Adam Staffaroni, PhD

Associate Professor

Dr. Staffaroni is a clinical neuropsychologist and Associate Professor at the UCSF Memory and Aging Center. His research focuses on improving early detection, prognosis, and monitoring of neurodegenerative diseases through a combination of clinical tests, neuroimaging, and blood-based biomarkers. He leads studies of remote digital data collection in frontotemporal dementia using smartphone assessments and sensor technologies.

Publications: 

Linking Type and Extent of Head Trauma to Cavum Septum Pellucidum in Older Adults With and Without Alzheimer Disease and Related Dementias.

Neurology

Asken BM, Tanner JA, Vandevrede L, Apple A, Chapleau M, Gaynor LS, Lane-Donovan C, Lenio S, Yadollahikhales G, Lee S, Gontrum E, Knudtson M, Iaccarino L, La Joie R, Cobigo Y, Staffaroni AM, Casaletto KB, Gardner RC, Grinberg LT, Gorno-Tempini ML, Rosen HJ, Seeley WW, Miller BL, Kramer J, Rabinovici GD

Cognitive function influences cognitive-motor interference during dual task walking in multiple sclerosis.

Multiple sclerosis and related disorders

Hsu WY, Block VJ, Wijangco J, Henderson K, Nylander A, Koshal K, Poole S, Possin KL, Staffaroni AM, Bove RM

Building a normative sample for smartphone-based measures of cognition and motor functioning: Study design and initial feasibility findings.

Alzheimer's & Dementia

Sreya Dhanam, Adam M. Staffaroni, Jack C Taylor, Mark E. Sanderson-Cimino, Amy B. Wise, Annie L Clark, Hilary W. Heuer, Winnie Kwang, Joel H. Kramer, Brad F. Boeve, Howard J. Rosen, Michael S. W. Weiner, Rachel L Nosheny, Adam L. Boxer

Clinical value of CSF TMEM106B in familial and sporadic frontotemporal lobar degeneration.

Alzheimer's & Dementia

Julio C. Rojas, Yann Cobigo, Amy B. Wise, Jingyao Li, Joseph Loureiro, Katie Worringer, Hilary W. Heuer, Peter A. Ljubenkov, Lawren VandeVrede, Adam M. Staffaroni, Argentina Lario Lago, Eliana Marisa Ramos, Mercedes Prudencio, Jordan M. Marks, Casey N. Cook, Jolien Pernieel, Rosa Rademakers, Leonard Petrucelli, Brad F. Boeve, Howard J. Rosen, Adam L. Boxer, ALLFTD

Functional connectivity trajectories in genetic frontotemporal dementia.

Alzheimer's & Dementia

Liwen Zhang, Taru M. Flagan, Adam M. Staffaroni, Suvi Häkkinen, Jesse A. Brown, Maria Luisa Mandelli, Howard J. Rosen, Kejal Kantarci, Eliana Marisa Ramos, Maria Luisa Gorno Tempini, Bruce L Miller, William W. Seeley, Suzee E. Lee, ARTFL/LEFFTDS/ALLFTD Consortia

Global platform trial design for tau (MAPT) mutation carriers.

Alzheimer's & Dementia

Adam M. Staffaroni, Melanie Quintana, Barbara Wendelberger, Carmela Tartaglia, Hilary W. Heuer, Lucy L. Russell, Tania F Gendron, Leonard Petrucelli, Carolin Heller, Amy Wolf, Yann Cobigo, Mark E. Sanderson-Cimino, Leah K. Forsberg, John Kornak, David M Cash, Brad F. Boeve, Howard J. Rosen, Jonathan D. Rohrer, Adam L. Boxer, Frontotemporal Dementia Prevention Initiative Investigators

Leveraging Large-scale CSF Proteomics to identify Disease Progression Biomarkers in Autosomal Dominant Frontotemporal Lobar Degeneration.

Alzheimer's & Dementia

Rowan Saloner, Adam M. Staffaroni, Eric B. Dammer, Erik C.B. Johnson, Emily W. Paolillo, Hilary W. Heuer, Amy B. Wise, Leah K. Forsberg, Joel H. Kramer, Bruce L Miller, Jingyao Li, Joseph Loureiro, Rajeev Sivasankaran, Katie Worringer, Brad F. Boeve, Howard J. Rosen, Adam L. Boxer, Julio C. Rojas, Kaitlin B. Casaletto

Life’s Simple 7 Relates to Better Cognitive and Brain Health in Individuals with Autosomal Dominant Frontotemporal Dementia.

Alzheimer's & Dementia

Anna M VandeBunte, Joel H. Kramer, Kaitlin B. Casaletto, Emily W. Paolillo, Rowan Saloner, Hyunwoo Lee, Ging-Yuek Robin Hsiung, Adam M. Staffaroni, Shannon Y. Lee, Carmela Tartaglia, Hilary W. Heuer, Brad F. Boeve, Adam L. Boxer, Howard J. Rosen

Memory Performance in Mild Sporadic and Familial Behavioral Variant Frontotemporal Dementia: Findings from the ALLFTD Consortium.

Alzheimer's & Dementia

Brad F. Boeve, Julie A. Fields, Jeremy A. Syrjanen, Noah Johnson, Walter K. Kremers, Adam M. Staffaroni, Edward D. Huey, Katya Rascovsky, Sandra Weintraub, Eliana Marisa Ramos, David S. Knopman, Toji Miyagawa, Leah K. Forsberg, Hilary W. Heuer, Adam L Boxer, Howard J. Rosen, ALLFTD Consortium

PSMD, a novel biomarker of small vessel disease, and its association with cognitive function — A comprehensive clinical validation study.

Alzheimer's & Dementia

Alison M. Luckey, Saptaparni Ghosh, Rebecca Bernal, Haykel Snoussi, Angel G. Velarde, Hector Trevino, Monica Goss, Jayandra Jung Himali, Laura J. Hillmer, Hanzhang Lu, Konstantinos Arfanakis, Brian T. Gold, Christopher E. Bauer, Joel H. Kramer, Adam M. Staffaroni, Lara Stables, Danny J.J. Wang, Alexa S. Beiser, Myriam Fornage, Thomas H. Mosley, Gary A. Rosenberg, Baljeet Singh, Herpreet Singh, Kristin Schwab, Karl G. Helmer, Steven M. Greenberg, Mohamad Habes, Caprihan Arvind, Sudha Seshadri, Charles Decarli, Pauline Maillard, Claudia L. Satizabal

Passively monitored smartphone battery percentage relates to disease severity in frontotemporal dementia: A proof-of-concept study.

Alzheimer's & Dementia

Emily W. Paolillo, Kaitlin B. Casaletto, Annie L Clark, Jack C Taylor, Hilary W. Heuer, Amy B. Wise, Sreya Dhanam, Mark E. Sanderson-Cimino, Rowan Saloner, Joel H. Kramer, John Kornak, Walter K. Kremers, Leah K. Forsberg, Brad F. Boeve, Howard J. Rosen, Adam L. Boxer, Adam M. Staffaroni, the ALLFTD Consortium

The Role of Alzheimer’s Disease Pathology in Cognition, Brain Volume, and Plasma Biomarker Concentrations in Traumatic Encephalopathy Syndrome.

Alzheimer's & Dementia

Breton M. Asken, Jeremy A. Tanner, Lawren VandeVrede, William G Mantyh, Kaitlin B. Casaletto, Adam M. Staffaroni, David N. soleimani-Meigooni, Leslie S Gaynor, Corrina S. Fonseca, Ranjani Shankar, Harli E. Grant, Karen Smith, Argentina Lario Lago, Haiyan Xu, Renaud La Joie, Yann Cobigo, Howard J. Rosen, David C. Perry, Julio C. Rojas, Lea T. Grinberg, Bruce L Miller, Raquel C. Gardner, Kevin K.W. Wang, Joel H. Kramer, Gil D. Rabinovici

The relationship of intraindividual variability on mobile cognitive testing with age and frontotemporal dementia disease severity.

Alzheimer's & Dementia

Mark E. Sanderson-Cimino, Annie L Clark, Amy B. Wise, Sreya Dhanam, Jack C Taylor, Emily W. Paolillo, Hilary W. Heuer, Jason J. Hassenstab, Joel H. Kramer, Brad F. Boeve, Howard J. Rosen, Adam L. Boxer, Adam M. Staffaroni, ALLFTD Consortium

Unobtrusive In-Home Digital Monitoring of Frontotemporal Dementia: Feasibility and Adherence.

Alzheimer's & Dementia

Amy B. Wise, Emily W. Paolillo, Zachary T Beattie, Chao-Yi Wu, Nathaniel Rodrigues, Sarah Gothard, Hilary W. Heuer, Leah K. Forsberg, Diana Chavez, Kelsey Holiday, Mario F. Mendez, Brad F. Boeve, Adam L Boxer, Jeffrey A Kaye, Howard J. Rosen, Adam M. Staffaroni

Validation of Cerebrospinal Fluid Alpha-synuclein Assay against Autopsy in Non-Parkinson’s Disease Neurodegenerative Syndromes.

Alzheimer's & Dementia

Niyatee Samudra, Peter A. Ljubenkov, Julio C. Rojas, Adam M. Staffaroni, Fattin Wekselman, Lamoureux Jennifer, Lea T. Grinberg, Adam L. Boxer, Lawren VandeVrede

Functional connectivity trajectories in genetic frontotemporal dementia.

Alzheimer's & Dementia

Liwen Zhang, Taru M. Flagan, Adam M. Staffaroni, Suvi Häkkinen, Jesse A. Brown, Maria Luisa Mandelli, Howard J. Rosen, Kejal Kantarci, Eliana Marisa Ramos, Maria Luisa Gorno Tempini, Bruce L Miller, William W. Seeley, Suzee E. Lee

Functional network collapse in neurodegenerative disease.

bioRxiv : the preprint server for biology

Brown JA, Lee AJ, Fernhoff K, Pistone T, Pasquini L, Wise AB, Staffaroni AM, Mandelli ML, Lee SE, Boxer AL, Rankin KP, Rabinovici GD, Tempini MLG, Rosen HJ, Kramer JH, Miller BL, Seeley WW, Alzheimer’s Disease Neuroimaging Initiative (ADNI)

50 Effects of Cerebrovascular Risk Factors and Alzheimer’s Disease Pathology on Executive Function and Memory Changes: Analysis of the National Alzheimer’s Coordinating Center Cohort.

Journal of the International Neuropsychological Society

Ankita Chatterjee, Shannon Lee, Valentina Diaz, Kaitlin B Casaletto, Adam M Staffaroni, Joel H Kramer

6 Remote Smartphone Cognitive and Motor Testing in Frontotemporal Dementia Research: Feasibility, Reliability, and Validity.

Journal of the International Neuropsychological Society

Adam M Staffaroni, Jack Carson Taylor, Annie L Clark, Hilary W Heuer, Amy B Wise, Masood Manoochehri, Leah Forsberg, Carly T Mester, Meghana Roa, Danielle Brushaber, Julio C Rojas, Joel H Kramer, Bradley F Boeve, Howard J Rosen, Adam L Boxer

93 Impact of Cardiovascular Risk on Cognitive and Brain Aging in Autosomal Dominant Frontotemporal Dementia.

Journal of the International Neuropsychological Society

Anna M VandeBunte, Emily W Paolillo, Hyunwoo Lee, Ging-Yuek Robin Hsiung, Adam Staffaroni, Shannon Y Lee, Carmela Tartaglia, Hilary Heur, Joel H Kramer, Brad Boeve, Adam Boxer, Howie Rosen, Kaitlin B Casaletto

Alzheimer's pathology is associated with altered cognition, brain volume, and plasma biomarker patterns in traumatic encephalopathy syndrome.

Alzheimer's research & therapy

Asken BM, Tanner JA, Gaynor LS, VandeVrede L, Mantyh WG, Casaletto KB, Staffaroni AM, Fonseca C, Shankar R, Grant H, Smith K, Lago AL, Xu H, La Joie R, Cobigo Y, Rosen H, Perry DC, Rojas JC, Miller BL, Gardner RC, Wang KKW, Kramer JH, Rabinovici GD

Sexually dimorphic differences in angiogenesis markers predict brain aging trajectories.

bioRxiv : the preprint server for biology

Torres-Espin A, Rabadaugh H, Fitzsimons S, Harvey D, Chou A, Lindberg C, Casaletto KB, Goldberger L, Staffaroni AM, Maillard P, Miller BL, DeCarli C, Hinman JD, Ferguson AR, Kramer JH, Elahi FM

MRI free water as a biomarker for cognitive performance: Validation in the markvcid consortium.

Alzheimer's & Dementia

Pauline Maillard, Laura J. Hillmer, Hanzhang Lu, Konstantinos Arfanakis, Brian T. Gold, Christopher E. Bauer, Joel H. Kramer, Adam M. Staffaroni, Lara Stables, Danny J.J. Wang, Sudha Seshadri, Claudia L. Satizabal, Alexa S. Beiser, Mohamad Habes, Myriam Fornage, Thomas H. Mosley, Gary A. Rosenberg, Baljeet Singh, Herpreet Singh, Kristin Schwab, Roderick A Corriveau, Karl G. Helmer, Steven M. Greenberg, Charles Decarli, Caprihan Arvind

Phenoconversion and disease progression observed in mutation carriers of familial Frontotemporal Lobar Degeneration in the ALLFTD Consortium.

Alzheimer's & Dementia

Hilary W. Heuer, Annie L Clark, Danielle Brushaber, Leah K. Forsberg, Toji Miyagawa, Adam M. Staffaroni, Edward D. Huey, Brad F. Boeve, Howard J. Rosen, Adam L. Boxer, ALLFTD Investigators

Feasibility and acceptability of remote smartphone cognitive testing in frontotemporal dementia research.

Alzheimer's & dementia (Amsterdam, Netherlands)

Taylor JC, Heuer HW, Clark AL, Wise AB, Manoochehri M, Forsberg L, Mester C, Rao M, Brushaber D, Kramer J, Welch AE, Kornak J, Kremers W, Appleby B, Dickerson BC, Domoto-Reilly K, Fields JA, Ghoshal N, Graff-Radford N, Grossman M, Hall MG, Huey ED, Irwin D, Lapid MI, Litvan I, Mackenzie IR, Masdeu JC, Mendez MF, Nevler N, Onyike CU, Pascual B, Pressman P, Rankin KP, Ratnasiri B, Rojas JC, Tartaglia MC, Wong B, Gorno-Tempini ML, Boeve BF, Rosen HJ, Boxer AL, Staffaroni AM

Evaluation of Plasma Phosphorylated Tau217 for Differentiation Between Alzheimer Disease and Frontotemporal Lobar Degeneration Subtypes Among Patients With Corticobasal Syndrome.

JAMA neurology

VandeVrede L, La Joie R, Thijssen EH, Asken BM, Vento SA, Tsuei T, Baker SL, Cobigo Y, Fonseca C, Heuer HW, Kramer JH, Ljubenkov PA, Rabinovici GD, Rojas JC, Rosen HJ, Staffaroni AM, Boeve BF, Dickerson BC, Grossman M, Huey ED, Irwin DJ, Litvan I, Pantelyat AY, Tartaglia MC, Dage JL, Boxer AL

Memory Performance in Asymptomatic and Prodromal Familial Frontotemporal Lobar Degeneration: Findings from the ALLFTD Consortium (P13-6.001).

Neurology

Bradley Boeve, Julie Fields, Jeremy Syrjanen, Walter Kremers, Adam Staffaroni, Edward Huey, Katya Rascovsky, Marisa Ramos, Leah Forsberg, Hilary Heuer, Adam Boxer, Howard Rosen

Plasma inflammation for predicting phenotypic conversion and clinical progression of autosomal dominant frontotemporal lobar degeneration.

Journal of neurology, neurosurgery, and psychiatry

Asken BM, Ljubenkov PA, Staffaroni AM, Casaletto KB, Vandevrede L, Cobigo Y, Rojas-Rodriguez JC, Rankin KP, Kornak J, Heuer H, Shigenaga J, Appleby BS, Bozoki AC, Domoto-Reilly K, Ghoshal N, Huey E, Litvan I, Masdeu JC, Mendez MF, Pascual B, Pressman P, Tartaglia MC, Kremers W, Forsberg LK, Boeve BF, Boxer AL, Rosen HJ, Kramer JH, ALLFTD Consortium Investigators

Multisite ALLFTD study modeling progressive empathy loss from the earliest stages of behavioral variant frontotemporal dementia.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Toller G, Cobigo Y, Callahan P, Appleby BS, Brushaber D, Domoto-Reilly K, Forsberg LK, Ghoshal N, Graff-Radford J, Graff-Radford NR, Grossman M, Heuer HW, Kornak J, Kremers W, Lapid MI, Leger G, Litvan I, Mackenzie IR, Pascual MB, Ramos EM, Rascovsky K, Rojas JC, Staffaroni AM, Tartaglia MC, Toga A, Weintraub S, Wszolek ZK, Boeve BF, Boxer AL, Rosen HJ, Rankin KP, ALLFTD consortium

ALLFTD Mobile App Balance and Finger Tapping Tasks: Task Description and Initial Reliability and Validity Findings.

Alzheimer's & Dementia

Amy B Wise, Annie L Clark, Jack C Taylor, Hilary W. Heuer, Carly T. Mester, Meghana Rao, Danielle Brushaber, Bradley F. Boeve, Leah K. Forsberg, Joel H. Kramer, Howard J. Rosen, Adam L Boxer, Adam M. Staffaroni

Baseline Reliability and Six-Month Stability of a Remotely Administered Battery of Smartphone Cognitive Tests.

Alzheimer's & Dementia

Jack C Taylor, Annie L Clark, Hilary W. Heuer, Amy B Wise, Masood Manoochehri, Leah K. Forsberg, Carly T. Mester, Meghana Rao, Danielle Brushaber, Joel H. Kramer, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer, Adam M. Staffaroni

Construct Validity of the ALLFTD Mobile App Cognitive Tests: Associations with Gold Standard Clinical Measures and Brain Volume.

Alzheimer's & Dementia

Adam M. Staffaroni, Annie L Clark, Jack C Taylor, Hilary W. Heuer, Amy B Wise, Masood Manoochehri, Leah K. Forsberg, Carly T. Mester, Meghana Rao, Danielle Brushaber, Julio C. Rojas, Joel H. Kramer, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer, ALLFTD Consortium

Introduction to Veri-T: A Phase 1 Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of Verdiperstat in Patients with svPPA Due to FTLD-TDP.

Alzheimer's & Dementia

Peter A. Ljubenkov, Adam M. Staffaroni, Julio C. Rojas, Lawren VandeVrede, Mary Koestler, Tayler A Sulse, Julia Moreton, Sheena Horiki, Hilary W. Heuer, Ian Grant, David J. Irwin, Bradley F. Boeve, Howard J. Rosen, David S. Knopman, Robert Bowser, Murray Grossman, Irfan Qureshi, Adam L. Boxer

Sex modifies the association between hippocampal blood flow and episodic memory in cognitively unimpaired individuals.

Alzheimer's & Dementia

Anna Brugulat-Serrat, Yann Cobigo, Corrina S. Fonseca, Torie Tsuei, Lauren Goldberger, Howard J. Rosen, Joel H. Kramer, Fanny M Elahi, Adam M. Staffaroni, Kaitlin B Casaletto

The Collaboration and Harmonization of Digital Biomarkers for Alzheimer’s Research.

Alzheimer's & Dementia

Zachary T Beattie, Sarah Gothard, Lisa L. Barnes, Shayla Calloway, Mitzi M Gonzales, Brian D Jones, Tiffany F Kautz, Allan I. Levey, Julia J Mathews, Rachel Mulavelil, Brenna Phelps, Howard J. Rosen, Agata Rozga, Sudha Seshadri, Adam M. Staffaroni, Dara K Wasserman, Amy B Wise, Jeffrey A Kaye

The Collaboration and Harmonization of Digital Biomarkers for Alzheimer’s Research.

Alzheimer's & Dementia

Zachary T Beattie, Sarah Gothard, Lisa L. Barnes, Shayla Calloway, Mitzi M Gonzales, Brian D Jones, Tiffany F Kautz, Allan I. Levey, Julia J Mathews, Rachel Mulavelil, Brenna Phelps, Howard J. Rosen, Agata Rozga, Sudha Seshadri, Adam M. Staffaroni, Dara K Wasserman, Amy B Wise, Jeffrey A Kaye

MRI free water as a biomarker for cognitive performance: Validation in the MarkVCID consortium.

Alzheimer's & dementia (Amsterdam, Netherlands)

Maillard P, Hillmer LJ, Lu H, Arfanakis K, Gold BT, Bauer CE, Kramer JH, Staffaroni AM, Stables L, Wang DJJ, Seshadri S, Satizabal CL, Beiser A, Habes M, Fornage M, Mosley TH, Rosenberg GA, Singh B, Singh H, Schwab K, Helmer KG, Greenberg SM, DeCarli C, Caprihan A

Age-related brain atrophy is not a homogenous process: Different functional brain networks associate differentially with aging and blood factors.

Proceedings of the National Academy of Sciences of the United States of America

Markov NT, Lindbergh CA, Staffaroni AM, Perez K, Stevens M, Nguyen K, Murad NF, Fonseca C, Campisi J, Kramer J, Furman D

Temporal order of clinical and biomarker changes in familial frontotemporal dementia.

Nature medicine

Staffaroni AM, Quintana M, Wendelberger B, Heuer HW, Russell LL, Cobigo Y, Wolf A, Goh SM, Petrucelli L, Gendron TF, Heller C, Clark AL, Taylor JC, Wise A, Ong E, Forsberg L, Brushaber D, Rojas JC, VandeVrede L, Ljubenkov P, Kramer J, Casaletto KB, Appleby B, Bordelon Y, Botha H, Dickerson BC, Domoto-Reilly K, Fields JA, Foroud T, Gavrilova R, Geschwind D, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grossman M, Hall MGH, Hsiung GY, Huey ED, Irwin D, Jones DT, Kantarci K, Kaufer D, Knopman D, Kremers W, Lago AL, Lapid MI, Litvan I, Lucente D, Mackenzie IR, Mendez MF, Mester C, Miller BL, Onyike CU, Rademakers R, Ramanan VK, Ramos EM, Rao M, Rascovsky K, Rankin KP, Roberson ED, Savica R, Tartaglia MC, Weintraub S, Wong B, Cash DM, Bouzigues A, Swift IJ, Peakman G, Bocchetta M, Todd EG, Convery RS, Rowe JB, Borroni B, Galimberti D, Tiraboschi P, Masellis M, Finger E, van Swieten JC, Seelaar H, Jiskoot LC, Sorbi S, Butler CR, Graff C, Gerhard A, Langheinrich T, Laforce R, Sanchez-Valle R, de Mendonça A, Moreno F, Synofzik M, Vandenberghe R, Ducharme S, Le Ber I, Levin J, Danek A, Otto M, Pasquier F, Santana I, Kornak J, Boeve BF, Rosen HJ, Rohrer JD, Boxer AL, Frontotemporal Dementia Prevention Initiative (FPI) Investigators

Detection of emerging neurodegeneration using Bayesian linear mixed-effect modeling.

NeuroImage. Clinical

Cobigo Y, Goh MS, Wolf A, Staffaroni AM, Kornak J, Miller BL, Rabinovici GD, Seeley WW, Spina S, Boxer AL, Boeve BF, Wang L, Allegri R, Farlow M, Mori H, Perrin RJ, Kramer J, Rosen HJ, Alzheimer’s Disease Neuroimaging Initiative (ADNI) and the Dominantly Inherited Alzheimer’s Network

Sensitivity of the Social Behavior Observer Checklist to Early Symptoms of Patients With Frontotemporal Dementia.

Neurology

Toller G, Cobigo Y, Ljubenkov PA, Appleby BS, Dickerson BC, Domoto-Reilly K, Fong JC, Forsberg LK, Gavrilova RH, Ghoshal N, Heuer HW, Knopman DS, Kornak J, Lapid MI, Litvan I, Lucente DE, Mckenzie IR, McGinnis SM, Miller BL, Pedraza O, Rojas JC, Staffaroni AM, Wong B, Wszolek ZK, Boeve BF, Boxer AL, Rosen HJ, Rankin KP, ALLFTD research consortium

Retinal arteriolar parameters as a surrogate marker of intracranial vascular pathology.

Alzheimer's & dementia (Amsterdam, Netherlands)

Abdelhak A, Solomon I, Montes SC, Saias A, Cordano C, Asken B, Fonseca C, Oertel FC, Arfanakis K, Staffaroni AM, Kramer JH, Geschwind M, Miller BL, Elahi FM, Green AJ

Multimodal Biomarkers of Repetitive Head Impacts and Traumatic Encephalopathy Syndrome: A Clinico-Pathological Case Series.

Journal of neurotrauma

Asken B, Tanner JA, VandeVrede L, Casaletto KB, Staffaroni AM, Mundada N, Fonseca C, Iaccarino L, La Joie R, Tsuei T, Mladinov M, Grant H, Shankar R, Wang KKW, Xu H, Cobigo Y, Rosen H, Gardner RC, Perry DC, Miller BL, Spina S, Seeley WW, Kramer J, Grinberg LT, Rabinovici G

Plasma P-tau181 and P-tau217 in Patients With Traumatic Encephalopathy Syndrome With and Without Evidence of Alzheimer Disease Pathology.

Neurology

Asken BM, Tanner JA, VandeVrede L, Mantyh WG, Casaletto KB, Staffaroni AM, La Joie R, Iaccarino L, Soleimani-Meigooni D, Rojas JC, Gardner RC, Miller BL, Grinberg LT, Boxer AL, Kramer JH, Rabinovici GD

Proposed research criteria for prodromal behavioural variant frontotemporal dementia.

Brain : a journal of neurology

Barker MS, Gottesman RT, Manoochehri M, Chapman S, Appleby BS, Brushaber D, Devick KL, Dickerson BC, Domoto-Reilly K, Fields JA, Forsberg LK, Galasko DR, Ghoshal N, Goldman J, Graff-Radford NR, Grossman M, Heuer HW, Hsiung GY, Knopman DS, Kornak J, Litvan I, Mackenzie IR, Masdeu JC, Mendez MF, Pascual B, Staffaroni AM, Tartaglia MC, Boeve BF, Boxer AL, Rosen HJ, Rankin KP, Cosentino S, Rascovsky K, Huey ED, ALLFTD Consortium

Association of Genetic Variants Linked to Late-Onset Alzheimer Disease With Cognitive Test Performance by Midlife.

JAMA network open

Zimmerman SC, Brenowitz WD, Calmasini C, Ackley SF, Graff RE, Asiimwe SB, Staffaroni AM, Hoffmann TJ, Glymour MM

Cross-national harmonization of cognitive measures across HRS HCAP (USA) and LASI-DAD (India).

PloS one

Vonk JMJ, Gross AL, Zammit AR, Bertola L, Avila JF, Jutten RJ, Gaynor LS, Suemoto CK, Kobayashi LC, O'Connell ME, Elugbadebo O, Amofa PA, Staffaroni AM, Arce Rentería M, Turney IC, Jones RN, Manly JJ, Lee J, Zahodne LB

Author Correction: Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans.

Scientific reports

Elahi FM, Harvey D, Altendahl M, Brathaban N, Fernandes N, Casaletto KB, Staffaroni AM, Maillard P, Hinman JD, Miller BL, DeCarli C, Kramer JH, Goetzl EJ

A remote smartphone cognitive testing battery for frontotemporal dementia: Completion rate, reliability, and validity.

Alzheimer's & Dementia

Adam M. Staffaroni, Jack C Taylor, Annie L Clark, Hilary W. Heuer, Leah K. Forsberg, Riley Bahl, Masood Manoochehri, Stephanie Vento, Lynn P. Bajorek, Elise Ong, Michelle You, Bradley F. Boeve, Joel H Kramer, Howard J. Rosen, Adam L. Boxer

Changes in wall thickness of retinal arterioles as a surrogate marker of intracranial vascular pathology.

Alzheimer's & Dementia

Ahmed Abdelhak, Isaac Solomon, Alexandra Saias, Shivany Condor Montes, Christian Cordano, Breton Asken, Corrina Fonseca, Frederike Cosima Oertel, Konstantinos Arfanakis, Adam M. Staffaroni, Michael Geschwind, Fanny M. Elahi, Ari J. Green

Clinical features that differentiate young-onset AD from young-onset FTLD: An examination of the NACC UDS 3.0 and FTLD Module.

Alzheimer's & Dementia

Sheena Isha Dev, Bonnie Wong, Megan Quimby, Ani Eloyan, Adam M. Staffaroni, Katya Rascovsky, Sandra Weintraub, Julie A. Fields, Katherine P Rankin, Walter A. Kukull, Hilary W. Heuer, Leah K. Forsberg, Danielle Brushaber, Bradley F. Boeve, Howard J. Rosen, Adam L Boxer, Maria C. Carrillo, Gil D. Rabinovici, Liana G. Apostolova, Brad C. Dickerson, Riley Bahl, the ALLFTD and LEADS Consortium Studies

Disease progression models of familial frontotemporal lobar degeneration and the temporal ordering of biomarker changes in an international cohort.

Alzheimer's & Dementia

Adam M. Staffaroni, Melanie Quintana, Barbara Wendelberger, Lucy L. Russell, Leonard Petrucelli, Tania F. Gendron, Sheng-Yang Matthew Goh, Yann Cobigo, Amy Wolf, Hilary W. Heuer, David M. Cash, Elise Ong, Leah K. Forsberg, Danielle Brushaber, Riley Bahl, Carolin Heller, Arabella Bouzigues, Imogen J. Swift, Georgia Peakman, Martina Bocchetta, Emily G. Todd, Rhian S. Convery, Bradley F. Boeve, Howard J. Rosen, Jonathan D. Rohrer, Adam L. Boxer, ALLFTD and GENFI

Sex differences in the behavioral variant of frontotemporal dementia: A new window to executive and behavioral reserve.

Alzheimer's & Dementia

Ignacio Illán-Gala, Kaitlin B. Casaletto, Sergi Borrego-Écija, Eider M Arenaza-Urquijo, Amy Wolf, Yann Cobigo, Sheng-Yang Matthew Goh, Adam M. Staffaroni, Daniel Alcolea, Juan Fortea, Rafael Blesa, Jordi Clarimon, M. Florencia Iulita, Anna Brugulat-Serrat, Albert Lladó, Lea T. Grinberg, Kate L Possin, Katherine P Rankin, Joel H Kramer, Gil D. Rabinovici, Adam L. Boxer, William W. Seeley, Virginia Sturm, Maria Luisa Gorno Tempini, Bruce L. Miller, Raquel Sanchez-Valle, David C. Perry, Alberto Lleó, Howard J. Rosen

Clinical value of CSF tau, p-tau181, neurogranin and neurofilaments in familial frontotemporal lobar degeneration.

Alzheimer's & Dementia

Julio C. Rojas, Hilary W. Heuer, Weiping Chen, Julie Czerkowicz, Danielle Graham, Leah K. Forsberg, Danielle Brushaber, Brian Appleby, Eliana Marisa Ramos, Giovanni Coppolla, Yvette M. Bordelon, Hugo Botha, Brad C. Dickerson, Dennis W. Dickson, Kimiko Domoto-Reilly, Anne M. Fagan, Julie A. Fields, Jamie C. Fong, Tatiana M. Foroud, Doug R. Galasko, Ralitza H. Gavrilova, Daniel H. Geschwind, Nupur Ghoshal, Jill Goldman, Neill R. Graff-Radford, Jonathan Graff-Radford, Ian Grant, Murray Grossman, Ging-Yuek Robin Hsiung, Eric J. Huang, Edward D. Huey, David J. Irwin, David T. Jones, Kejal Kantarci, David S. Knopman, John Kornak, Walter K. Kremers, Maria I. Lapid, Gabriel C. Leger, Irene Litvan, Peter A. Ljubenkov, Diane E. Lucente, Ian R Mackenzie, Joseph C. Masdeu, Corey T. McMillan, Mario F. Mendez, Bruce L. Miller, Toji Miyagawa, Chiadi U. Onyike, Belen Pascual, Otto Pedraza, Leonard Petrucelli, Rosa Rademakers, Katherine P. Rankin, Katya Rascovsky, Jessica E. Rexach, Aaron Ritter, Erik D. Roberson, Rodolfo Savica, William W. Seeley, Adam M. Staffaroni, Maria Carmela Tartaglia, Arthur W. Toga, Sandra Weintraub, Bonnie Wong, Zbigniew Wszolek, Lawren Vandevrede, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer

Demographic and psychosocial factors associated with the decision to learn mutation status in familial frontotemporal dementia and the impact of disclosure on mood.

Alzheimer's & Dementia

Lynn P. Bajorek, Rachel Kiekhofer, Matthew Hall, Joanne Taylor, Diane E Lucente, Danielle Brushaber, Brian Appleby, Giovanni Coppolla, Yvette M Bordelon, Hugo Botha, Brad C Dickerson, Dennis W Dickson, Kimiko Domoto-Reilly, Anne M Fagan, Julie A Fields, Jamie C Fong, Tatiana M Foroud, Leah K Forsberg, Doug R Galasko, Ralitza H Gavrilova, Daniel H Geschwind, Nupur Ghoshal, Jill Goldman, Neill R Graff-Radford, Jonathan Graff-Radford, Ian Grant, Murray Grossman, Hilary W Heuer, Ging-Yuek Robin Hsiung, Eric J Huang, Edward D Huey, David J Irwin, David T Jones, Kejal Kantarci, John Kornak, Walter K Kremers, Maria I Lapid, Gabriel C Leger, Irene Litvan, Peter A Ljubenkov, Ian R Mackenzie, Joseph C Masdeu, Corey McMillan, Mario Mendez, Bruce L Miller, Toji Miyagawa, Chiadi U Onyike, Belen Pascual, Otto Pedraza, Leonard Petrucelli, Rosa Rademakers, Eliana Marisa Ramos, Katherine P Rankin, Katya Rascovsky, Jessica E Rexach, Aaron Ritter, Erik D. Roberson, Rodolfo Savica, Julio C Rojas, William W Seeley, Maria Carmela Tartaglia, Arthur W Toga, Sandra Weintraub, Bonnie Wong, Zbigniew Wszolek, Lawren Vandevrede, Bradley F Boeve, Adam L Boxer, Howard J Rosen, Adam M Staffaroni, ALLFTD Consortium

Diagnostic value of plasma P-tau217 in frontotemporal dementia spectrum disorders.

Alzheimer's & Dementia

Julio C. Rojas, Lawren Vandevrede, Hilary W. Heuer, Gianina Toller, Elisabeth H. Thijssen, Nicholas Proctor, Leah K. Forsberg, Danielle Brushaber, Eliana Marisa Ramos, Giovanni Coppola, Brian Appleby, Yvette M. Bordelon, Hugo Botha, Brad C. Dickerson, Dennis W. Dickson, Kimiko Domoto-Reilly, Anne M. Fagan, Julie A. Fields, Jamie C. Fong, Tatiana M. Foroud, Doug R. Galasko, Ralitza H. Gavrilova, Daniel H. Geschwind, Nupur Ghoshal, Jill Goldman, Neill R. Graff-Radford, Jonathan Graff-Radford, Ian Grant, Murray Grossman, Ging-Yuek Robin Hsiung, Eric J. Huang, Edward D. Huey, David J. Irwin, David T. Jones, Kejal Kantarci, David S. Knopman, John Kornak, Walter K. Kremers, Maria I. Lapid, Gabriel C. Leger, Irene Litvan, Peter A. Ljubenkov, Diane E. Lucente, Ian R. Mackenzie, Joseph C. Masdeu, Corey T. McMillan, Mario Mendez, Bruce L. Miller, Toji Miyagawa, Chiadi U. Onyike, Belen Pascual, Otto Pedraza, Leonard Petrucelli, Rosa Rademakers, Katherine P. Rankin, Katya Rascovsky, Jessica E. Rexach, Aaron Ritter, Erik D. Roberson, Rodolfo Savica, William W. Seeley, Adam M. Staffaroni, Maria Carmela Trataglia, Arthur W. Toga, Sandra Weintraub, Bonnie Wong, Zbigniew Wszolek, Jeffrey L. Dage, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer

Gearing up for the future: Exploring facilitators and barriers to inform clinical trial design in frontotemporal lobar degeneration.

Alzheimer's & Dementia

Yasmin B Banga, Yujung Lai, Priscilla Kim, Bradley F Boeve, Adam L Boxer, Howard J Rosen, Leah K Forsberg, Hilary W Heuer, Danielle Brushaber, Brian Appleby, Joanna M Biernacka, Yvette M Bordelon, Hugo Botha, Andrea C Bozoki, Patrick Brannelly, Brad C Dickerson, Susan Dickinson, Dennis W Dickson, Kimiko Domoto-Reilly, Kelley Faber, Anne M Fagan, Julie A Fields, Ann Fishman, Tatiana M Foroud, Doug R Galasko, Ralitza H Gavrilova, Tania F Gendron, Daniel H Geschwind, Nupur Ghoshal, Jill Goldman, Jonathan Graff-Radford, Neill R Graff-Radford, Ian Grant, Murray Grossman, Ging-Yuek Robin Hsiung, Eric J Huang, Edward D Huey, David J Irwin, David T Jones, Kejal Kantarci, Anna M Karydas, Daniel Kaufer, David S Knopman, Joel H Kramer, Walter K Kremers, John Kornak, Walter A Kukull, Emma Lagone, Gabriel C Leger, Irene Litvan, Peter A Ljubenkov, Diane E Lucente, Ian R Mackenzie, Masood Manoochehri, Joseph C Masdeu, Scott McGinnis, Mario F Mendez, Bruce L Miller, Toji Miyagawa, Kevin M Nelson, Chiadi U Onyike, Alex Pantelyat, Belen Pascual, Rodney Pearlman, Leonard Petrucelli, Cyril P Pottier, Rosa Rademakers, Eliana Marisa Ramos, Katherine P Rankin, Katya Rascovsky, Jessica E Rexach, Aaron Ritter, Erik D Roberson, Julio C Rojas, Marwan N Sabbagh, David P Salmon, Rodolfo Savica, William W Seeley, Adam M Staffaroni, Jeremy A Syrjanen, Maria Carmela Tartaglia, Nadine Tatton, Jack C Taylor, Arthur W Toga, Sandra Weintraub, Diana Wheaton, Benjamin Wong, Zbigniew Wszolek, ALLFTD Consortium

Inter-Batch Reliability of Blood-Based Cytokine and Chemokine Measurements in Community-Dwelling Older Adults: A Cross-Sectional Study.

The journals of gerontology. Series A, Biological sciences and medical sciences

Lindbergh CA, Asken BM, Casaletto KB, Elahi FM, Goldberger LA, Fonseca C, You M, Apple AC, Staffaroni AM, Fitch R, Rivera Contreras W, Wang P, Karydas A, Kramer JH, Hillblom Aging Network

Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans.

Scientific reports

Elahi FM, Harvey D, Altendahl M, Brathaban N, Fernandes N, Casaletto KB, Staffaroni AM, Maillard P, Hinman JD, Miller BL, DeCarli C, Kramer JH, Goetzl EJ

Pattern and degree of individual brain atrophy predicts dementia onset in dominantly inherited Alzheimer's disease.

Alzheimer's & dementia (Amsterdam, Netherlands)

Keret O, Staffaroni AM, Ringman JM, Cobigo Y, Goh SM, Wolf A, Allen IE, Salloway S, Chhatwal J, Brickman AM, Reyes-Dumeyer D, Bateman RJ, Benzinger TLS, Morris JC, Ances BM, Joseph-Mathurin N, Perrin RJ, Gordon BA, Levin J, Vöglein J, Jucker M, la Fougère C, Martins RN, Sohrabi HR, Taddei K, Villemagne VL, Schofield PR, Brooks WS, Fulham M, Masters CL, Ghetti B, Saykin AJ, Jack CR, Graff-Radford NR, Weiner M, Cash DM, Allegri RF, Chrem P, Yi S, Miller BL, Rabinovici GD, Rosen HJ, Dominantly Inherited Alzheimer Network

Building clinically relevant outcomes across the Alzheimer's disease spectrum.

Alzheimer's & dementia (New York, N. Y.)

Rentz DM, Wessels AM, Annapragada AV, Berger AK, Edgar CJ, Gold M, Miller DS, Randolph C, Ryan JM, Wunderlich G, Zoschg MC, Trépel D, Knopman DS, Staffaroni AM, Bain LJ, Carrillo MC, Weber CJ

Lower White Matter Volume and Worse Executive Functioning Reflected in Higher Levels of Plasma GFAP among Older Adults with and Without Cognitive Impairment.

Journal of the International Neuropsychological Society : JINS

Asken BM, VandeVrede L, Rojas JC, Fonseca C, Staffaroni AM, Elahi FM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Boxer AL, Miller BL, Rosen HJ, Kramer JH, Casaletto KB

Retinal imaging demonstrates reduced capillary density in clinically unimpaired APOE ε4 gene carriers.

Alzheimer's & dementia (Amsterdam, Netherlands)

Elahi FM, Ashimatey SB, Bennett DJ, Walters SM, La Joie R, Jiang X, Wolf A, Cobigo Y, Staffaroni AM, Rosen HJ, Miller BL, Rabinovici GD, Kramer JH, Green AJ, Kashani AH

Wisdom and fluid intelligence are dissociable in healthy older adults.

International psychogeriatrics

Lindbergh CA, Romero-Kornblum H, Weiner-Light S, Young JC, Fonseca C, You M, Wolf A, Staffaroni AM, Daly R, Jeste DV, Kramer JH, Chiong W, Hillblom Aging Network

A Comparative Study of Plasma t-tau and Neurofilament Light Chain in Frontotemporal Lobar Degeneration and Alzheimer’s Disease (1305).

Neurology

Ignacio Illan-Gala, Alberto Lleo, Adam Staffaroni, Henrik Zetterberg, Agnieszka Kieloch, Lea Grinberg, Salvatore Spina, Joel Kramer, Eliana Marisa Ramos, Giovanni Coppola, Renaud La Joie, Gil Rabinovici, David Perry, Maria Luisa Gorno-Tempini, William Seeley, Bruce Miller, Howard Rosen, Adam Boxer, Julio Rojas

Characterization of a large single-site USA CADASIL cohort (2437).

Neurology

Jennifer Zitser-Koren, Daven Crossland, Theresa Driscoll, Michael Terranova, Sasha Saias, Jane Paulsen, Adam Staffaroni, Katherine Possin, Fanny Elahi, Michael Geschwind

APOE moderates the effect of hippocampal blood flow on memory pattern separation in clinically normal older adults.

Hippocampus

Memel M, Staffaroni AM, Cobigo Y, Casaletto KB, Fonseca C, Bettcher BM, Yassa MA, Elahi FM, Wolf A, Rosen HJ, Kramer JH

Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration.

Neurology

Rojas JC, Wang P, Staffaroni AM, Heller C, Cobigo Y, Wolf A, Goh SM, Ljubenkov PA, Heuer HW, Fong JC, Taylor JB, Veras E, Song L, Jeromin A, Hanlon D, Yu L, Khinikar A, Sivasankaran R, Kieloch A, Valentin MA, Karydas AM, Mitic LL, Pearlman R, Kornak J, Kramer JH, Miller BL, Kantarci K, Knopman DS, Graff-Radford N, Petrucelli L, Rademakers R, Irwin DJ, Grossman M, Ramos EM, Coppola G, Mendez MF, Bordelon Y, Dickerson BC, Ghoshal N, Huey ED, Mackenzie IR, Appleby BS, Domoto-Reilly K, Hsiung GR, Toga AW, Weintraub S, Kaufer DI, Kerwin D, Litvan I, Onyike CU, Pantelyat A, Roberson ED, Tartaglia MC, Foroud T, Chen W, Czerkowicz J, Graham DL, van Swieten JC, Borroni B, Sanchez-Valle R, Moreno F, Laforce R, Graff C, Synofzik M, Galimberti D, Rowe JB, Masellis M, Finger E, Vandenberghe R, de Mendonça A, Tagliavini F, Santana I, Ducharme S, Butler CR, Gerhard A, Levin J, Danek A, Otto M, Sorbi S, Cash DM, Convery RS, Bocchetta M, Foiani M, Caroline V G, Peakman G, Russell L, Swift I, Todd E, Rohrer JD, Boeve BF, Rosen HJ, Boxer AL

The Rapid Naming Test: Development and initial validation in typically aging adults.

The Clinical neuropsychologist

Stiver J, Staffaroni AM, Walters SM, You MY, Casaletto KB, Erlhoff SJ, Possin KL, Lukic S, La Joie R, Rabinovici GD, Zimmerman ME, Gorno-Tempini ML, Kramer JH

Recognition memory and divergent cognitive profiles in prodromal genetic frontotemporal dementia.

Cortex; a journal devoted to the study of the nervous system and behavior

Barker MS, Manoochehri M, Rizer SJ, Appleby BS, Brushaber D, Dev SI, Devick KL, Dickerson BC, Fields JA, Foroud TM, Forsberg LK, Galasko DR, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Hsiung GY, Kornak J, Litvan I, Mackenzie IR, Mendez MF, Pascual B, Rankin KP, Rascovsky K, Staffaroni AM, Tartaglia MC, Weintraub S, Wong B, Boeve BF, Boxer AL, Rosen HJ, Goldman J, Huey ED, Cosentino S, ALLFTD consortium

Enhanced Stress Resilience Training in Surgeons: Iterative Adaptation and Biopsychosocial Effects in 2 Small Randomized Trials.

Annals of surgery

Lebares CC, Coaston TN, Delucchi KL, Guvva EV, Shen WT, Staffaroni AM, Kramer JH, Epel ES, Hecht FM, Ascher NL, Harris HW, Cole SW

Uniform data set language measures for bvFTD and PPA diagnosis and monitoring.

Alzheimer's & dementia (Amsterdam, Netherlands)

Staffaroni AM, Weintraub S, Rascovsky K, Rankin KP, Taylor J, Fields JA, Casaletto KB, Hillis AE, Lukic S, Gorno-Tempini ML, Heuer H, Teylan MA, Kukull WA, Miller BL, Boeve BF, Rosen HJ, Boxer AL, Kramer JH

Sex differences in the behavioral variant of frontotemporal dementia: A new window to executive and behavioral reserve.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Illán-Gala I, Casaletto KB, Borrego-Écija S, Arenaza-Urquijo EM, Wolf A, Cobigo Y, Goh SYM, Staffaroni AM, Alcolea D, Fortea J, Blesa R, Clarimon J, Iulita MF, Brugulat-Serrat A, Lladó A, Grinberg LT, Possin K, Rankin KP, Kramer JH, Rabinovici GD, Boxer A, Seeley WW, Sturm VE, Gorno-Tempini ML, Miller BL, Sánchez-Valle R, Perry DC, Lleó A, Rosen HJ

A novel temporal-predominant neuro-astroglial tauopathy associated with TMEM106B gene polymorphism in FTLD/ALS-TDP.

Brain pathology (Zurich, Switzerland)

Llibre-Guerra JJ, Lee SE, Suemoto CK, Ehrenberg AJ, Kovacs GG, Karydas A, Staffaroni A, De Paula Franca Resende E, Kim EJ, Hwang JH, Ramos EM, Wojta KJ, Pasquini L, Pang SY, Spina S, Allen IE, Kramer J, Miller BL, Seeley WW, Grinberg LT

Mild Motor Signs Matter in Typical Brain Aging: The Value of the UPDRS Score Within a Functionally Intact Cohort of Older Adults.

Frontiers in aging neuroscience

Zitser J, Casaletto KB, Staffaroni AM, Sexton C, Weiner-Light S, Wolf A, Brown JA, Miller BL, Kramer JH

Evaluation of Cerebral Blood Flow Measured by 3D PCASL as Biomarker of Vascular Cognitive Impairment and Dementia (VCID) in a Cohort of Elderly Latinx Subjects at Risk of Small Vessel Disease.

Frontiers in neuroscience

Jann K, Shao X, Ma SJ, Cen SY, D'Orazio L, Barisano G, Yan L, Casey M, Lamas J, Staffaroni AM, Kramer JH, Ringman JM, Wang DJJ

Association of remote mild traumatic brain injury with cortical amyloid burden in clinically normal older adults.

Brain imaging and behavior

Asken BM, Mantyh WG, La Joie R, Strom A, Casaletto KB, Staffaroni AM, Apple AC, Lindbergh CA, Iaccarino L, You M, Grant H, Fonseca C, Windon C, Younes K, Tanner J, Rabinovici GD, Kramer JH, Gardner RC

Plasma Glial Fibrillary Acidic Protein Levels Differ Along the Spectra of Amyloid Burden and Clinical Disease Stage.

Journal of Alzheimer's disease : JAD

Asken BM, Elahi FM, La Joie R, Strom A, Staffaroni AM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Karydas A, Wang P, Rojas JC, Boxer AL, Miller BL, Rabinovici GD, Kramer JH, Casaletto KB

Multimodal MRI staging for tracking progression and clinical-imaging correlation in sporadic Creutzfeldt-Jakob disease.

NeuroImage. Clinical

Sacco S, Paoletti M, Staffaroni AM, Kang H, Rojas J, Marx G, Goh SY, Luisa Mandelli M, Allen IE, Kramer JH, Bastianello S, Henry RG, Rosen HJ, Caverzasi E, Geschwind MD

Latent disease models estimate symptom onset in familial frontotemporal lobar degeneration and enable novel designs for early-stage clinical trials.

Alzheimer's & Dementia

Adam M. Staffaroni, Melanie Quintana, Barbara Wendelberger, Hilary W. Heuer, Julio C. Rojas, Yann Cobigo, Sheng-Yang Matthew Goh, Amy Wolf, Chiadi U. Onyike, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer

Neuropsychiatric abnormalities in familial frontotemporal dementia: Findings from the LEFFTDS Cohort.

Alzheimer's & Dementia

Leah K. Forsberg, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer, Jeremy Syrjanen, Danielle Brushaber, Giovanni Coppolla, Brad C. Dickerson, Julie A. Fields, Jamie Fong, Ralitza H. Gavrilova, Nupur Ghoshal, Jill Goldman, Jonathan Graff-Radford, Neill R. Graff-Radford, Murray Grossman, Hilary W. Heuer, Ging-Yuek Robin Hsiung, Edward Huey, David J. Irwin, David T. Jones, Kejal Kantarci, Anna M. Karydas, David S. Knopman, John Kornak, Joel H. Kramer, Walter K. Kremers, Walter A. Kukull, Peter A. Ljubenkov, Ian R. Mackenzie, Scott McGinnis, Bruce L. Miller, Rosa Rademakers, Eliana Marisa Ramos, Katherine Rankin, Katya Rascovsky, Virginia Sturm, Adam M. Staffaroni, Joanne Taylor, Bonnie Wong, Zbigniew Wszolek

Pilot study of remote monitoring technologies for frontotemporal lobar degeneration (REMOTE FTLD): Feasibility and compliance.

Alzheimer's & Dementia

Jack Carson Taylor, Hilary W Heuer, Stephanie Vento, Lynn Bajorek, Elise Ong, Ping Wang, Michelle You, Howard J Rosen, Adam M Staffaroni, Adam L Boxer

Plasma biomarkers of inflammation reflect disease state in autosomal dominant forms of familial frontotemporal dementia.

Alzheimer's & Dementia

Peter A. Ljubenkov, Adam M. Staffaroni, Kaitlin B. Casaletto, Julio C. Rojas, Lawren Vandevrede, Hilary W. Heuer, Fanny M. Elahi, Danielle Brushaber, Tatiana M. Foroud, Leah K. Forsberg, Anna M. Karydas, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer, Joel H. Kramer, ARTFL and LEFFTDS Consortium Investigators

Studying the natural history of frontotemporal lobar degeneration (FTLD): The ARTFL LEFFTDS longitudinal FTLD (ALLFTD) protocol.

Alzheimer's & Dementia

Bradley F. Boeve, Adam L. Boxer, Howard J. Rosen, Leah K. Forsberg, Hilary W. Heuer, Danielle Brushaber, Brian Appleby, Joanna M. Biernacka, Yvette M. Bordelon, Hugo Botha, Patrick Brannelly, Brad C. Dickerson, Dennis W. Dickson, Domoto-Reilly Kimiko, Kelley Faber, Anne Fagan, Julie A. Fields, Ann Fishman, Tatiana M. Foroud, Doug R. Galasko, Ralitza H. Gavrilova, Tania F. Gendron, Daniel H. Geschwind, Nupur Ghoshal, Jill Goldman, Jonathan Graff-Radford, Neill R. Graff-Radford, Ian Grant, Murray Grossman, Ging-Yuek Robin Hsiung, Eric J. Huang, Edward Huey, David J. Irwin, David T. Jones, Kejal Kantarci, Anna M. Karydas, Daniel Kaufer, David S. Knopman, Joel H. Kramer, Walter K. Kremers, John Kornak, Walter A. Kukull, Emma Lagone, Gabriel C. Leger, Irene Litvan, Peter A. Ljubenkov, Diane E Lucente, Ian R Mackenzie, Masood Manoochehri, Joseph C. Masdeu, Scott McGinnis, Mario F. Mendez, Bruce L. Miller, Toji Miyagawa, Kevin M. Nelson, Chiadi U Onyike, Alex Pantelyat, Belen Pascual, Rodney Pearlman, Leonard Petrucelli, Rosa Rademakers, Eliana Marisa Ramos, Katherine Rankin, Katya Rascovsky, Jessica E. Rexach, Aaron Ritter, Erik D. Roberson, Julio C. Rojas, Marwan N. Sabbagh, David P. Salmon, Rodolfo Savica, William W. Seeley, Adam M. Staffaroni, Jeremy Syrjanen, Carmela Tartaglia, Nadine Tatton, Joanne Taylor, Arthur W. Toga, Sandra Weintraub, Diana Wheaton, Bonnie Wong, Zbigniew Wszolek

The evolution of brain atrophy across the disease spectrum of familial frontotemporal dementia.

Alzheimer's & Dementia

Adam M. Staffaroni, Sheng-Yang Matthew Goh, Yann Cobigo, Elise Ong, Suzee E. Lee, Kaitlin B. Casaletto, Amy Wolf, Leah K. Forsberg, Nupur Ghoshal, Neill R. Graff-Radford, Murray Grossman, Hilary W. Heuer, Ging-Yuek Robin Hsiung, Kejal Kantarci, David S. Knopman, Walter K. Kremers, Ian R. Mackenzie, Bruce L. Miller, Otto Pedraza, Katya Rascovsky, Carmela Tartaglia, Zbigniew Wszolek, Joel H. Kramer, John Kornak, Bradley F. Boeve, Adam L. Boxer, Howard J. Rosen

Tracking neurodegeneration in frontotemporal dementia and Alzheimer’s disease: A comparative study of plasma tau and neurofilament light chain.

Alzheimer's & Dementia

Ignacio Illán-Gala, Alberto Lleó, Anna M. Karydas, Adam M. Staffaroni, Henrik Zetterberg, Rajeev Sivasankaran, Lea Tenenholz Grinberg, Salvatore Spina, Joel H. Kramer, Eliana Marisa Ramos, Giovanni Coppolla, Renaud Joie, Gil D. Rabinovici, David C. Perry, Maria Luisa Gorno Tempini, William W. Seeley, Howard J. Rosen, Adam L. Boxer, Julio C. Rojas

Brain volumetric deficits in MAPT mutation carriers: a multisite study.

Annals of clinical and translational neurology

Chu SA, Flagan TM, Staffaroni AM, Jiskoot LC, Deng J, Spina S, Zhang L, Sturm VE, Yokoyama JS, Seeley WW, Papma JM, Geschwind DH, Rosen HJ, Boeve BF, Boxer AL, Heuer HW, Forsberg LK, Brushaber DE, Grossman M, Coppola G, Dickerson BC, Bordelon YM, Faber K, Feldman HH, Fields JA, Fong JC, Foroud T, Gavrilova RH, Ghoshal N, Graff-Radford NR, Hsiung GR, Huey ED, Irwin DJ, Kantarci K, Kaufer DI, Karydas AM, Knopman DS, Kornak J, Kramer JH, Kukull WA, Lapid MI, Litvan I, Mackenzie IRA, Mendez MF, Miller BL, Onyike CU, Pantelyat AY, Rademakers R, Marisa Ramos E, Roberson ED, Carmela Tartaglia M, Tatton NA, Toga AW, Vetor A, Weintraub S, Wong B, Wszolek ZK

Development and validation of the Uniform Data Set (v3.0) executive function composite score (UDS3-EF).

Alzheimer's & dementia : the journal of the Alzheimer's Association

Staffaroni AM, Asken BM, Casaletto KB, Fonseca C, You M, Rosen HJ, Boxer AL, Elahi FM, Kornak J, Mungas D, Kramer JH

Plasma tau and neurofilament light in frontotemporal lobar degeneration and Alzheimer's disease.

Neurology

Illán-Gala I, Lleo A, Karydas A, Staffaroni AM, Zetterberg H, Sivasankaran R, Grinberg LT, Spina S, Kramer J, Ramos EM, Coppola G, La Joie R, Rabinovici GD, Perry DC, Gorno-Tempini ML, Seeley W, Miller BL, Rosen HJ, Blennow K, Boxer AL, Rojas JC

Digital Cognitive Assessments for Dementia: Digital assessments may enhance the efficiency of evaluations in neurology and other clinics.

Practical neurology (Fort Washington, Pa.)

Staffaroni AM, Tsoy E, Taylor J, Boxer AL, Possin KL

Worth the Wait: Delayed Recall after 1 Week Predicts Cognitive and Medial Temporal Lobe Trajectories in Older Adults.

Journal of the International Neuropsychological Society : JINS

Lindbergh CA, Walker N, La Joie R, Weiner-Light S, Staffaroni AM, Casaletto KB, Elahi F, Walters SM, You M, Cotter D, Asken B, Apple AC, Tsoy E, Neuhaus J, Fonseca C, Wolf A, Cobigo Y, Rosen H, Kramer JH

Sex-related differences in the relationship between ß-amyloid and cognitive trajectories in older adults.

Neuropsychology

Lindbergh CA, Casaletto KB, Staffaroni AM, La Joie R, Iaccarino L, Edwards L, Tsoy E, Elahi F, Walters SM, Cotter D, You M, Apple AC, Asken B, Neuhaus J, Rexach JE, Wojta KJ, Rabinovici G, Kramer JH

Rates of Brain Atrophy Across Disease Stages in Familial Frontotemporal Dementia Associated With MAPT, GRN, and C9orf72 Pathogenic Variants.

JAMA network open

Staffaroni AM, Goh SM, Cobigo Y, Ong E, Lee SE, Casaletto KB, Wolf A, Forsberg LK, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Hsiung GR, Kantarci K, Knopman DS, Kremers WK, Mackenzie IR, Miller BL, Pedraza O, Rascovsky K, Tartaglia MC, Wszolek ZK, Kramer JH, Kornak J, Boeve BF, Boxer AL, Rosen HJ

Salience Network Atrophy Links Neuron Type-Specific Pathobiology to Loss of Empathy in Frontotemporal Dementia.

Cerebral cortex (New York, N.Y. : 1991)

Pasquini L, Nana AL, Toller G, Brown JA, Deng J, Staffaroni A, Kim EJ, Hwang JL, Li L, Park Y, Gaus SE, Allen I, Sturm VE, Spina S, Grinberg LT, Rankin KP, Kramer JH, Rosen HJ, Miller BL, Seeley WW

Baseline neuropsychological profiles in prion disease predict survival time.

Annals of clinical and translational neurology

Sundaram SE, Staffaroni AM, Walker NC, Casaletto KB, Casey M, Golubjatnikov A, Metcalf S, O'Leary K, Wong K, Benisano K, Forner S, Gonzalez Catalan M, Allen IE, Rosen HJ, Kramer JH, Geschwind MD

Systemic Tumor Necrosis Factor-Alpha Trajectories Relate to Brain Health in Typically Aging Older Adults.

The journals of gerontology. Series A, Biological sciences and medical sciences

Lindbergh CA, Casaletto KB, Staffaroni AM, Elahi F, Walters SM, You M, Neuhaus J, Rivera Contreras W, Wang P, Karydas A, Brown J, Wolf A, Rosen H, Cobigo Y, Kramer JH

REM sleep is associated with white matter integrity in cognitively healthy, older adults.

PloS one

Altendahl M, Cotter DL, Staffaroni AM, Wolf A, Mumford P, Cobigo Y, Casaletto K, Elahi F, Ruoff L, Javed S, Bettcher BM, Fox E, You M, Saloner R, Neylan TC, Kramer JH, Walsh CM

Longitudinal structural and metabolic changes in frontotemporal dementia.

Neurology

Bejanin A, Tammewar G, Marx G, Cobigo Y, Iaccarino L, Kornak J, Staffaroni AM, Dickerson BC, Boeve BF, Knopman DS, Gorno-Tempini M, Miller BL, Jagust WJ, Boxer AL, Rosen HJ, Rabinovici GD

Caregiver "objective attitude" toward patients with neurodegenerative disease: Consequences for caregiver strain and relationship closeness.

Aging & mental health

Zahir A, Staffaroni AM, Wickham RE, Quinn CM, Sapozhnikova A, Seidman J, Chiong W

Aging and Positive Mood: Longitudinal Neurobiological and Cognitive Correlates.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Cotter DL, Walters SM, Fonseca C, Wolf A, Cobigo Y, Fox EC, You MY, Altendahl M, Djukic N, Staffaroni AM, Elahi FM, Kramer JH, Casaletto KB

Sexual dimorphism of physical activity on cognitive aging: Role of immune functioning.

Brain, behavior, and immunity

Casaletto KB, Lindbergh C, Memel M, Staffaroni A, Elahi F, Weiner-Light S, You M, Fonseca C, Karydas A, Jacobs E, Dubal DB, Yaffe K, Kramer JH

Revised Self-Monitoring Scale: A potential endpoint for frontotemporal dementia clinical trials.

Neurology

Toller G, Ranasinghe K, Cobigo Y, Staffaroni A, Appleby B, Brushaber D, Coppola G, Dickerson B, Domoto-Reilly K, Fields J, Fong J, Forsberg L, Ghoshal N, Graff-Radford N, Grossman M, Heuer H, Hsiung GY, Huey E, Irwin D, Kantarci K, Kaufer D, Kerwin D, Knopman D, Kornak J, Kramer J, Litvan I, Mackenzie I, Mendez M, Miller B, Rademakers R, Ramos E, Rascovsky K, Roberson E, Syrjanen J, Tartaglia C, Weintraub S, Boeve B, Boxer A, Rosen H, Rankin K

Get Moving! Increases in Physical Activity Are Associated With Increasing Functional Connectivity Trajectories in Typically Aging Adults.

Frontiers in aging neuroscience

Dorsman KA, Weiner-Light S, Staffaroni AM, Brown JA, Wolf A, Cobigo Y, Walters S, Kramer JH, Casaletto KB

Association of Cognitive and Behavioral Features Between Adults With Tuberous Sclerosis and Frontotemporal Dementia.

JAMA neurology

Liu AJ, Staffaroni AM, Rojas-Martinez JC, Olney NT, Alquezar-Burillo C, Ljubenkov PA, La Joie R, Fong JC, Taylor J, Karydas A, Ramos EM, Coppola G, Boxer AL, Rabinovici GD, Miller BL, Kao AW

Differential cognitive substrates of verbal episodic memory performance in semantic variant primary progressive aphasia and Alzheimer's disease.

Journal of neuropsychology

DeVaughn S, Casaletto KB, Staffaroni AM, Wolf AA, Marx G, Kramer JH

Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Olney NT, Ong E, Goh SM, Bajorek L, Dever R, Staffaroni AM, Cobigo Y, Bock M, Chiang K, Ljubenkov P, Kornak J, Heuer HW, Wang P, Rascovsky K, Wolf A, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dickerson BC, Dickinson S, Domoto-Reilly K, Faber K, Ferrall J, Fields J, Fishman A, Fong J, Foroud T, Forsberg LK, Gearhart DJ, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford NR, Grant I, Grossman M, Haley D, Hsiung G, Huey ED, Irwin DJ, Jones DT, Kantarci K, Karydas AM, Kaufer D, Kerwin D, Knopman DS, Kramer JH, Kraft R, Kremers W, Kukull W, Lapid MI, Litvan I, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley EC, Mendez MF, Miller BL, Onyike C, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wong B, Wszolek Z, Boxer AL, Boeve BF, Rosen HJ

Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Staffaroni AM, Cobigo Y, Goh SM, Kornak J, Bajorek L, Chiang K, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dever R, Dheel C, Dickerson BC, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fields JA, Fishman A, Fong J, Foroud T, Forsberg LK, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Heuer HW, Hsiung GY, Huey ED, Irwin DJ, Jones DT, Jones L, Kantarci K, Karydas A, Kaufer DI, Kerwin DR, Knopman DS, Kraft R, Kramer JH, Kremers WK, Kukull WA, Litvan I, Ljubenkov PA, Lucente D, Lungu C, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley E, Mendez MF, Miller BL, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wang P, Wong B, Wszolek Z, Boxer AL, Boeve BF, Rosen HJ

Active lifestyles moderate clinical outcomes in autosomal dominant frontotemporal degeneration.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Casaletto KB, Staffaroni AM, Wolf A, Appleby B, Brushaber D, Coppola G, Dickerson B, Domoto-Reilly K, Elahi FM, Fields J, Fong JC, Forsberg L, Ghoshal N, Graff-Radford N, Grossman M, Heuer HW, Hsiung GY, Huey ED, Irwin D, Kantarci K, Kaufer D, Kerwin D, Knopman D, Kornak J, Kramer JH, Litvan I, Mackenzie IR, Mendez M, Miller B, Rademakers R, Ramos EM, Rascovsky K, Roberson ED, Syrjanen JA, Tartaglia MC, Weintraub S, Boeve B, Boxer AL, Rosen H, Yaffe K

Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Staffaroni AM, Bajorek L, Casaletto KB, Cobigo Y, Goh SM, Wolf A, Heuer HW, Elahi FM, Ljubenkov PA, Dever R, Kornak J, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dheel C, Dickerson BC, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fields JA, Fishman A, Fong J, Foroud T, Forsberg LK, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Hsiung GY, Huey ED, Irwin DJ, Jones DT, Jones L, Kantarci K, Karydas A, Kaufer DI, Kerwin DR, Knopman DS, Kraft R, Kremers WK, Kukull WA, Litvan I, Lucente D, Lungu C, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley E, Mendez MF, Miller BL, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wang P, Wong B, Wszolek Z, Boxer AL, Boeve BF, Kramer JH, Rosen HJ

Plasma Glial Fibrillary Acidic Protein Levels Differ Along the Spectra of Amyloid Burden and Clinical Disease Stage.

Journal of Alzheimer's disease : JAD

Asken BM, Elahi FM, La Joie R, Strom A, Staffaroni AM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Karydas A, Wang P, Rojas JC, Boxer AL, Miller BL, Rabinovici GD, Kramer JH, Casaletto KB

Nonlinear Z-score modeling for improved detection of cognitive abnormality.

Alzheimer's & dementia (Amsterdam, Netherlands)

Kornak J, Fields J, Kremers W, Farmer S, Heuer HW, Forsberg L, Brushaber D, Rindels A, Dodge H, Weintraub S, Besser L, Appleby B, Bordelon Y, Bove J, Brannelly P, Caso C, Coppola G, Dever R, Dheel C, Dickerson B, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fishman A, Fong J, Foroud T, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant IM, Grossman M, Haley D, Hsiao J, Hsiung R, Huey ED, Irwin D, Jones D, Jones L, Kantarci K, Karydas A, Kaufer D, Kerwin D, Knopman D, Kraft R, Kramer J, Kukull W, Lapid M, Litvan I, Ljubenkov P, Lucente D, Lungu C, Mackenzie I, Maldonado M, Manoochehri M, McGinnis S, McKinley E, Mendez M, Miller B, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin K, Rascovsky K, Roberson ED, Rogalski-Miller E, Sengdy P, Shaw L, Staffaroni AM, Sutherland M, Syrjanen J, Tartaglia C, Tatton N, Taylor J, Toga A, Trojanowski J, Wang P, Wong B, Wszolek Z, Boeve B, Boxer A, Rosen H

State and trait characteristics of anterior insula time-varying functional connectivity.

NeuroImage

Pasquini L, Toller G, Staffaroni A, Brown JA, Deng J, Lee A, Kurcyus K, Shdo SM, Allen I, Sturm VE, Cobigo Y, Borghesani V, Battistella G, Gorno-Tempini ML, Rankin KP, Kramer J, Rosen HH, Miller BL, Seeley WW

Peripheral Innate Immune Activation Correlates With Disease Severity in GRN Haploinsufficiency.

Frontiers in neurology

Ljubenkov PA, Miller Z, Mumford P, Zhang J, Allen IE, Mitic L, Staffaroni A, Heuer H, Rojas JC, Cobigo Y, Karydas A, Pearlman R, Miller B, Kramer JH, McGrath MS, Rosen HJ, Boxer AL

C-24 Longitudinal Trajectories of Working Memory Performance in Typically Aging Older Adults.

Archives of Clinical Neuropsychology

M Gonzalez Catalan, C Lindbergh, A Staffaroni, S Walters, K Casaletto, N Walker, J Kramer

Association of Blood and Cerebrospinal Fluid Tau Level and Other Biomarkers With Survival Time in Sporadic Creutzfeldt-Jakob Disease.

JAMA neurology

Staffaroni AM, Kramer AO, Casey M, Kang H, Rojas JC, Orrú CD, Caughey B, Allen IE, Kramer JH, Rosen HJ, Blennow K, Zetterberg H, Geschwind MD

Robust normative standards for the California Verbal Learning Test (CVLT) ages 60-89: A tool for early detection of memory impairment.

The Clinical neuropsychologist

Kramer AO, Casaletto KB, Umlauf A, Staffaroni AM, Fox E, You M, Kramer JH

STEP COUNT AND PSYCHOLOGICAL HEALTH IN OLDER ADULTS.

Alzheimer's & Dementia

Sophia A. Weiner-Light, Samantha Walters, Nina Djukic, Michelle You, Devyn Cotter, Marie Altendahl, Fanny Elahi, Adam M. Staffaroni, Cutter A. Lindbergh, Joel H. Kramer, Kaitlin B. Casaletto

THE MULTIDOMAIN IMPAIRMENT RATING (MIR) SCALE: INITIAL RELIABILITY DATA ON A MULTIDIMENSIONAL SCALE DESIGNED FOR FTLD SPECTRUM DISORDERS.

Alzheimer's & Dementia

Leah K. Forsberg, Bradley F. Boeve, Adam L. Boxer, Howard J. Rosen, John Kornak, Hilary W. Heuer, Julie A. Fields, Danielle Brushaber, Mary M. Machulda, Virginia Sturm, Adam M. Staffaroni, Peter A. Ljubenkov, Reilly Denver, Elise Ong, Brian Appleby, Yvette M. Bordelon, Patrick Brannelly, Giovanni Coppola, Brad C. Dickerson, Susan Dickinson, Domoto-Reilly Kimiko, Kelley Faber, Jamie Fong, Tatiana M. Foroud, Ralitza H. Gavrilova, Debra Gearhart, Nupur Ghoshal, Jill Goldman, Jonathan Graff-Radford, Neil R. Graff-Radford, Murray Grossman, Ging-Yuek Robin Hsiung, Edward D. Huey, David Irwin, David T. Jones, Kejal Kantarci, Anna M. Karydas, Daniel Kaufer, Diana R. Kerwin, David S. Knopman, Ruth A. Kraft, Joel H. Kramer, Walter K. Kremers, Walter A. Kukull, Irene Litvan, Diane E. Lucente, Codrin Lungu, Ian R. Mackenzie, Scott M. McGinnis, Mario F. Mendez, Bruce L. Miller, Chiadi U. Onyike, Alex Pantelyat, Rodney Pearlman, Leonard Petrucelli, Madeline Potter, Rosa Rademakers, Eliana Marisa Ramos, Katherine Rankin, Katya Rascovsky, Erik D. Roberson, Emily J. Rogalski, Leslie M. Shaw, Marg Sutherland, Jeremy Syrjanen, Carmela Tartaglia, Nadine Tatton, Joanne Taylor, Arthur W. Toga, John Q. Trojanowski, Sandra Weintraub, Bonnie Wong, Zbigniew Wszolek

Frontotemporal Dementia.

Andrea G. Alioto, Christie C. Mead, Alicia B. Vanden Bussche Jantz, Adam M. Staffaroni, Joel H. Kramer

A longitudinal characterization of perfusion in the aging brain and associations with cognition and neural structure.

Human brain mapping

Staffaroni AM, Cobigo Y, Elahi FM, Casaletto KB, Walters SM, Wolf A, Lindbergh CA, Rosen HJ, Kramer JH

Efficacy of Mindfulness-Based Cognitive Training in Surgery: Additional Analysis of the Mindful Surgeon Pilot Randomized Clinical Trial.

JAMA network open

Lebares CC, Guvva EV, Olaru M, Sugrue LP, Staffaroni AM, Delucchi KL, Kramer JH, Ascher NL, Harris HW

Plasma neurofilament light chain predicts disease progression in asymptomatic genetic frontotemporal dementia (P5.1-007).

Neurology

Julio Rojas -Martinez, Ping Wang, Adam Staffaroni, Yann Cobigo, Amy Wolf, Hilary Heuer, Jamie Fong, Joanne Taylor, Andreas Jeromin, Howard Rosen, Bradley Boeve, Adam Boxer

Longitudinal multimodal imaging and clinical endpoints for frontotemporal dementia clinical trials.

Brain : a journal of neurology

Staffaroni AM, Ljubenkov PA, Kornak J, Cobigo Y, Datta S, Marx G, Walters SM, Chiang K, Olney N, Elahi FM, Knopman DS, Dickerson BC, Boeve BF, Gorno-Tempini ML, Spina S, Grinberg LT, Seeley WW, Miller BL, Kramer JH, Boxer AL, Rosen HJ

Cognitive aging is not created equally: differentiating unique cognitive phenotypes in "normal" adults.

Neurobiology of aging

Casaletto KB, Elahi FM, Staffaroni AM, Walters S, Contreras WR, Wolf A, Dubal D, Miller B, Yaffe K, Kramer JH

Primary School Education May Be Sufficient to Moderate a Memory-Hippocampal Relationship.

Frontiers in aging neuroscience

Resende EPF, Rosen HJ, Chiang K, Staffaroni AM, Allen I, Grinberg LT, Carmona KC, Guimarães HC, Carvalho VA, Barbosa MT, de Souza LC, Caramelli P

"Liquid Biopsy" of White Matter Hyperintensity in Functionally Normal Elders.

Frontiers in aging neuroscience

Elahi FM, Casaletto KB, Altendahl M, Staffaroni AM, Fletcher E, Filshtein TJ, Glymour MM, Miller BL, Hinman JD, DeCarli C, Goetzl EJ, Kramer JH

Cerebrospinal fluid biomarkers predict frontotemporal dementia trajectory.

Annals of clinical and translational neurology

Ljubenkov PA, Staffaroni AM, Rojas JC, Allen IE, Wang P, Heuer H, Karydas A, Kornak J, Cobigo Y, Seeley WW, Grinberg LT, Spina S, Fagan AM, Jerome G, Knopman D, Boeve BF, Dickerson BC, Kramer J, Miller B, Boxer AL, Rosen HJ

ENDOTHELIAL-DERIVED EXOSOME BIOMARKERS SUGGEST ACTIVATION OF INNATE IMMUNITY IN SUBCLINICAL CEREBROVASCULAR DISEASE.

Alzheimer's & Dementia

Fanny Elahi, Marie Altendahl, Teresa J. Filshtein, Kaitlin Casaletto, Adam M. Staffaroni, Wilfredo Rivera Contreras, Anna M. Karydas, Yann Cobigo, Evan Fletcher, Baljeet Singh, Oliver Martinez, Howard J. Rosen, Jason Hinman, Katerina Akassoglou, Maria Glymour, Charlie S. DeCarli, Edward J. Goetzl, Joel H. Kramer

PRIMARY SCHOOL EDUCATION CAN BE SUFFICIENT TO MODERATE THE RELATIONSHIP BETWEEN HIPPOCAMPUS VOLUME AND MEMORY PERFORMANCE.

Alzheimer's & Dementia

Elisa de Paula França Resende, Howard J. Rosen, Kevin Chiang, Isabel Allen, Adam M. Staffaroni, Lea Tenenholz Grinberg, Karoline Carvalho Carmona, Henrique Cerqueira Guimaraes, Viviane Amaral Carvalho, Maira Tonidandel Barbosa, Leonardo Cruz de Souza, Paulo Caramelli

THE NIH-EXAMINER IS SENSITIVE TO COGNITIVE CHANGES IN ASYMPTOMATIC AND MILDLY SYMPTOMATIC FAMILIAL FRONTOTEMPORAL DEMENTIA.

Alzheimer's & Dementia

Adam M. Staffaroni, Lynn Bajorek, Peter Ljubenkov, Kaitlin Casaletto, Fanny Elahi, Katya Rascovsky, Bradley F. Boeve, Adam L. Boxer, Jessica Bove, Danielle Brushaber, Giovanni Coppola, Christina Dheel, Brad C. Dickerson, Julie A. Fields, Jamie Fong, Leah K. Forsberg, Ralitza H. Gavrilova, Debra Gearhart, Nupur Ghoshal, Jill Goldman, Jonathan Graff Radford, Neill R. Graff-Radford, Murray Grossman, Dana Haley, Hilary W. Heuer, John Hsiao, Ging-Yuek Robin Hsiung, Edward Huey, David J. Irwin, David T. Jones, Lynne Jones, Kejal Kantarci, Anna M. Karydas, David S. Knopman, John Kornak, Walter K. Kremers, Walter A. Kukull, Maria I. Lapid, Diane Lucente, Ian R. Mackenzie, Masood Manoochehri, Bruce L. Miller, Madeline Potter, Rosa Rademakers, Katherine Rankin, Margaret Sutherland, Jeremy Syrjanen, Joanne Taylor, Sandra Weintraub, Bonnie Wong, Zbigniew Wszolek, Howard J. Rosen, Joel H. Kramer, ARTFL/LEFFTDS Consortium

Perceived Stress is Associated with Accelerated Monocyte/Macrophage Aging Trajectories in Clinically Normal Adults.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Casaletto KB, Staffaroni AM, Elahi F, Fox E, Crittenden PA, You M, Neuhaus J, Glymour M, Bettcher BM, Yaffe K, Kramer JH

A comparison of biofluid cytokine markers across platform technologies: Correspondence or divergence?

Cytokine

Casaletto KB, Elahi FE, Fitch R, Walters S, Fox E, Staffaroni AM, Bettcher B, Zetterberg H, Karydas A, Rojas JC, Boxer AL, Kramer JH

Telomere attrition is associated with declines in medial temporal lobe volume and white matter microstructure in functionally independent older adults.

Neurobiology of aging

Staffaroni AM, Tosun D, Lin J, Elahi FM, Casaletto KB, Wynn MJ, Patel N, Neuhaus J, Walters SM, Epel ES, Blackburn EH, Kramer JH

Biomarkers of Cerebral Small Vessel Endotheliopathy (S48.005).

Neurology

Fanny Elahi, Marie Altendahl, Adam Staffaroni, Kaitlin Casaletto, Pauline Maillard, John Neuhaus, Jason Hinman, Charles DeCarli, Edward Goetzl, Joel Kramer

Clinical Dementia Rating Score 0.5 Predicts Clinical Decline in Familial Frontotemporal Dementia (S48.007).

Neurology

Salvatore Spina, Adam Staffaroni, Luke Bonham, Nicholas Olney, Suneth Attygalle, Yann Cobigo, Kevin Chang, Richard Binney, Jennifer Yokoyama, John Kornak, Adam Boxer, Bruce Miller, Suzee Lee, Bradley Boeve, Howie Rosen

Multimodal MRI Staging Improves Clinico-Imaging Correlations in sJCD. (P3.177).

Neurology

Simone Sacco, Eduardo Caverzasi, Matteo Paoletti, Adam Staffaroni, Isabel Allen, Gabriel Marx, Joel Kramer, Stefano Bastianello, Roland Henry, Howard Rosen, Michael Geschwind

Peripheral Innate Immune Activation Correlates with Disease Severity in GRN Mutation Carriers (P4.178).

Neurology

Peter Ljubenkov, Paige Mumford, Michael McGrath, Isabel Elaine Allen, Zachary Miller, Laura Mitic, Anna Karydas, Hilary Heuer, Julio Rojas-Martinez, Ping Wang, Jane Zhang, Adam Staffaroni, Yann Cobigo, Rodney Pearlman, Bruce Miller, Howie Rosen, Adam Boxer

Plasma Biomarkers in Early Neurodegenerative Disease Stages (P3.027).

Neurology

Fanny Elahi, Kaitlin Casaletto, Adam Staffaroni, John Neuhaus, Yann Cobigo, Emily Fox, Samantha Walters, Marie Altendahl, Ryan Fitch, Anna Karydas, Jason Hinman, Charles DeCarli, Adam Boxer, Gil Rabinovici, Howard Rosen, Bruce Miller, Joel Kramer

The Longitudinal Trajectory of Default Mode Network Connectivity in Healthy Older Adults Varies As a Function of Age and Is Associated with Changes in Episodic Memory and Processing Speed.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Staffaroni AM, Brown JA, Casaletto KB, Elahi FM, Deng J, Neuhaus J, Cobigo Y, Mumford PS, Walters S, Saloner R, Karydas A, Coppola G, Rosen HJ, Miller BL, Seeley WW, Kramer JH

Neuroimaging in Dementia.

Seminars in neurology

Staffaroni AM, Elahi FM, McDermott D, Marton K, Karageorgiou E, Sacco S, Paoletti M, Caverzasi E, Hess CP, Rosen HJ, Geschwind MD

Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease.

NeuroImage. Clinical

Elahi FM, Marx G, Cobigo Y, Staffaroni AM, Kornak J, Tosun D, Boxer AL, Kramer JH, Miller BL, Rosen HJ

Data-driven regions of interest for longitudinal change in three variants of frontotemporal lobar degeneration.

Brain and behavior

Binney RJ, Pankov A, Marx G, He X, McKenna F, Staffaroni AM, Kornak J, Attygalle S, Boxer AL, Schuff N, Gorno-Tempini ML, Weiner MW, Kramer JH, Miller BL, Rosen HJ

The functional neuroanatomy of verbal memory in Alzheimer's disease: [18F]-Fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) correlates of recency and recognition memory.

Journal of clinical and experimental neuropsychology

Staffaroni AM, Melrose RJ, Leskin LP, Riskin-Jones H, Harwood D, Mandelkern M, Sultzer DL

Progression of Brain Atrophy and Cognitive Impairment in Hereditary Frontotemporal Lobar Degeneration (P6.247).

Neurology

Salvatore Spina, Howie Rosen, Adam Staffaroni, Luke Bonham, Suneth Attygalle, John Kornak, Joel Kramer, Bruce Miller, Suzee Lee

Data-driven regions of interest for longitudinal change in frontotemporal lobar degeneration.

NeuroImage. Clinical

Pankov A, Binney RJ, Staffaroni AM, Kornak J, Attygalle S, Schuff N, Weiner MW, Kramer JH, Dickerson BC, Miller BL, Rosen HJ

CapMan: independent investigation of capacity and manipulation with a new working memory paradigm.

Brain imaging and behavior

Dobryakova E, Staffaroni A, DeLuca J, Sumowski JF, Chiaravalloti N, Wylie GR