Raj G. Kumar, Kristen M. George, Claudia L Satizabal, Julie A Schneider, Judy Pa, Adam M. Brickman

Latent profiles of physical actigraphy patterns among older adults: Differential relationships with cognition and vascular burden by sex.

Alzheimer's & Dementia

Emily W Paolillo, Shannon Y. Lee, Nina Djukic, Anna M. VandeBunte, Rowan Saloner, Joel H. Kramer, Kaitlin B Casaletto

Physical Activity Relates to Lower Astrocytic Activation and Axonal Breakdown in Clinically Normal Older Adults.

Alzheimer's & Dementia

Anna M VandeBunte, Shannon Y. Lee, Emily W Paolillo, Julio C. Rojas, Brandon Chan, Argentina Lario Lago, Joel H. Kramer, Kaitlin B Casaletto

Plasma glial fibrillary acidic protein as a moderator along the Alzheimer’s disease biomarker cascade.

Alzheimer's & Dementia

Rowan Saloner, Breton M. Asken, Eva Q. Gontrum, Brandon Chan, Argentina Lario Lago, Julio C. Rojas, Bruce L. Miller, Gil D. Rabinovici, Kaitlin B Casaletto, Joel H. Kramer

Plasma phosphorylated-tau181 is an indicator of early manifestations of neuropsychiatric symptoms in younger subclinical individuals.

Alzheimer's & Dementia

Eva Q. Gontrum, Rowan Saloner, Brandon Chan, Argentina Lario Lago, Julio C. Rojas, Kaitlin B Casaletto, Joel H. Kramer

Sex modifies the association between hippocampal blood flow and episodic memory in cognitively unimpaired individuals.

Alzheimer's & Dementia

Anna Brugulat-Serrat, Yann Cobigo, Corrina S. Fonseca, Torie Tsuei, Lauren Goldberger, Howard J. Rosen, Joel H. Kramer, Fanny M Elahi, Adam M. Staffaroni, Kaitlin B Casaletto

Sex-specific mediational effects of microglial activation on Alzheimer’s disease proteinopathy in older adults.

Alzheimer's & Dementia

Kaitlin B Casaletto, Emma Nichols, Vahan Aslanyan, Stephanie M. Simone, Jennifer S. Rabin, Renaud La Joie, Adam M. Brickman, Kristen Dams-O'Connor, Priya Palta, Raj G. Kumar, Kristen M. George, Claudia L Satizabal, Julie A Schneider, Judy Pa

Spectral signatures associated with cognitive aging, APOE4, amyloid-ß and measures of axonal integrity in cognitively unimpaired adults.

Alzheimer's & Dementia

Kamalini G Ranasinghe, Kaitlin B Casaletto, Kiwamu Kudo, Hannah M Lerner, Danielle Mizuiri, Renaud La Joie, Bruce L. Miller, Keith Vossel, Joel H. Kramer, William J. Jagust, Katherine P Rankin, Gil D. Rabinovici, Srikantan S Nagarajan

AD and non-AD mediators of the pathway between the APOE genotype and cognition.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Nichols E, Brickman AM, Casaletto KB, Dams-O'Connor K, George KM, Kumar RG, Palta P, Rabin JS, Satizabal CL, Schneider J, Pa J, La Joie R

Sex Differences in the Relationship between Perceived Stress and Cognitive Trajectories.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Paolillo EW, You M, Gontrum E, Saloner R, Gaynor LS, Kramer JH, Casaletto KB

Combined Effects of Synaptic and Axonal Integrity on Longitudinal Gray Matter Atrophy in Cognitively Unimpaired Adults.

Neurology

Saloner R, Fonseca C, Paolillo EW, Asken BM, Djukic NA, Lee S, Nilsson J, Brinkmalm A, Blennow K, Zetterberg H, Kramer JH, Casaletto KB

Sex-specific effects of microglial activation on Alzheimer's disease proteinopathy in older adults.

Brain : a journal of neurology

Casaletto KB, Nichols E, Aslanyan V, Simone SM, Rabin JS, LaJoie R, Brickman AM, Dams-O'Connor K, Palta P, Kumar RG, George KM, Satizabal CL, Schneider J, Pa J

POLYCYSTIC OVARY SYNDROME AND DIFFERENCES IN BRAIN HEALTH AT MID-LIFE: RESULTS FROM THE CARDIA COHORT.

Fertility and Sterility

Heather Gibson Huddleston, Eleni Jaswa, Kaitlin Casaletto, John Neuhaus, Kristine Yaffe

Assessment of cross-cultural measurement invariance of the NIH toolbox fluid cognition measures between Jamaicans and African-Americans.

Applied neuropsychology. Adult

Tennant IA, Hull DM, Fagan MA, Casaletto KB, Heaton RK, James Bateman C, Erickson KI, Forrester T, Boyne M

Temporal order of clinical and biomarker changes in familial frontotemporal dementia.

Nature medicine

Staffaroni AM, Quintana M, Wendelberger B, Heuer HW, Russell LL, Cobigo Y, Wolf A, Goh SM, Petrucelli L, Gendron TF, Heller C, Clark AL, Taylor JC, Wise A, Ong E, Forsberg L, Brushaber D, Rojas JC, VandeVrede L, Ljubenkov P, Kramer J, Casaletto KB, Appleby B, Bordelon Y, Botha H, Dickerson BC, Domoto-Reilly K, Fields JA, Foroud T, Gavrilova R, Geschwind D, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grossman M, Hall MGH, Hsiung GY, Huey ED, Irwin D, Jones DT, Kantarci K, Kaufer D, Knopman D, Kremers W, Lago AL, Lapid MI, Litvan I, Lucente D, Mackenzie IR, Mendez MF, Mester C, Miller BL, Onyike CU, Rademakers R, Ramanan VK, Ramos EM, Rao M, Rascovsky K, Rankin KP, Roberson ED, Savica R, Tartaglia MC, Weintraub S, Wong B, Cash DM, Bouzigues A, Swift IJ, Peakman G, Bocchetta M, Todd EG, Convery RS, Rowe JB, Borroni B, Galimberti D, Tiraboschi P, Masellis M, Finger E, van Swieten JC, Seelaar H, Jiskoot LC, Sorbi S, Butler CR, Graff C, Gerhard A, Langheinrich T, Laforce R, Sanchez-Valle R, de Mendonça A, Moreno F, Synofzik M, Vandenberghe R, Ducharme S, Le Ber I, Levin J, Danek A, Otto M, Pasquier F, Santana I, Kornak J, Boeve BF, Rosen HJ, Rohrer JD, Boxer AL, Frontotemporal Dementia Prevention Initiative (FPI) Investigators

Endophenotypic correlates of cognitive function in reproductive-age individuals with polycystic ovary syndrome.

F&S Reports

Huddleston HG, Casaletto KB, Jaswa EG, Rasgon NL, Maki PP, Cedars MI, Pasch L

Physical activity measurement in older adults: Wearables versus self-report.

Frontiers in digital health

VandeBunte A, Gontrum E, Goldberger L, Fonseca C, Djukic N, You M, Kramer JH, Casaletto KB

Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and cognitive decline.

Brain : a journal of neurology

Rabin JS, Nichols E, La Joie R, Casaletto KB, Palta P, Dams-O'Connor K, Kumar RG, George KM, Satizabal CL, Schneider JA, Pa J, Brickman AM

Effects of Sex, APOE4, and Lifestyle Activities on Cognitive Reserve in Older Adults.

Neurology

Pa J, Aslanyan V, Casaletto KB, RenterÃa MA, Harrati A, Tom SE, Armstrong N, Rajan K, Avila-Rieger J, Gu Y, Schupf N, Manly JJ, Brickman A, Zahodne L

Wearable Use in an Observational Study Among Older Adults: Adherence, Feasibility, and Effects of Clinicodemographic Factors.

Frontiers in digital health

Paolillo EW, Lee SY, VandeBunte A, Djukic N, Fonseca C, Kramer JH, Casaletto KB

Multimodal Biomarkers of Repetitive Head Impacts and Traumatic Encephalopathy Syndrome: A Clinico-Pathological Case Series.

Journal of neurotrauma

Asken B, Tanner JA, VandeVrede L, Casaletto KB, Staffaroni AM, Mundada N, Fonseca C, Iaccarino L, La Joie R, Tsuei T, Mladinov M, Grant H, Shankar R, Wang KKW, Xu H, Cobigo Y, Rosen H, Gardner RC, Perry DC, Miller BL, Spina S, Seeley WW, Kramer J, Grinberg LT, Rabinovici G

Plasma P-tau181 and P-tau217 in Patients With Traumatic Encephalopathy Syndrome With and Without Evidence of Alzheimer Disease Pathology.

Neurology

Asken BM, Tanner JA, VandeVrede L, Mantyh WG, Casaletto KB, Staffaroni AM, La Joie R, Iaccarino L, Soleimani-Meigooni D, Rojas JC, Gardner RC, Miller BL, Grinberg LT, Boxer AL, Kramer JH, Rabinovici GD

Roles of physical activity and diet in cognitive aging: is more better?

The Clinical neuropsychologist

E Escher C, Asken BM, VandeBunte A, Fonseca C, You M, Kramer JH, Casaletto KB

Neuroanatomical correlations of visuospatial processing in primary progressive aphasia.

Brain Communications

Tee BL, Watson Pereira C, Lukic S, Bajorek LP, Allen IE, Miller ZA, Casaletto KB, Miller BL, Gorno-Tempini ML

Author Correction: Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans.

Scientific reports

Elahi FM, Harvey D, Altendahl M, Brathaban N, Fernandes N, Casaletto KB, Staffaroni AM, Maillard P, Hinman JD, Miller BL, DeCarli C, Kramer JH, Goetzl EJ

Late-life physical activity relates to brain tissue synaptic integrity markers in older adults.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Casaletto K, Ramos-Miguel A, VandeBunte A, Memel M, Buchman A, Bennett D, Honer W

Defining physical activity: A comparison of actigraphy monitoring and self-report measures.

Alzheimer's & Dementia

Anna M. VandeBunte, Nina Djukic, Michelle You, Corrina Fonseca, Joel H Kramer, Kaitlin B Casaletto

Distinct patters of associations between cognitive performance and Alzheimer’s disease biomarkers in a multinational cohort of clinically normal older adults.

Alzheimer's & Dementia

Elena Tsoy, Anna Brugulat-Serrat, Lawren Vandevrede, Sabrina J Erlhoff, Kaitlin B Casaletto, Katherine P Rankin, Joel H Kramer, Kate L Possin, EPAD Consortium

Sex differences in the behavioral variant of frontotemporal dementia: A new window to executive and behavioral reserve.

Alzheimer's & Dementia

Ignacio Illán-Gala, Kaitlin B. Casaletto, Sergi Borrego-Écija, Eider M Arenaza-Urquijo, Amy Wolf, Yann Cobigo, Sheng-Yang Matthew Goh, Adam M. Staffaroni, Daniel Alcolea, Juan Fortea, Rafael Blesa, Jordi Clarimon, M. Florencia Iulita, Anna Brugulat-Serrat, Albert Lladó, Lea T. Grinberg, Kate L Possin, Katherine P Rankin, Joel H Kramer, Gil D. Rabinovici, Adam L. Boxer, William W. Seeley, Virginia Sturm, Maria Luisa Gorno Tempini, Bruce L. Miller, Raquel Sanchez-Valle, David C. Perry, Alberto Lleó, Howard J. Rosen

Microglial correlates of late life physical activity: Relationship with synaptic and cognitive aging in older adults.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Casaletto KB, Lindbergh CA, VandeBunte A, Neuhaus J, Schneider JA, Buchman AS, Honer WG, Bennett DA

Inter-Batch Reliability of Blood-Based Cytokine and Chemokine Measurements in Community-Dwelling Older Adults: A Cross-Sectional Study.

The journals of gerontology. Series A, Biological sciences and medical sciences

Lindbergh CA, Asken BM, Casaletto KB, Elahi FM, Goldberger LA, Fonseca C, You M, Apple AC, Staffaroni AM, Fitch R, Rivera Contreras W, Wang P, Karydas A, Kramer JH, Hillblom Aging Network

Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans.

Scientific reports

Elahi FM, Harvey D, Altendahl M, Brathaban N, Fernandes N, Casaletto KB, Staffaroni AM, Maillard P, Hinman JD, Miller BL, DeCarli C, Kramer JH, Goetzl EJ

Tripartite Relationship Among Synaptic, Amyloid, and Tau Proteins: An In Vivo and Postmortem Study.

Neurology

Casaletto KB, Zetterberg H, Blennow K, Brinkmalm A, Honer W, Schneider JA, Bennett DA, Djukic N, You M, Weiner-Light S, Fonseca C, Miller BL, Kramer J

Lower White Matter Volume and Worse Executive Functioning Reflected in Higher Levels of Plasma GFAP among Older Adults with and Without Cognitive Impairment.

Journal of the International Neuropsychological Society : JINS

Asken BM, VandeVrede L, Rojas JC, Fonseca C, Staffaroni AM, Elahi FM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Boxer AL, Miller BL, Rosen HJ, Kramer JH, Casaletto KB

Multimodal neuroimaging of sex differences in cognitively impaired patients on the Alzheimer's continuum: greater tau-PET retention in females.

Neurobiology of aging

Edwards L, La Joie R, Iaccarino L, Strom A, Baker SL, Casaletto KB, Cobigo Y, Grant H, Kim M, Kramer JH, Mellinger TJ, Pham J, Possin KL, Rosen HJ, Soleimani-Meigooni DN, Wolf A, Miller BL, Rabinovici GD

APOE moderates the effect of hippocampal blood flow on memory pattern separation in clinically normal older adults.

Hippocampus

Memel M, Staffaroni AM, Cobigo Y, Casaletto KB, Fonseca C, Bettcher BM, Yassa MA, Elahi FM, Wolf A, Rosen HJ, Kramer JH

The Rapid Naming Test: Development and initial validation in typically aging adults.

The Clinical neuropsychologist

Stiver J, Staffaroni AM, Walters SM, You MY, Casaletto KB, Erlhoff SJ, Possin KL, Lukic S, La Joie R, Rabinovici GD, Zimmerman ME, Gorno-Tempini ML, Kramer JH

Uniform data set language measures for bvFTD and PPA diagnosis and monitoring.

Alzheimer's & dementia (Amsterdam, Netherlands)

Staffaroni AM, Weintraub S, Rascovsky K, Rankin KP, Taylor J, Fields JA, Casaletto KB, Hillis AE, Lukic S, Gorno-Tempini ML, Heuer H, Teylan MA, Kukull WA, Miller BL, Boeve BF, Rosen HJ, Boxer AL, Kramer JH

Sex differences in the behavioral variant of frontotemporal dementia: A new window to executive and behavioral reserve.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Illán-Gala I, Casaletto KB, Borrego-Écija S, Arenaza-Urquijo EM, Wolf A, Cobigo Y, Goh SYM, Staffaroni AM, Alcolea D, Fortea J, Blesa R, Clarimon J, Iulita MF, Brugulat-Serrat A, Lladó A, Grinberg LT, Possin K, Rankin KP, Kramer JH, Rabinovici GD, Boxer A, Seeley WW, Sturm VE, Gorno-Tempini ML, Miller BL, Sánchez-Valle R, Perry DC, Lleó A, Rosen HJ

Mild Motor Signs Matter in Typical Brain Aging: The Value of the UPDRS Score Within a Functionally Intact Cohort of Older Adults.

Frontiers in aging neuroscience

Zitser J, Casaletto KB, Staffaroni AM, Sexton C, Weiner-Light S, Wolf A, Brown JA, Miller BL, Kramer JH

Association of remote mild traumatic brain injury with cortical amyloid burden in clinically normal older adults.

Brain imaging and behavior

Asken BM, Mantyh WG, La Joie R, Strom A, Casaletto KB, Staffaroni AM, Apple AC, Lindbergh CA, Iaccarino L, You M, Grant H, Fonseca C, Windon C, Younes K, Tanner J, Rabinovici GD, Kramer JH, Gardner RC

Plasma Glial Fibrillary Acidic Protein Levels Differ Along the Spectra of Amyloid Burden and Clinical Disease Stage.

Journal of Alzheimer's disease : JAD

Asken BM, Elahi FM, La Joie R, Strom A, Staffaroni AM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Karydas A, Wang P, Rojas JC, Boxer AL, Miller BL, Rabinovici GD, Kramer JH, Casaletto KB

Effect of sex and physical and cognitive activities on cognitive reserve in a cohort of ethnically diverse, community-dwelling older adults.

Alzheimer's & Dementia

Judy Pa, Vahan Aslayan, Kaitlin B Casaletto, Miguel Arce Rentería, Amal Harrati, Sarah E Tom, Nicole Armstrong, Kumar B Rajan, Yian Gu, Jennifer J Manly, Adam M Brickman, Laura B Zahodne

Medial temporal contributions to learning, retrieval, and accuracy monitoring in verbal memory.

Alzheimer's & Dementia

Molly B. Memel, Kaitlin B Casaletto, Joel H. Kramer

Plasma biomarkers of inflammation reflect disease state in autosomal dominant forms of familial frontotemporal dementia.

Alzheimer's & Dementia

Peter A. Ljubenkov, Adam M. Staffaroni, Kaitlin B. Casaletto, Julio C. Rojas, Lawren Vandevrede, Hilary W. Heuer, Fanny M. Elahi, Danielle Brushaber, Tatiana M. Foroud, Leah K. Forsberg, Anna M. Karydas, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer, Joel H. Kramer, ARTFL and LEFFTDS Consortium Investigators

The evolution of brain atrophy across the disease spectrum of familial frontotemporal dementia.

Alzheimer's & Dementia

Adam M. Staffaroni, Sheng-Yang Matthew Goh, Yann Cobigo, Elise Ong, Suzee E. Lee, Kaitlin B. Casaletto, Amy Wolf, Leah K. Forsberg, Nupur Ghoshal, Neill R. Graff-Radford, Murray Grossman, Hilary W. Heuer, Ging-Yuek Robin Hsiung, Kejal Kantarci, David S. Knopman, Walter K. Kremers, Ian R. Mackenzie, Bruce L. Miller, Otto Pedraza, Katya Rascovsky, Carmela Tartaglia, Zbigniew Wszolek, Joel H. Kramer, John Kornak, Bradley F. Boeve, Adam L. Boxer, Howard J. Rosen

Development and validation of the Uniform Data Set (v3.0) executive function composite score (UDS3-EF).

Alzheimer's & dementia : the journal of the Alzheimer's Association

Staffaroni AM, Asken BM, Casaletto KB, Fonseca C, You M, Rosen HJ, Boxer AL, Elahi FM, Kornak J, Mungas D, Kramer JH

Worth the Wait: Delayed Recall after 1 Week Predicts Cognitive and Medial Temporal Lobe Trajectories in Older Adults.

Journal of the International Neuropsychological Society : JINS

Lindbergh CA, Walker N, La Joie R, Weiner-Light S, Staffaroni AM, Casaletto KB, Elahi F, Walters SM, You M, Cotter D, Asken B, Apple AC, Tsoy E, Neuhaus J, Fonseca C, Wolf A, Cobigo Y, Rosen H, Kramer JH

Sex-related differences in the relationship between ß-amyloid and cognitive trajectories in older adults.

Neuropsychology

Lindbergh CA, Casaletto KB, Staffaroni AM, La Joie R, Iaccarino L, Edwards L, Tsoy E, Elahi F, Walters SM, Cotter D, You M, Apple AC, Asken B, Neuhaus J, Rexach JE, Wojta KJ, Rabinovici G, Kramer JH

Rates of Brain Atrophy Across Disease Stages in Familial Frontotemporal Dementia Associated With MAPT, GRN, and C9orf72 Pathogenic Variants.

JAMA network open

Staffaroni AM, Goh SM, Cobigo Y, Ong E, Lee SE, Casaletto KB, Wolf A, Forsberg LK, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Hsiung GR, Kantarci K, Knopman DS, Kremers WK, Mackenzie IR, Miller BL, Pedraza O, Rascovsky K, Tartaglia MC, Wszolek ZK, Kramer JH, Kornak J, Boeve BF, Boxer AL, Rosen HJ

Baseline neuropsychological profiles in prion disease predict survival time.

Annals of clinical and translational neurology

Sundaram SE, Staffaroni AM, Walker NC, Casaletto KB, Casey M, Golubjatnikov A, Metcalf S, O'Leary K, Wong K, Benisano K, Forner S, Gonzalez Catalan M, Allen IE, Rosen HJ, Kramer JH, Geschwind MD

Systemic Tumor Necrosis Factor-Alpha Trajectories Relate to Brain Health in Typically Aging Older Adults.

The journals of gerontology. Series A, Biological sciences and medical sciences

Lindbergh CA, Casaletto KB, Staffaroni AM, Elahi F, Walters SM, You M, Neuhaus J, Rivera Contreras W, Wang P, Karydas A, Brown J, Wolf A, Rosen H, Cobigo Y, Kramer JH

Blood factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain.

Science (New York, N.Y.)

Horowitz AM, Fan X, Bieri G, Smith LK, Sanchez-Diaz CI, Schroer AB, Gontier G, Casaletto KB, Kramer JH, Williams KE, Villeda SA

REM sleep is associated with white matter integrity in cognitively healthy, older adults.

PloS one

Altendahl M, Cotter DL, Staffaroni AM, Wolf A, Mumford P, Cobigo Y, Casaletto K, Elahi F, Ruoff L, Javed S, Bettcher BM, Fox E, You M, Saloner R, Neylan TC, Kramer JH, Walsh CM

Aging and Positive Mood: Longitudinal Neurobiological and Cognitive Correlates.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Cotter DL, Walters SM, Fonseca C, Wolf A, Cobigo Y, Fox EC, You MY, Altendahl M, Djukic N, Staffaroni AM, Elahi FM, Kramer JH, Casaletto KB

Sexual dimorphism of physical activity on cognitive aging: Role of immune functioning.

Brain, behavior, and immunity

Casaletto KB, Lindbergh C, Memel M, Staffaroni A, Elahi F, Weiner-Light S, You M, Fonseca C, Karydas A, Jacobs E, Dubal DB, Yaffe K, Kramer JH

Get Moving! Increases in Physical Activity Are Associated With Increasing Functional Connectivity Trajectories in Typically Aging Adults.

Frontiers in aging neuroscience

Dorsman KA, Weiner-Light S, Staffaroni AM, Brown JA, Wolf A, Cobigo Y, Walters S, Kramer JH, Casaletto KB

Bilateral basal ganglia infarcts presenting as rapid onset cognitive and behavioral disturbance.

Neurocase

Hellmuth J, Casaletto K, Cuneo R, Possin KL, Dillon W, Geschwind MD

Plasma biomarkers of astrocytic and neuronal dysfunction in early- and late-onset Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Elahi FM, Casaletto KB, La Joie R, Walters SM, Harvey D, Wolf A, Edwards L, Rivera-Contreras W, Karydas A, Cobigo Y, Rosen HJ, DeCarli C, Miller BL, Rabinovici GD, Kramer JH

Differential cognitive substrates of verbal episodic memory performance in semantic variant primary progressive aphasia and Alzheimer's disease.

Journal of neuropsychology

DeVaughn S, Casaletto KB, Staffaroni AM, Wolf AA, Marx G, Kramer JH

Active lifestyles moderate clinical outcomes in autosomal dominant frontotemporal degeneration.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Casaletto KB, Staffaroni AM, Wolf A, Appleby B, Brushaber D, Coppola G, Dickerson B, Domoto-Reilly K, Elahi FM, Fields J, Fong JC, Forsberg L, Ghoshal N, Graff-Radford N, Grossman M, Heuer HW, Hsiung GY, Huey ED, Irwin D, Kantarci K, Kaufer D, Kerwin D, Knopman D, Kornak J, Kramer JH, Litvan I, Mackenzie IR, Mendez M, Miller B, Rademakers R, Ramos EM, Rascovsky K, Roberson ED, Syrjanen JA, Tartaglia MC, Weintraub S, Boeve B, Boxer AL, Rosen H, Yaffe K

Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Staffaroni AM, Bajorek L, Casaletto KB, Cobigo Y, Goh SM, Wolf A, Heuer HW, Elahi FM, Ljubenkov PA, Dever R, Kornak J, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dheel C, Dickerson BC, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fields JA, Fishman A, Fong J, Foroud T, Forsberg LK, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Hsiung GY, Huey ED, Irwin DJ, Jones DT, Jones L, Kantarci K, Karydas A, Kaufer DI, Kerwin DR, Knopman DS, Kraft R, Kremers WK, Kukull WA, Litvan I, Lucente D, Lungu C, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley E, Mendez MF, Miller BL, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wang P, Wong B, Wszolek Z, Boxer AL, Boeve BF, Kramer JH, Rosen HJ

Late-Life Physical and Cognitive Activities Independently Contribute to Brain and Cognitive Resilience.

Journal of Alzheimer's disease : JAD

Casaletto KB, Rentería MA, Pa J, Tom SE, Harrati A, Armstrong NM, Rajan KB, Mungas D, Walters S, Kramer J, Zahodne LB

Plasma Glial Fibrillary Acidic Protein Levels Differ Along the Spectra of Amyloid Burden and Clinical Disease Stage.

Journal of Alzheimer's disease : JAD

Asken BM, Elahi FM, La Joie R, Strom A, Staffaroni AM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Karydas A, Wang P, Rojas JC, Boxer AL, Miller BL, Rabinovici GD, Kramer JH, Casaletto KB

DYNAMIC, BIDIRECTIONAL LONGITUDINAL RELATIONSHIP BETWEEN LEISURE ACTIVITY ENGAGEMENT AND COGNITIVE PERFORMANCE.

Innovation in aging

Nicole Armstrong, Sarah Tom, Miguel Arce Renteria, Kaitlin Casaletto, Jennifer Weuve, Eleanor M Simonsick, Jennifer Manly, Laura B Zahodne

PHYSICAL VERSUS COGNITIVE ACTIVITY FOR SUCCESSFUL AGING: BRAIN MAINTENANCE OR COGNITIVE RESERVE?.

Innovation in aging

Kaitlin Casaletto, Kaitlin B Casaletto, Judy Pa, Sarah Tom, Miguel Arce-Renteria, Amal Harrati, Nicole Armstrong, Laura Zahodne

C-24 Longitudinal Trajectories of Working Memory Performance in Typically Aging Older Adults.

Archives of Clinical Neuropsychology

M Gonzalez Catalan, C Lindbergh, A Staffaroni, S Walters, K Casaletto, N Walker, J Kramer

Robust normative standards for the California Verbal Learning Test (CVLT) ages 60-89: A tool for early detection of memory impairment.

The Clinical neuropsychologist

Kramer AO, Casaletto KB, Umlauf A, Staffaroni AM, Fox E, You M, Kramer JH

RELIABLE CHANGE IN OLDER ADULTS ON A BRIEF COMPUTERIZED COGNITIVE TEST: COMPARISONS WITH THE MOCA AND ASSOCIATIONS WITH AMYLOID BURDEN.

Alzheimer's & Dementia

Elena Tsoy, Sabrina Erlhoff, Suchanan Kanjanapong, Kaitlin B. Casaletto, Katherine Rankin, Joel H. Kramer, Katherine L. Possin

STEP COUNT AND PSYCHOLOGICAL HEALTH IN OLDER ADULTS.

Alzheimer's & Dementia

Sophia A. Weiner-Light, Samantha Walters, Nina Djukic, Michelle You, Devyn Cotter, Marie Altendahl, Fanny Elahi, Adam M. Staffaroni, Cutter A. Lindbergh, Joel H. Kramer, Kaitlin B. Casaletto

An Opioid-Related Amnestic Syndrome With Persistent Effects on Hippocampal Structure and Function.

The Journal of neuropsychiatry and clinical neurosciences

Butler PM, Barash JA, Casaletto KB, Cotter DL, La Joie R, Geschwind MD, Rosen HJ, Kramer JH, Miller BL

National Institutes of Health Toolbox Emotion Battery: Application of Summary Scores to Adults With Spinal Cord Injury, Traumatic Brain Injury, and Stroke.

Archives of physical medicine and rehabilitation

Babakhanyan I, Carlozzi NE, McKenna BS, Casaletto KB, Heinemann AW, Heaton RK

A longitudinal characterization of perfusion in the aging brain and associations with cognition and neural structure.

Human brain mapping

Staffaroni AM, Cobigo Y, Elahi FM, Casaletto KB, Walters SM, Wolf A, Lindbergh CA, Rosen HJ, Kramer JH

White Matter Correlates of Cognitive Performance on the UCSF Brain Health Assessment.

Journal of the International Neuropsychological Society : JINS

Alioto AG, Mumford P, Wolf A, Casaletto KB, Erlhoff S, Moskowitz T, Kramer JH, Rankin KP, Possin KL

Increases in a Pro-inflammatory Chemokine, MCP-1, Are Related to Decreases in Memory Over Time.

Frontiers in aging neuroscience

Bettcher BM, Neuhaus J, Wynn MJ, Elahi FM, Casaletto KB, Saloner R, Fitch R, Karydas A, Kramer JH

Cognitive aging is not created equally: differentiating unique cognitive phenotypes in "normal" adults.

Neurobiology of aging

Casaletto KB, Elahi FM, Staffaroni AM, Walters S, Contreras WR, Wolf A, Dubal D, Miller B, Yaffe K, Kramer JH

"Liquid Biopsy" of White Matter Hyperintensity in Functionally Normal Elders.

Frontiers in aging neuroscience

Elahi FM, Casaletto KB, Altendahl M, Staffaroni AM, Fletcher E, Filshtein TJ, Glymour MM, Miller BL, Hinman JD, DeCarli C, Goetzl EJ, Kramer JH

ENDOTHELIAL-DERIVED EXOSOME BIOMARKERS SUGGEST ACTIVATION OF INNATE IMMUNITY IN SUBCLINICAL CEREBROVASCULAR DISEASE.

Alzheimer's & Dementia

Fanny Elahi, Marie Altendahl, Teresa J. Filshtein, Kaitlin Casaletto, Adam M. Staffaroni, Wilfredo Rivera Contreras, Anna M. Karydas, Yann Cobigo, Evan Fletcher, Baljeet Singh, Oliver Martinez, Howard J. Rosen, Jason Hinman, Katerina Akassoglou, Maria Glymour, Charlie S. DeCarli, Edward J. Goetzl, Joel H. Kramer

THE NIH-EXAMINER IS SENSITIVE TO COGNITIVE CHANGES IN ASYMPTOMATIC AND MILDLY SYMPTOMATIC FAMILIAL FRONTOTEMPORAL DEMENTIA.

Alzheimer's & Dementia

Adam M. Staffaroni, Lynn Bajorek, Peter Ljubenkov, Kaitlin Casaletto, Fanny Elahi, Katya Rascovsky, Bradley F. Boeve, Adam L. Boxer, Jessica Bove, Danielle Brushaber, Giovanni Coppola, Christina Dheel, Brad C. Dickerson, Julie A. Fields, Jamie Fong, Leah K. Forsberg, Ralitza H. Gavrilova, Debra Gearhart, Nupur Ghoshal, Jill Goldman, Jonathan Graff Radford, Neill R. Graff-Radford, Murray Grossman, Dana Haley, Hilary W. Heuer, John Hsiao, Ging-Yuek Robin Hsiung, Edward Huey, David J. Irwin, David T. Jones, Lynne Jones, Kejal Kantarci, Anna M. Karydas, David S. Knopman, John Kornak, Walter K. Kremers, Walter A. Kukull, Maria I. Lapid, Diane Lucente, Ian R. Mackenzie, Masood Manoochehri, Bruce L. Miller, Madeline Potter, Rosa Rademakers, Katherine Rankin, Margaret Sutherland, Jeremy Syrjanen, Joanne Taylor, Sandra Weintraub, Bonnie Wong, Zbigniew Wszolek, Howard J. Rosen, Joel H. Kramer, ARTFL/LEFFTDS Consortium

Perceived Stress is Associated with Accelerated Monocyte/Macrophage Aging Trajectories in Clinically Normal Adults.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Casaletto KB, Staffaroni AM, Elahi F, Fox E, Crittenden PA, You M, Neuhaus J, Glymour M, Bettcher BM, Yaffe K, Kramer JH

A comparison of biofluid cytokine markers across platform technologies: Correspondence or divergence?

Cytokine

Casaletto KB, Elahi FE, Fitch R, Walters S, Fox E, Staffaroni AM, Bettcher B, Zetterberg H, Karydas A, Rojas JC, Boxer AL, Kramer JH

Telomere attrition is associated with declines in medial temporal lobe volume and white matter microstructure in functionally independent older adults.

Neurobiology of aging

Staffaroni AM, Tosun D, Lin J, Elahi FM, Casaletto KB, Wynn MJ, Patel N, Neuhaus J, Walters SM, Epel ES, Blackburn EH, Kramer JH

Biomarkers of Cerebral Small Vessel Endotheliopathy (S48.005).

Neurology

Fanny Elahi, Marie Altendahl, Adam Staffaroni, Kaitlin Casaletto, Pauline Maillard, John Neuhaus, Jason Hinman, Charles DeCarli, Edward Goetzl, Joel Kramer

Plasma Biomarkers in Early Neurodegenerative Disease Stages (P3.027).

Neurology

Fanny Elahi, Kaitlin Casaletto, Adam Staffaroni, John Neuhaus, Yann Cobigo, Emily Fox, Samantha Walters, Marie Altendahl, Ryan Fitch, Anna Karydas, Jason Hinman, Charles DeCarli, Adam Boxer, Gil Rabinovici, Howard Rosen, Bruce Miller, Joel Kramer

National Institutes of Health Toolbox Emotion Battery for English- and Spanish-speaking adults: normative data and factor-based summary scores.

Patient related outcome measures

Babakhanyan I, McKenna BS, Casaletto KB, Nowinski CJ, Heaton RK

The Longitudinal Trajectory of Default Mode Network Connectivity in Healthy Older Adults Varies As a Function of Age and Is Associated with Changes in Episodic Memory and Processing Speed.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Staffaroni AM, Brown JA, Casaletto KB, Elahi FM, Deng J, Neuhaus J, Cobigo Y, Mumford PS, Walters S, Saloner R, Karydas A, Coppola G, Rosen HJ, Miller BL, Seeley WW, Kramer JH

Cerebrospinal Fluid and Plasma Levels of Inflammation Differentially Relate to CNS Markers of Alzheimer's Disease Pathology and Neuronal Damage.

Journal of Alzheimer's disease : JAD

Bettcher BM, Johnson SC, Fitch R, Casaletto KB, Heffernan KS, Asthana S, Zetterberg H, Blennow K, Carlsson CM, Neuhaus J, Bendlin BB, Kramer JH

M. avium Complex and Other Nontuberculous Mycobacteria and HIV.

Jeffrey D. Jenks, Constance A. Benson, Awatef Allouch, Gianfranco Pancino, Nicholas Francella, Sarah T. Elliot, Ronald G. Collman, Jeffrey E. Korte, D. Cristina Stefan, Susan E. Krown, Annesa Flentje, James L. Sorensen, Shashi Kapadia, Marshall J. Glesby, David J. Moore, Jessica L. Montoya, Kaitlin B. Casaletto, J. Hampton Atkinson, Nathalie C. Zeitouni, Bethany Lema, Nicole Fischer, Adam Grundhoff, Xiaojiang Gao, Arman Bashirova, Mary Carrington, Alexandra M. Ortiz, Jason M. Brenchley, Rupali J. Limaye, Susan G. Sherman, Louis M. Weiss, Oren S. Weiss, Jacob G. Ludington, Honorine D. Ward, Andrew M. L. Lever, Mariangela Cavarelli, Gabriella Scarlatti, Katherine Semrau, Grace M. Aldrovandi, Barbara L. Shacklett, Ivona Pandrea, Cara C. Wilson, Cristian Apetrei, Mark N. Polizzotto, Thomas S. Uldrick, Robert Yarchoan, Crystal Fuller Lewis, Natalie D. Crawford, Caroline Goujon

Medication Adherence and HIV-Associated Neurocognitive Disorders (HAND).

Encyclopedia of AIDS

David J. Moore, Jessica L. Montoya, Kaitlin B. Casaletto, J. Hampton Atkinson

Everyday Multitasking Abilities in Older HIV+ Adults: Neurobehavioral Correlates and the Mediating Role of Metacognition.

Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

Fazeli PL, Casaletto KB, Woods SP, Umlauf A, Scott JC, Moore DJ

Construct validity of the NIH Toolbox Cognition Battery in individuals with stroke.

Rehabilitation psychology

Carlozzi NE, Tulsky DS, Wolf TJ, Goodnight S, Heaton RK, Casaletto KB, Wong AWK, Baum CM, Gershon RC, Heinemann AW

Uncorrected versus demographically-corrected scores on the NIH Toolbox Cognition Battery in persons with traumatic brain injury and stroke.

Rehabilitation psychology

Nitsch KP, Casaletto KB, Carlozzi NE, Tulsky DS, Heinemann AW, Heaton RK

Neuropsychological Assessment: Past and Future.

Journal of the International Neuropsychological Society : JINS

Casaletto KB, Heaton RK

Neurogranin, a synaptic protein, is associated with memory independent of Alzheimer biomarkers.

Neurology

Casaletto KB, Elahi FM, Bettcher BM, Neuhaus J, Bendlin BB, Asthana S, Johnson SC, Yaffe K, Carlsson C, Blennow K, Zetterberg H, Kramer JH

Performance on a 1-week delayed recall task is associated with medial temporal lobe structures in neurologically normal older adults.

The Clinical neuropsychologist

Saloner R, Casaletto KB, Marx G, Dutt S, Vanden Bussche AB, You M, Fox E, Stiver J, Kramer JH

Validation of the NIH Toolbox in Individuals with Neurologic Disorders.

Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

Carlozzi NE, Goodnight S, Casaletto KB, Goldsmith A, Heaton RK, Wong AWK, Baum CM, Gershon R, Heinemann AW, Tulsky DS

CSF AND PLASMA LEVELS OF INFLAMMATION DIFFERENTIALLY RELATE TO CNS MARKERS OF ALZHEIMER'S DISEASE PATHOLOGY AND NEURONAL DAMAGE.

Alzheimer's & Dementia

Brianne M. Bettcher, Sterling C. Johnson, Ryan Fitch, Kaitlin Casaletto, Kate S. Heffernan, Sanjay Asthana, Henrik Zetterberg, Kaj Blennow, Cynthia M. Carlsson, John Neuhaus, Barbara B. Bendlin, Joel H. Kramer

The role of executive functioning in memory performance in pediatric focal epilepsy.

Epilepsia

Sepeta LN, Casaletto KB, Terwilliger V, Facella-Ervolini J, Sady M, Mayo J, Gaillard WD, Berl MM

Performance of Hispanics and Non-Hispanic Whites on the NIH Toolbox Cognition Battery: the roles of ethnicity and language backgrounds.

The Clinical neuropsychologist

Flores I, Casaletto KB, Marquine MJ, Umlauf A, Moore DJ, Mungas D, Gershon RC, Beaumont JL, Heaton RK

Medication Adherence and HIV-Associated Neurocognitive Disorders (HAND).

Encyclopedia of AIDS

David J. Moore, Jessica L. Montoya, Kaitlin B. Casaletto, J. Hampton Atkinson

Real-World Impact of HIV-Associated Neurocognitive Impairment.

Changes in the Brain

Kaitlin Blackstone Casaletto, Erica Weber, Jennifer E. Iudicello, Steven Paul Woods

Retinal thinning is uniquely associated with medial temporal lobe atrophy in neurologically normal older adults.

Neurobiology of aging

Casaletto KB, Ward ME, Baker NS, Bettcher BM, Gelfand JM, Li Y, Chen R, Dutt S, Miller B, Kramer JH, Green AJ

Evaluating the accuracy of self-report for the diagnosis of HIV-associated neurocognitive disorder (HAND): defining "symptomatic" versus "asymptomatic" HAND.

Journal of neurovirology

Obermeit LC, Beltran J, Casaletto KB, Franklin DR, Letendre S, Ellis R, Fennema-Notestine C, Vaida F, Collier AC, Marra CM, Clifford D, Gelman B, Sacktor N, Morgello S, Simpson D, McCutchan JA, Grant I, Heaton RK

Pill Burden Influences the Association Between Time-Based Prospective Memory and Antiretroviral Therapy Adherence in Younger But Not Older HIV-Infected Adults.

The Journal of the Association of Nurses in AIDS Care : JANAC

Sheppard DP, Weber E, Casaletto KB, Avci G, Woods SP

Demographically Corrected Normative Standards for the Spanish Language Version of the NIH Toolbox Cognition Battery.

Journal of the International Neuropsychological Society : JINS

Casaletto KB, Umlauf A, Marquine M, Beaumont JL, Mungas D, Gershon R, Slotkin J, Akshoomoff N, Heaton RK

Predictors of psychotropic medication adherence among HIV+ individuals living with bipolar disorder.

International journal of psychiatry in medicine

Casaletto KB, Kwan S, Montoya JL, Obermeit LC, Gouaux B, Poquette A, Heaton RK, Atkinson JH, Moore DJ

Visualisation of future task performance improves naturalistic prospective memory for some younger adults living with HIV disease.

Neuropsychological rehabilitation

Faytell MP, Doyle KL, Naar-King S, Outlaw AY, Nichols SL, Casaletto KB, Woods SP

Demographically Corrected Normative Standards for the English Version of the NIH Toolbox Cognition Battery.

Journal of the International Neuropsychological Society : JINS

Casaletto KB, Umlauf A, Beaumont J, Gershon R, Slotkin J, Akshoomoff N, Heaton RK

Antiretroviral Non-Adherence is Associated With a Retrieval Profile of Deficits in Verbal Episodic Memory.

The Clinical neuropsychologist

Obermeit LC, Morgan EE, Casaletto KB, Grant I, Woods SP

Individualized texting for adherence building (iTAB): improving antiretroviral dose timing among HIV-infected persons with co-occurring bipolar disorder.

AIDS and behavior

Moore DJ, Poquette A, Casaletto KB, Gouaux B, Montoya JL, Posada C, Rooney AS, Badiee J, Deutsch R, Letendre SL, Depp CA, Grant I, Atkinson JH

Reply to Haddow et al.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Heaton RK, Franklin DR, Deutsch R, Letendre SL, Ellis RJ, Casaletto K, Marquine MJ, Woods SP, Vaida F, Atkinson JH, Marcotte TD, McCutchan JA, Collier AC, Marra CM, Clifford DB, Gelman BB, Sacktor N, Morgello S, Simpson DM, Abramson I, Gamst A, Fennema-Notestine C, Smith DM, Grant I

Self-predictions of prospective memory in HIV-associated neurocognitive disorders: evidence of a metamemory deficit.

Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

Casaletto KB, Doyle KL, Weber E, Woods SP

Neurocognitive change in the era of HIV combination antiretroviral therapy: the longitudinal CHARTER study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Heaton RK, Franklin DR, Deutsch R, Letendre S, Ellis RJ, Casaletto K, Marquine MJ, Woods SP, Vaida F, Atkinson JH, Marcotte TD, McCutchan JA, Collier AC, Marra CM, Clifford DB, Gelman BB, Sacktor N, Morgello S, Simpson DM, Abramson I, Gamst AC, Fennema-Notestine C, Smith DM, Grant I

The Wide Range Achievement Test-4 Reading subtest "holds" in HIV-infected individuals.

Journal of clinical and experimental neuropsychology

Casaletto KB, Cattie J, Franklin DR, Moore DJ, Woods SP, Grant I, Heaton RK

Depression and executive dysfunction contribute to a metamemory deficit among individuals with methamphetamine use disorders.

Addictive behaviors

Casaletto KB, Obermeit L, Morgan EE, Weber E, Franklin DR, Grant I, Woods SP

Allowing brief delays in responding improves event-based prospective memory for young adults living with HIV disease.

Journal of clinical and experimental neuropsychology

Loft S, Doyle KL, Naar-King S, Outlaw AY, Nichols SL, Weber E, Casaletto KB, Woods SP

Reliability and validity of composite scores from the NIH Toolbox Cognition Battery in adults.

Journal of the International Neuropsychological Society : JINS

Heaton RK, Akshoomoff N, Tulsky D, Mungas D, Weintraub S, Dikmen S, Beaumont J, Casaletto KB, Conway K, Slotkin J, Gershon R

Shallow encoding and forgetting are associated with dependence in instrumental activities of daily living among older adults living with HIV infection.

Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

Fazeli PL, Doyle KL, Scott JC, Iudicello JE, Casaletto KB, Weber E, Moore DJ, Morgan EE, Grant I, Woods SP